Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T65116 | Target Info | |||
| Target Name | Ecto-5'-nucleotidase (CD73) | ||||
| Synonyms |
NT5; CD73 antigen; 5'-nucleotidase; 5'-NT
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| Target Type | Clinical trial Target | ||||
| Gene Name | NT5E | ||||
| Biochemical Class | Phosphoric monoester hydrolase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 2 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Chembl4276670
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL19100539; BDBM50470565
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| Activity |
IC50 = 111900 nM
|
[1] | |||
| Compound Name |
Chembl4283386
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|
Investigative | Compound Info | ||
| Synonyms |
BDBM50470563
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| Activity |
IC50 = 147100 nM
|
[1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | CD73 inhibition by purine cytotoxic nucleoside analogue-based diphosphonates. Eur J Med Chem. 2018 Sep 5;157:1051-1055. | ||||
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