Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T52522 | Target Info | |||
| Target Name | Adrenergic receptor beta-2 (ADRB2) | ||||
| Synonyms |
Beta-2 adrenoreceptor; Beta-2 adrenoceptor; Beta-2 adrenergic receptor; B2AR; ADRB2R
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| Target Type | Successful Target | ||||
| Gene Name | ADRB2 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 134 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Dopamine
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|
Approved | Compound Info | ||
| Synonyms |
Dopamin; Dopamina; Dopaminum; Dophamine; Hydroxytyramin; Hydroxytyramine; Intropin; LDP; Oxytyramine; Revimine; ASL 279; IP 498; Dopamina [INN-Spanish]; Dopamine (INN); Dopamine [INN:BAN]; Dopaminum [INN-Latin]; L-DOPAMINE; M-Hydroxytyramine hydrochloride; Medopa (TN); Intropin [*hydrochloride*]; KW-3-060; Beta-(3,4-Dihydroxyphenyl)ethylamine hydrochloride; Dopamine (USAN)(*hydrochloride*); A-(3,4-Dihydroxyphenyl)-b-aminoethane; Alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane; Pyrocatechol, 4-(2-aminoethyl)-(8CI); Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride; (3H)-Dopamine; 1,2-Benzenediol, 4-(2-aminoethyl)-(9CI); 1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride; 1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium; 153C5321-5FEE-4B0B-8925-F388F0EEEBD1; 2-(3,4-dihydroxyphenyl)ethylamine; 2-benzenediol; 3,4-Dihydroxyphenethylamine hydrochloride; 3,4-Dihydroxyphenylethylamine; 3,4-dihydroxyphenethylamine; 3-Hydroxtyramine; 3-Hydroxytyramine; 3-Hydroxytyramine Hydrobromide; 3-Hydroxytyramine hydrochloride; 4-(2-Aminoethyl)-1; 4-(2-Aminoethyl)-1,2-benzenediol; 4-(2-Aminoethyl)-1,2-bezenediol; 4-(2-Aminoethyl)benzene-1,2-diol; 4-(2-Aminoethyl)catechol; 4-(2-Aminoethyl)pyrocatechol; 4-(2-Aminoethyl)pyrocatechol hydrochloride; 4-(2-aminoethyl)-pyrocatechol
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| Activity |
Ki = 61000 nM
|
[1] | |||
| Compound Name |
Norepinephrine
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Approved | Compound Info | ||
| Synonyms |
norepinephrine; L-Noradrenaline; Levarterenol; 51-41-2; L-Norepinephrine; Levophed; (-)-Norepinephrine; L-arterenol; (R)-Noradrenaline; (R)-Norepinephrine; Levonor; Levonorepinephrine; Adrenor; Aktamin; Levonoradrenaline; Sympathin E; (R)-(-)-Norepinephrine; 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol; Noradrenalin; Norepirenamine; norepinephrinum; Noradrenalinum; Levoarterenol; Norartrinal; Nor-Epirenan; L-3,4-dihydroxyphenylethanolamine; Levarterenolo; Noreinefrina; Norepinefrina; Norepinephrinum; Levarterenolo [DCIT]; Nor adrenalin; Noradrenalina [Italian]; Norepinephrine Noradrenalin; LT03330026; ALBB-006229; Nor adrenalin (TN); Noradrenaline (JP15); Noreinefrina [INN-Spanish]; Norepinephrine (INN); Norepinephrine [INN:JAN]; Norepinephrinum [INN-Latin]; Norepinephrine l-Tartrate (1:1); D-(-)-Noradrenaline; D53D5E3A-2360-4CA9-8031-6C2CD4062FD5; L-alpha-(aminomethyl)-3,4-dihydroxybenzyl alcohol; L-1-(3,4-Dihydroxyphenyl)-2-aminoethanol; L-2-Amino-1-(3,4-dihydroxyphenyl)ethanol; (-)-(R)-Norepinephrine; (-)-Arterenol free base; (-)-alpha-(Aminomethyl)protocatechuyl alcohol; (R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol; 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)-(9CI); 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol; Ecteinascidins
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| Activity |
Ki = 96700 nM
|
[2] | |||
| Compound Name |
Pramipexole
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Approved | Compound Info | ||
| Synonyms |
Mirapex; Pramipexol; Pramipexolum; SUD919CL2Y; Mirapex (TN); Mirapexin (TN); Pramipexole [USAN:INN]; SND-919; Sifrol(TN); U-98528E; Pramipexole (USAN/INN); (-)-Pramipexole; (6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine; (6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine; (6S)-N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine; (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole; 111GE001; 2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole; 2-amino-6-propylaminotetrahydrobenzothiazole
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| Activity |
Ki = 100000 nM
|
[1] | |||
| Compound Name |
6-fluoronorepinehprine
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Investigative | Compound Info | ||
| Synonyms |
6-fluoronorepinehprine; CHEMBL295072; 2-Fluoronorepinephrine; fluoronorepinephrine; BDBM50087518
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| Activity |
Ki = 70100 nM
|
[2] | |||
| Compound Name |
QUINPIROLE
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Investigative | Compound Info | ||
| Synonyms |
Quinpirolum; Quinpirol; Quinpirole [INN]; Quinpirolum [Latin]; Quinpirol [Spanish]; 80373-22-4; UNII-20OP60125T; CHEBI:75401; LY 156258; CHEMBL240773; (4aR-trans)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo(3,4-g)quinoline; 20OP60125T; 1H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR-trans)-; (4aR,8aR)-5-propyl-1,4,4a,6,7,8,8a,9-octahydropyrido[2,3-f]indazole; (4aR,8aR)-5-propyl-1,4,4a,6,7,8,8a,9-octahydropyrazolo[3,4-g]quinoline
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| Activity |
Ki = 100000 nM
|
[1] | |||
| Compound Name |
4-[4-[[(Betar)-beta,4-Dihydroxy-3-(methylsulfonylamino)phenethyl]amino]piperidino]benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL284311; SCHEMBL6074538; BDBM50098657
