Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T68251 | Target Info | |||
| Target Name | Matrix metalloproteinase-2 (MMP-2) | ||||
| Synonyms |
TBE-1; Matrix metalloproteinase 2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase
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|
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| Target Type | Successful Target | ||||
| Gene Name | MMP2 | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 305 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Clodronate
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|
Approved | Compound Info | ||
| Synonyms |
Bonefos; Clodronsaeure; Dichloromethanediphosphonate; Dichloromethylenebisphosphonate; Methanedichlorodiphosphonate; Acide clodronique; Acido clodronico; Acidum clodronicum; Clodronic Acid; Dichloromethanediphosphonic acid; Dichloromethylene Biphosphonate; Dichloromethylene Diphosphonate; Dichloromethylidene diphosphonate; Liposomes containing clodronic acid; Methanedichlorodiphosphonic acid; Acid, Clodronic; Acid, Dichloromethanediphosphonic; Acide clodronique [INN-French]; Acido clodronico [INN-Spanish]; Acidum clodronicum [INN-Latin]; Biphosphonate, Dichloromethylene; Bonefos (TN); Clodron (TN); Diphosphonate, Dichloromethane; Diphosphonate, Dichloromethylene; Disodium, Clodronate; Loron (TN); Sodium, Clodronate; [dichloro(phosphono)methyl]phosphonic acid; Clodronic acid (USAN/INN); Clodronic acid [USAN:BAN:INN]; Dichlormethylen-bis(phosphonsaeure); Dichloromethylene-1,1-bisphosphonic acid; Dichloromethylene-1,1-diphosphonic acid; Phosphonic acid, (dichloromethylene)di-(8CI); (Dichloro-phosphono-methyl)-phosphonic acid; (Dichloromethylene)bisphosphonic acid; (Dichloromethylene)diphosphonic acid; (Lip-C); (dichloromethanediyl)bis(phosphonic acid)
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| Activity |
IC50 = 145000 nM
|
[1] | |||
| Compound Name |
US9206139, 4
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|
Patented | Compound Info | ||
| Synonyms |
CHEMBL3955404; SCHEMBL15692527; BDBM194645; US9206139, 4
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| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
5-Methyl-5-phenyl-pyrimidine-2,4,6-trione
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Investigative | Compound Info | ||
| Synonyms |
Heptobarbital; Mephebarbital; Eudan; Phenylmethylbarbituric acid; Rutonal; Methylphenylbarbital; 5-Methyl-5-phenylbarbituric acid; 5-Methyl-5-phenylbarbityric acid; 76-94-8; 5-Phenyl-5-methylbarbituric acid; NSC 80543; Barbituric acid, 5-methyl-5-phenyl-; UNII-GFR227X6YY; 5-Methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione; EINECS 200-994-8; BRN 0201825; GFR227X6YY; CHEMBL329617; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-methyl-5-phenyl-; 5-methyl-5-phenyl-barbituric acid; C11H10N2O3; 5-methyl-5-phenyl-1,3-diazinane-2,4,6-trione
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| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
Methotrexate gamma-L-phenylalaninehydroxamic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL396296; methotrexate gamma-L-phenylalaninehydroxamic acid
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| Activity |
IC50 = 60000 nM
|
[4] | |||
| Compound Name |
UK-383367
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Investigative | Compound Info | ||
| Synonyms |
UK 383367; 348622-88-8; UK-383367; CHEMBL226630; 5-[(1R)-4-Cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl]-1,2,4-oxadiazole-3-carboxamide; (R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxamide; ARJCBSRIPGJMAD-LLVKDONJSA-N; UK383367; 5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-1,2,4-oxadiazole-3-carboxamide; MLS006011234; SCHEMBL6430715; CTK8F1316; SYN3014; DTXSID30431303; MolPort-016-633-322; ZINC3818556; s2224; BDBM50216795; AKOS024458022; SB19579; RL03300; CS-0414
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| Activity |
IC50 ~ 60000 nM
|
[5] | |||
| Compound Name |
Folate gamma-L-phenylalaninehydroxamic acid
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Investigative | Compound Info | ||
| Activity |
IC50 = 65000 nM
|
[4] | |||
| Compound Name |
2-(4-chlorobenzyloxyamino)-N-hydroxypropanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL228229; 2-(4-chlorobenzyloxyamino)-N-hydroxypropanamide
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| Activity |
IC50 = 68000 nM
|
[6] | |||
| Compound Name |
2-(4-chlorobenzyloxyamino)-N-hydroxyhexanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL388309; 2-(4-chlorobenzyloxyamino)-N-hydroxyhexanamide