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| Activity |
EC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[3-(4-methoxy-butyl)-2-oxo-imidazolidin-1-yl]-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL434284; BDBM50075900
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| Activity |
IC50 = 50000 nM
|
[4] | |||
| Compound Name |
N-[4-[2-[[(2R)-2-Hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]propane-2-sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL104377; BDBM50072386; Propane-2-sulfonic acid {4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-amide
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| Activity |
IC50 = 50000 nM
|
[5] | |||
| Compound Name |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[4-(1H-indol-3-yl)-thiazol-2-yl]-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL291516; BDBM50091771
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| Activity |
IC50 = 50000 nM
|
[6] | |||
| Compound Name |
4-[1-Hydroxy-2-[[4-[[[2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]methyl]phenyl]methylamino]ethyl]-2-(hydroxymethyl)phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1940809; SCHEMBL4869352; BDBM50419655
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| Activity |
IC50 = 50118.72 nM
|
[7] | |||
| Compound Name |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[5-(3-oxo-3-pyrrolidin-1-yl-propyl)-[1,2,4]oxadiazol-3-yl]-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL32996; BDBM50089456
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| Activity |
IC50 = 51000 nM
|
[8] | |||
| Compound Name |
Chembl4204907
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Investigative | Compound Info | ||
| Synonyms |
BDBM50454563
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| Activity |
Ki = 52300 nM
|
[9] | |||
| Compound Name |
(S,S)-(+)-5-[1-Hydroxy-2-(1-methylhexylamino)ethyl]-1,3-benzenediol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL389734; BDBM50213105
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|
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| Activity |
Ki = 56234.13 nM
|
[10] | |||
| Compound Name |
5-[(1S)-2-[[(2S)-Heptan-2-yl]amino]-1-hydroxyethyl]benzene-1,3-diol
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL2488461; CHEMBL3918348; BDBM206778; (S,S)-6; US9492405, (S,S)-6
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| Activity |
Ki = 56420 nM
|
[11] | |||
| Compound Name |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[5-(4-oxo-pentyl)-[1,2,4]oxadiazol-3-yl]-benzenesulfonamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL286800; BDBM50089464
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| Activity |
IC50 = 57000 nM
|
[8] | |||
| Compound Name |
(4-{(R)-2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-phenoxymethyl)-methyl-phosphinic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL39334; BDBM50289565
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| Activity |
Ki = 73700 nM
|
[12] | |||
| Compound Name |
2-[4-[4-[[(R)-beta,4-Dihydroxy-3-(methylsulfonylamino)phenethyl]amino]piperidino]benzyl]tetrahydro-1,2,4-oxadiazole-3,5-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL368584; SCHEMBL6074720; BDBM50099150
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| Activity |
Ki = 74000 nM
|
[13] | |||
| Compound Name |
Chembl4218602
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Investigative | Compound Info | ||
| Synonyms |
BDBM50454560
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| Activity |
Ki = 74000 nM
|
[9] | |||
| Compound Name |
(4-(Pyrimidin-2-yl)phenyl)methanamine
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Investigative | Compound Info | ||
| Synonyms |
4-Pyrimidin-2-ylbenzylamine; (4-pyrimidin-2-ylphenyl)methanamine; CHEMBL4210507; [4-(pyrimidin-2-yl)phenyl]methanamine; SCHEMBL2427481; CTK5G0726; DTXSID90640272; (4-pyrimidin-2-ylphenyl)methylamine; 4282AC; BDBM50454565; MFCD09817489; SBB090294; ZINC12370550; AKOS006345738; AM86139; Benzenemethanamine,4-(2-pyrimidinyl)-; DS-5437; 1-[4-(Pyrimidin-2-yl)phenyl]methanamine; DB-077881; FT-0741133; L-1988
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| Activity |
Ki = 78100 nM
|
[9] | |||
| Compound Name |
Disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate
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Investigative | Compound Info | ||
| Synonyms |
CL 316,243; CL-316243; UNII-CF9MRO9QWW; CL-316243 sodium; CF9MRO9QWW; CL-316,243; 138908-40-4 (sodium salt); CL316243; BTA-243; CL 316243; CL316,243; CHEMBL32590; CL 316243 disodium; SCHEMBL2016430; DTXSID6041004; HMS3260L12; Tox21_500295; AKOS024456637; LP00295; NCGC00093745-01; NCGC00260980-01; AS-16747; EU-0100295; C 5976; 102718-EP2272841A1; 102718-EP2301936A1; Q27275433
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| Activity |
Ki = 79200 nM
|
[3] | |||
| Compound Name |
Chembl4208846
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Investigative | Compound Info | ||
| Synonyms |
BDBM50454562
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| Activity |
Ki = 80400 nM
|
[9] | |||
| Compound Name |
7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL301559; (7R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol; R(+)-7-Hydroxy-DPAT hydrobromide; NCGC00024742-01; Tocris-0706; Lopac-H-168; Lopac-H-8653; Lopac0_000569; SCHEMBL7568447; (+)-7-OH-DPAT; CTK5E9982; ZINC3870310; BDBM50054067; PDSP1_001712; PDSP2_001695; CCG-204658; SDCCGSBI-0050551.P002; NCGC00015494-01; NCGC00015494-02; NCGC00015494-03; NCGC00162190-02; R(+)-7-HYDROXY-2-DIPROPYLAMINO TETRALIN&; R(+)-7-Hydroxy(dipropylamino)tetralin hydrobromide; r-(+)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin; (2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol; (R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol; (R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol; UNII-RR7D75YDF4 component BLYMJBIZMIGWFK-OAHLLOKOSA-N; (R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol.HCl; 2-Naphthalenol,7-(dipropylamino)-5,6,7,8-tetrahydro-, (7R)-; R(+)-2-Dipropylamino-7-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide; (7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium(R(+)7OH-DPAT)
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| Activity |
Ki = 86000 nM
|
[1] | |||
| Compound Name |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[5-(naphthalen-2-yloxymethyl)-[1,2,4]oxadiazol-3-yl]-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL287562; BDBM50089483
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| Activity |
IC50 = 90000 nM
|
[14] | |||
| Compound Name |
4-[4-(4-Hexyl-phenyl)-thiazol-2-yl]-N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL58241; BDBM50091775
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| Activity |
IC50 = 90000 nM
|
[6] | |||
| Compound Name |
4-(4-Benzo[b]thiophen-2-yl-thiazol-2-yl)-N-{4-[2-((R)-2-hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL291306; BDBM50091774
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| Activity |
IC50 = 93000 nM
|
[6] | |||
| Compound Name |
Chembl4202968
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Investigative | Compound Info | ||
| Synonyms |
BDBM50454553
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| Activity |
Ki = 95400 nM
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[9] | |||
| Compound Name |
(+/-)-N-[5-(2-Bromo-1-hydroxyethyl)isoxazol-3-yl]methanesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL226292; BDBM50205505
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| Activity |
Ki ~ 100000 nM
|
[15] | |||
| Compound Name |
4-[2-[[(2R)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]-N-phenylbenzenesulfonamide;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1204003
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| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-[4-(methanesulfonamido)phenoxy]propyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL511552; BDBM50259164; (S)-4''-(2-{[2-Hydroxy-3-(4-methylsulfonamidophenoxy)-propyl]amino}ethyl)-2-(2-pyridyl)acetanilide
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| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-(3-nitrophenyl)thiourea;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203989
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| Activity |
EC50 ~ 100000 nM
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[16] | |||
| Compound Name |
1-(2-Chlorophenyl)-3-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]thiourea;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2448075
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| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-[(2-oxo-1,3-dihydrobenzimidazol-4-yl)oxy]propyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL466519; BDBM50259167; (S)-4''-(2-{[2-Hydroxy-3-(indol-4-yloxy)propyl]amino}-ethyl)-2-(2-pyridyl)acetanilide
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| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
Chembl4159562
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Investigative | Compound Info | ||
| Synonyms |
BDBM50288240
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| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
3-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dione
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Investigative | Compound Info | ||
| Synonyms |
3-MPPI; CHEMBL301707; NCGC00024664-01; Tocris-0581; Biomol-NT_000127; BPBio1_000310; HMS3266M22; HMS3411G12; HMS3675G12; BDBM50006952; ZINC29486259; AKOS024458570; NCGC00024664-02; NCGC00024664-03; B6361; SR-01000597636; J-006367; SR-01000597636-1; BRD-K62581435-001-01-2; BRD-K62581435-001-02-0; Q27195293
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| Activity |
Ki ~ 100000 nM
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[19] | |||
| Compound Name |
5-[(1S)-2-[[(2R)-Heptan-2-yl]amino]-1-hydroxyethyl]benzene-1,3-diol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4110387; BDBM206777; (S,R)- 6; US9492405, (S,R)-6
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| Activity |
Ki ~ 100000 nM
|
[11] | |||
| Compound Name |
2-Amino-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-phenylacetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL550743; BDBM50293416; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-amino-2-phenylacetanilide
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| Activity |
EC50 ~ 100000 nM
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[20] | |||
| Compound Name |
3-[2-[4-Phenyl-1-piperazinyl]ethyl]-1H-pyrimido[5,4-b]indole-2,4(3H,5H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL51963; BDBM50006950; 2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-4,9-dihydro-2,4,9-triaza-fluorene-1,3-dione
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| Activity |
Ki ~ 100000 nM
|
[19] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-(4-methoxyphenyl)acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL551350; BDBM50293422; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(4-methoxyphenyl)acetanilide
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| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-(2-methoxyphenyl)thiourea;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203995
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| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-pyridin-3-yloxypropyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL466713; BDBM50259166; (S)-4''-(2-{[2-Hydroxy-3-(2-benzimidazolon-4-yloxy)-propyl]amino}ethyl)-2-(2-pyridyl)-acetanilide
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| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-[4-[2-[[(2S)-3-(9H-Carbazol-4-yloxy)-2-hydroxypropyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL466923; BDBM50259205
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| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(S)-1-[(2-{1-[(1-Benzylimidazol-2-yl)acetyl]-1,2,3,4-tetrahydroquinolin-6-yl}ethyl)-amino]-3-phenoxy-2-propanol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL512099; BDBM50259522
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
1-Cyclohexyl-3-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203988
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-quinolin-2-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL552089; BDBM50293430; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(quinolin-2-yl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-naphthalen-1-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL564556; BDBM50293423; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(1-naphthyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-phenylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL550746; BDBM50293434; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-phenylacetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2,2-diphenylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551831; BDBM50293414; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2,2-diphenylacetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Methyl 4-[[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]carbamothioylamino]benzoate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203999
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(1H-indol-4-yloxy)propyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466704; BDBM50259124
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-(2-methoxyphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL557269; BDBM50293420; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(2-methoxyphenyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
3-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-1,5-dimethylpyrimido[5,4-b]indole-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL54716; Biomol-NT_000126; BPBio1_000266; CTK4B8521; DTXSID20392297; BDBM50006953; NCGC00163149-01; NCGC00163149-02
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[19] | |||
| Compound Name |
2-Hydroxy-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-phenylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551832; BDBM50293415; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-hydroxy-2-phenylacetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[6-(6,7-Dihydroxy-1,2,3,4-tetrahydro-isoquinolin-1-ylmethoxy)-naphthalen-2-yl]-4-(3-hexyl-ureido)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76403; SCHEMBL8199559; BDBM50093036
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-phenylurea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1204383
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
5-[(R)-1-Hydroxy-2-[[(alphaS)-alpha-propyl-4-methoxyphenethyl]amino]ethyl]resorcinol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3099664; BDBM50495018
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[22] | |||
| Compound Name |
1-(4-Chlorophenyl)-3-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2448072
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-2-pyridin-2-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466515; BDBM50259165; (S)-4''-(2-{[2-Hydroxy-3-phenoxypropyl]amino}ethyl)-2-(2-pyridyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-pyrazin-2-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL552497; BDBM50293433; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(pyrazin-2-yl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
5-[(R)-1-Hydroxy-2-[[(alphaS)-alpha-isopropyl-4-methoxyphenethyl]amino]ethyl]resorcinol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3099661; BDBM50495021
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[22] | |||
| Compound Name |
2-(1-Benzylimidazol-4-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467301; BDBM50259321; (S)-4''-{2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl}-2-(1-benzylimidazol-4-yl)-acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
Chembl4173735
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288200
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
2-(2-Chlorophenyl)-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL564544; BDBM50293417; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(2-chlorophenyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-(2-nitrophenyl)thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203994
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[3'-(6,7-Dihydroxy-1,2,3,4-tetrahydroisoquinoline-1-ylmethyl)-4-biphenylyl]-4-(3-hexylureido)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL74860; SCHEMBL8191610; BDBM50093042
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[21] | |||
| Compound Name |
1-(4-Fluorophenyl)-3-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1204001
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(3-Chlorophenyl)-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561348; BDBM50293418; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(3-chlorophenyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-(4-iodophenyl)thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1204002
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-2-(1-phenylimidazol-2-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467082; BDBM50259254; (S)-4''-{2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl}-2-(1-phenylimidazol-2-yl)-acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-thiophen-3-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551892; BDBM50293427; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(3-thenyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
1-(3-Chlorophenyl)-3-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2448074
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(4-Chlorophenyl)-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL563810; BDBM50293419; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(4-chlorophenyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-2-(6-phenylmethoxypyridin-2-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466467; BDBM50259252; (S)-4''-{2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl}-2-(6-benzyloxy-2-pyridyl)-acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(S,R)-(+)-5-[1-Hydroxy-2-(1-methylhexylamino)ethyl]-1,3-benzenediol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL229616; BDBM50213113
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[10] | |||
| Compound Name |
4-[(S)-2-Hydroxy-3-[1-(3,4-dimethoxyphenylsulfonyl)-4-piperidinylamino]propoxy]-9H-carbazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL71948; SCHEMBL6983825; BDBM50129450; (2S)-1-(9H-carbazol-4-yloxy)-3-[[1-(3,4-dimethoxyphenyl)sulfonylpiperidin-4-yl]amino]propan-2-ol; (S)-1-(9H-Carbazol-4-yloxy)-3-[1-(3,4-dimethoxy-benzenesulfonyl)-piperidin-4-ylamino]-propan-2-ol
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-phenylthiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203993; SCHEMBL8588198
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
3-[2-[4-(4-Methoxyphenyl)-1-piperazinyl]ethyl]-1H-pyrimido[5,4-b]indole-2,4(3H,5H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL52473; BDBM50006955; 2-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-4,9-dihydro-2,4,9-triaza-fluorene-1,3-dione
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[19] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-pyridin-4-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561693; BDBM50293429; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(4-pyridyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-(4-nitrophenyl)thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203990
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-naphthalen-2-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561291; BDBM50293424; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(2-naphthyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
3-(Butyl-4-{4-[((2R)-2-hydroxy-2-{4-hydroxy-3-[(methylsulfonyl)amino]phenyl}-ethyl)amino]-1-piperidineyl}anilino)-3-oxopropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL418600; SCHEMBL6074003; BDBM50098658
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[3] | |||
| Compound Name |
5-[(R)-1-Hydroxy-2-[[(alphaR)-alpha-isopropyl-4-methoxyphenethyl]amino]ethyl]resorcinol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3099662; BDBM50495014
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[22] | |||
| Compound Name |
2-(4,6-Dimethylpyridin-2-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466925; BDBM50259207; (S)-4''-(2-{[2-Hydroxy-3-phenoxypropyl]amino}ethyl)-2-(4,6-dimethyl-2-pyridyl)-acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-(2-phenylethyl)thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203987
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
4-{(S)-3-[1-(3,4-Dimethoxy-benzenesulfonyl)-piperidin-4-ylamino]-2-hydroxy-propoxy}-1,3-dihydro-benzoimidazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306430; SCHEMBL6984549; BDBM50129441
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-2-(1H-imidazol-2-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466879; BDBM50259253; (S)-4''-{2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl}-2-(1H-imidazol-2-yl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
Chembl4174295
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288202
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
5-[(S)-1-Hydroxy-2-(4-methoxyphenethylamino)ethyl]resorcinol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3099658; BDBM50495016
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[22] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-(4-sulfamoylphenyl)thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203991
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(1-Benzylimidazol-2-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]propyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466088; BDBM50259366; (S)-4''-{2-[(2-Hydroxy-3-phenoxypropyl)amino]propyl}-2-(1-benzylimidazol-2-yl)-acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
4-[1-Hydroxy-2-[2-[4-[2-[[2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]ethyl]phenyl]ethylamino]ethyl]-2-(hydroxymethyl)phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1940811; BDBM50419633
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[7] | |||
| Compound Name |
Phenyl N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]carbamate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203992
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
3-[2-[4-(2-Chlorophenyl)-1-piperazinyl]ethyl]-1H-pyrimido[5,4-b]indole-2,4(3H,5H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL57163; SCHEMBL12648691; BDBM50006954; 2-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-4,9-dihydro-2,4,9-triaza-fluorene-1,3-dione; 3-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-1,5-dihydro-pyrimido[5,4-b]indole-2,4-dione
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[19] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-pyrimidin-2-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562154; BDBM50293432; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(pyrimidin-2-yl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
2-[1-[(4-Chlorophenyl)methyl]imidazol-2-yl]-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467502; BDBM50259322; (S)-4''-{2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl}-2-[1-(4-chlorobenzyl)imidazol-2-yl]acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203997
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Chembl4166379
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288248
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-isoquinolin-3-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562153; BDBM50293431; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(isoquinolin-3-yl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
Chembl4160295
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288183
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-2-(3-methylpyridin-2-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466924; BDBM50259206; (S)-4''-(2-{[2-Hydroxy-3-phenoxypropyl]amino}ethyl)-2-(3-methyl-2-pyridyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(S)-N-(4-(2-(2-Hydroxy-3-(4-hydroxyphenoxy)propylamino)ethyl)phenyl)-2-(pyridin-2-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466705; BDBM50259125; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(2-pyridyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
2-(1-Benzylbenzimidazol-2-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467298; BDBM50259320; (S)-4''-(2-{[2-Hydroxy-3-phenoxypropyl]amino}ethyl)-2-(1-benzyl-benzimidazol-2-yl)-acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-(3-methoxyphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561211; BDBM50293421; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(3-methoxyphenyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
2-(1-Benzylimidazol-2-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467083; BDBM50259255; (S)-4''-{2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl}-2-(1-benzylimidazol-2-yl)-acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
Chembl4175397
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288194
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-thiophen-2-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL539226; BDBM50293426; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(2-thenyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
2-(1-Benzylimidazol-2-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-N-propylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467117; BDBM50259469; (S)-N-Propyl-4''-{2-[(2-hydroxy-3-phenoxypropyl)-amino]ethyl}-2-(1-benzylimidazol-2-yl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
3-[2-[4-(4-Chlorophenyl)-1-piperazinyl]ethyl]-1H-pyrimido[5,4-b]indole-2,4(3H,5H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55338; BDBM50006951; 2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-4,9-dihydro-2,4,9-triaza-fluorene-1,3-dione
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[19] | |||
| Compound Name |
4-[(S)-2-Hydroxy-3-[1-(4-methoxyphenylsulfonyl)-4-piperidinylamino]propoxy]-9H-carbazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306423; SCHEMBL6983938; BDBM50129442; (2S)-1-(9H-carbazol-4-yloxy)-3-[[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]amino]propan-2-ol; (S)-1-(9H-Carbazol-4-yloxy)-3-[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylamino]-propan-2-ol
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
(2S)-1-[2-(4-Anilinophenyl)ethylamino]-3-phenoxypropan-2-ol;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1204004
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
1-Cyano-2-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-phenylguanidine;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1204005
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
2-(6-Chloropyridin-2-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466726; BDBM50259208; (S)-4''-{2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl}-2-(6-chloro-2-pyridyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
2-[1-[(4-Bromophenyl)methyl]imidazol-2-yl]-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467102; BDBM50259364; (S)-4''-{2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl}-2-[1-(4-bromobenzyl)imidazol-2-yl]acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
Chembl4167532
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288201
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-(4-methoxyphenyl)thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1204007
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Chembl4174691
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288172
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-[2-oxo-3-(3-oxo-3-pyrrolidin-1-yl-propyl)-imidazolidin-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL79915; BDBM50075909
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[4] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-(4-methylphenyl)thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1204000
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
1-(4-Bromophenyl)-3-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203998
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Chembl4162920
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288190
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
Chembl4170536
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288198
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
Chembl4167473
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288182
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
1-Benzyl-3-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1204006
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-2-[1-(naphthalen-2-ylmethyl)imidazol-2-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467103; BDBM50259365; (S)-4''-{2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl}-2-[1-(2-naphtylmethyl)imidazol-2-yl]acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
4-{(S)-2-Hydroxy-3-[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylamino]-propoxy}-1,3-dihydro-benzoimidazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL68685; SCHEMBL6980370; BDBM50129443
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
Chembl4170908
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288310
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
(S)-N-(4-(2-(2-Hydroxy-3-phenoxypropylamino)ethyl)phenyl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL563872; BDBM50295318
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL417613; SCHEMBL9269408; BDBM50070132; L-739574; (S)-N-(4-(2-(2-hydroxy-3-(4-hydroxyphenoxy)propylamino)ethyl)phenyl)benzenesulfonamide; N-(4-{2-[(S)-2-Hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenyl)-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Chembl4170860
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50288191
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[18] | |||
| Compound Name |
2-(1-Benzylimidazol-2-yl)-N-[4-[2-[[(2S)-2-hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-N-methylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467116; BDBM50259468; (S)-N-Methyl-4''-{2-[(2-hydroxy-3-phenoxypropyl)-amino]ethyl}-2-(1-benzylimidazol-2-yl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-[4-[2-[[(2S)-2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-2-pyridin-3-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561818; BDBM50293428; (S)-4''-(2-{[2-Hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(3-pyridyl)acetanilide
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
4-[(S)-2-Hydroxy-3-[1-(4-methoxyphenylsulfonyl)-4-piperidinylamino]propoxy]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL71348; SCHEMBL6984583; BDBM50129445; 4-[(2S)-2-hydroxy-3-[[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]amino]propoxy]phenol; 4-{(S)-2-Hydroxy-3-[1-(4-methoxy-benzenesulfonyl)-piperidin-4-ylamino]-propoxy}-phenol
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
1-[4-[2-[[(2S)-2-Hydroxy-3-phenoxypropyl]amino]ethyl]phenyl]-3-(3-methoxyphenyl)thiourea;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1203996
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(S)-1-[1-(4-Butoxy-benzenesulfonyl)-piperidin-4-ylamino]-3-(9H-carbazol-4-yloxy)-propan-2-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL70230; SCHEMBL6980970; BDBM50129452; (2S)-1-[[1-(4-butoxyphenyl)sulfonylpiperidin-4-yl]amino]-3-(9H-carbazol-4-yloxy)propan-2-ol
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
2-(Hydroxymethyl)-4-[1-hydroxy-2-[2-[4-[4-(3-phenylpropyl)piperidin-1-yl]phenyl]ethylamino]ethyl]phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290976; BDBM50018595
Click to Show/Hide
|
||||
| Activity |
Ki = 199526.23 nM
|
[24] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 11 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
4-[1-Hydroxy-2-[[3-[[2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]-2,2-dimethylpropyl]amino]ethyl]-2-(hydroxymethyl)phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1940684; BDBM50419657
Click to Show/Hide
|
||||
| Activity |
IC50 = 251188.64 nM
|
[7] | |||
| Compound Name |
Chembl4217119
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50454558
Click to Show/Hide
|
||||
| Activity |
Ki = 268000 nM
|
[9] | |||
| Compound Name |
3-(Hydroxymethyl)-5-methyl-2-pentyl-1-phenethyl-1H-indole-6-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL250740; SCHEMBL4431988; BDBM50231889
Click to Show/Hide
|
||||
| Activity |
IC50 = 280000 nM
|
[25] | |||
| Compound Name |
N-Methyl-4-(1,3-thiazol-2-yl)benzylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4202934; N-methyl-1-[4-(1,3-thiazol-2-yl)phenyl]methanamine; methyl({[4-(1,3-thiazol-2-yl)phenyl]methyl})amine; SCHEMBL22207772; CTK5G1214; DTXSID30594508; BDBM50454559; MFCD09025836; SBB093351; ZINC12370253; DB-010223; N-Methyl-4-(1,3-thaizol-2-y)benzyalmine; FT-0706989; Y4556; Benzenemethanamine,N-methyl-4-(2-thiazolyl)-; methyl[(4-(1,3-thiazol-2-yl)phenyl)methyl]amine; J-523655
Click to Show/Hide
|
||||
| Activity |
Ki = 365000 nM
|
[9] | |||
| Compound Name |
1-(Benzo[b]thiophen-2-yl)-N-methylmethanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-(1-benzothiophen-2-yl)-N-methylmethanamine; CHEMBL3358195; 2-(Methylaminomethyl)benzothiophene; (1-BENZOTHIEN-2-YLMETHYL)METHYLAMINE; F3145-1892; TimTec1_002560; Oprea1_368216; Oprea1_633790; SCHEMBL1254283; ZINC64947; DTXSID20351182; ALBB-015188; BDBM50037773; MFCD03698066; STK045938; AKOS000530132; Benzo[b]thiophen-2-ylmethylmethylamine; MCULE-6356407325; NCGC00173990-01; 1-Benzothien-2-yl-N-methylmethanamine HCl; Benzo[b]thiophene-2-methanamine, N-methyl-; DB-068838; FT-0734380; Y-0748; 1-(1-benzothien-2-yl)-N-methylmethanamine hydrochloride
Click to Show/Hide
|
||||
| Activity |
Ki = 373000 nM
|
[9] | |||
| Compound Name |
2-(4-Carboxy-1-hydroxybutyl)-6-methyl-3-phenethyl-1H-indole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252077; BDBM50231892
Click to Show/Hide
|
||||
| Activity |
IC50 = 777000 nM
|
[25] | |||
| Compound Name |
1-(2-Piperidin-1-ylethoxy)-6H-benzo[b][1]benzothiepin-5-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1626178; 6-[2-(1-piperidinyl)ethoxy]dibenzo[b,f]thiepin-10(11H)-one; Oprea1_151330; AE-641/30109061; ZINC726335; BDBM50389825; AKOS005066465
Click to Show/Hide
|
||||
| Activity |
Ki = 794328.23 nM
|
[26] | |||
| Compound Name |
2-((2-Carboxyethyl)carbamoyl)-6-methyl-3-phenethyl-1H-indole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252273; BDBM50231890
Click to Show/Hide
|
||||
| Activity |
IC50 = 820000 nM
|
[25] | |||
| Compound Name |
1-(4-Chlorophenyl)ethanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-(4-Chlorophenyl)ethylamine; 4-Chloro-alpha-methylbenzylamine; 4-Chloro-a-methylbenzylamine; 1-(4-chlorophenyl)ethan-1-amine; CHEMBL4214761; 1-(4-chlorophenyl)-1-ethanamine; Clophar; 4-chloro-alpha-methyl benzylamine; NSC42452; ACMC-20amkz; ACMC-20apje; ACMC-209jma; 4-Chloro-methylbenzylamine; SCHEMBL177057; 1-(4-chlorophenyl)-ethylamine; p-chloro-alpha-methylbenzylamine; 1-(4-chloro-phenyl)-ethylamine; 1-(4-chlorophenyl)-ethyl-amine; CTK6A5010; KS-00003AYR; ALBB-002133; BCP09416; EINECS 228-576-0; (+/-)1-(4-chlorophenyl)ethylamine; BBL017845; BDBM50454557; MFCD00044766; NSC-42452; SBB004019; STK486975; 1-(4-Chlorophenyl)ethylamine, 97%; (+/-) 1-(4-chlorophenyl)ethylamine; (+/-)-1-(4-chlorophenyl)ethylamine; AKOS000264390; AKOS016042318; racemic 1-(4-chloro-phenyl)ethylamine; AS02836; CM13559; MCULE-9585055548; racemic 1-(4-chloro-phenyl)-ethylamine; racemic 1 -(4-chloro-phenyl)-ethylamine; SC-86743; (+/-)-4-chloro-(alpha-methyl)benzylamine; 2-FLUORO-2-DEOXY-D-GALACTOPYRANOSE; DB-054361; BB 0254687; CS-0042334; FT-0605114; FT-0605284; FT-0636081; ST45141124; Y9670; 6H-029; C-5454; (AlphaR)-4-chloro-alpha-methylbenzenemethanamine; J-501731; W-110103; 5-AMINO-BENZOFURAN-2-CARBOXYLICACIDMETHYLESTER; Benzenemethanamine, 4-chloro-.alpha.-methyl-, (.alpha.S)-
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[9] | |||
| Compound Name |
Chembl4213668
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50454552
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[9] | |||
| Compound Name |
2-(1-Hydroxypentyl)-6-methyl-3-(2-phenylethyl)-1H-Indole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL403296; SCHEMBL1913466; DTXSID50468136; 2-(1-hydroxypentyl)-6-methyl-3-phenethyl-1H-indole-5-carboxylic Acid; BDBM50231891; MFCD27978011; FT-0669532
Click to Show/Hide
|
||||
| Activity |
IC50 = 1540000 nM
|
[25] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Structure-guided development of dual 2 adrenergic/dopamine D2 receptor agonists. Bioorg Med Chem. 2016 Jun 15;24(12):2641-53. | ||||
| REF 2 | Structural basis of the selectivity of the beta(2)-adrenergic receptor for fluorinated catecholamines. Bioorg Med Chem. 2009 Dec 1;17(23):7987-92. | ||||
| REF 3 | (4-Piperidin-1-yl)phenyl amides: potent and selective human beta(3) agonists. J Med Chem. 2001 Apr 26;44(9):1456-66. | ||||
| REF 4 | Human beta3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides. Bioorg Med Chem Lett. 1999 Mar 8;9(5):755-8. | ||||
| REF 5 | 3-Pyridylethanolamines: potent and selective human beta 3 adrenergic receptor agonists. Bioorg Med Chem Lett. 1998 Nov 3;8(21):3087-92. | ||||
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