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| Activity |
IC50 = 81800 nM
|
[6] | |||
| Compound Name |
2-(benzyloxyamino)-N-hydroxyacetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL226149; 2-(benzyloxyamino)-N-hydroxyacetamide
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| Activity |
IC50 = 94000 nM
|
[6] | |||
| Compound Name |
PF-00356231
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Investigative | Compound Info | ||
| Synonyms |
PF-00356231; CHEMBL508461; (2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARBOXAMIDO)(PHENYL)PROPANOIC ACID; 3-PHENYL-3-({[4-(4-PYRIDIN-4-YLPHENYL)THIEN-2-YL]CARBONYL}AMINO)PROPANOIC ACID; 1utz; AC1L9MIX; SCHEMBL8298104; MolPort-042-665-664; ZINC6744035; BDBM50264813; DB03367; NCGC00386512-01; (3R)-3-phenyl-3-({4-[4-(pyridin-4-yl)phenyl]thiophen-2-yl}formamido)propanoic acid; (3R)-3-phenyl-3-({[4-(4-pyridin-4-ylphenyl)thiophen-2-yl]carbonyl}amino)propanoic acid
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
N1,N3-bis(3-methoxybenzyl)isophthalamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL605201; N1,N3-bis(3-methoxybenzyl)isophthalamide; SCHEMBL5332068
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| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(biphenyl-3-ylamino)methylenediphosphonic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL55371; AC1NQQUY; (biphenyl-3-ylamino)methylenediphosphonic acid; BPH-218; NSC725581; BDBM50138040; ZINC13532369; NSC-725581; [(3-phenylanilino)-phosphonomethyl]phosphonic acid; [(3-phenylanilino)-phosphono-methyl]phosphonic acid; [(Biphenyl-3-ylamino)-phosphono-methyl]-phosphonic acid; (Biphenyl-3-yl)- aminomethylene-1,1-bisphosphonate (dihydrate); Phosphonic acid, [([1,1'-biphenyl]-3-ylamino)methylene]bis-
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| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
OXYQUINOLINE
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Investigative | Compound Info | ||
| Synonyms |
8-HYDROXYQUINOLINE; quinolin-8-ol; 8-quinolinol; 148-24-3; Oxyquinoline; Oxine; Quinophenol; 8-Quinol; 8-Oxyquinoline; Phenopyridine; Oxychinolin; Bioquin; Oxybenzopyridine; Oxin; Hydroxybenzopyridine; 1-Azanaphthalene-8-ol; Tumex; 8-Chinolinol; 8-Hydroxychinolin; 8-OQ; 8-Hydroxy-chinolin; Fennosan H 30; Fennosan; o-Oxychinolin; 8-Oxychinolin; Usaf ek-794; Fennosan HF-15; NCI-C55298; NSC 2039; Oxyquinoline [USAN]; Caswell No. 719; Oxoquinoline; 8-Chinolinol [Czech]; o-Oxychinolin [German]; Quinoline, 8-hydroxy-; NSC 615011; UNII-5UTX5635HP
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| Activity |
IC50 = 130000 nM
|
[10] | |||
| Compound Name |
2-(4-chlorobenzyloxyamino)-N-hydroxyacetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL227566; 2-(4-chlorobenzyloxyamino)-N-hydroxyacetamide
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| Activity |
IC50 = 137000 nM
|
[6] | |||
| Compound Name |
TROPOLONE
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Investigative | Compound Info | ||
| Synonyms |
Tropolone; 533-75-5; 2-Hydroxycyclohepta-2,4,6-trienone; Purpurocatechol; 2-Hydroxy-2,4,6-cycloheptatrien-1-one; 2,4,6-Cycloheptatrien-1-one, 2-hydroxy-; 2-hydroxycyclohepta-2,4,6-trien-1-one; 2-Hydroxytropone; 2-Hydroxy-2,4,6-cycloheptatrienone; UNII-7L6DL16P1T; Tropolone, 98%; CCRIS 6609; NSC89303; EINECS 208-577-2; NSC 89303; BRN 1904978; CHEMBL121188; 7L6DL16P1T; CHEBI:79966; MDYOLVRUBBJPFM-UHFFFAOYSA-N; MFCD00004158; Tropomyosins; 0TR; PubChem6330; NCIMech_000829; AC1L1VY5; DSSTox_RID_83491; DSSTox_CID_29376; DSSTox_GSID_49416
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| Activity |
IC50 = 146000 nM
|
[10] | |||
| Compound Name |
2-(benzyloxyamino)-N-hydroxy-3-methylpentanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL228231; 2-(benzyloxyamino)-N-hydroxy-3-methylpentanamide
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| Activity |
IC50 = 151000 nM
|
[6] | |||
| Compound Name |
2-Cinnamamido-N4-hexyl-N1-hydroxysuccinamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL595209; 2-Cinnamamido-N4-hexyl-N1-hydroxysuccinamide
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| Activity |
IC50 = 178600 nM
|
[11] | |||
| Compound Name |
2-Cinnamamido-N1-hydroxy-N4-pentylsuccinamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL596560; 2-Cinnamamido-N1-hydroxy-N4-pentylsuccinamide
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| Activity |
IC50 = 196500 nM
|
[11] | |||
| Compound Name |
N-(1,1':4',1''-Terbenzene-4-ylmethyl)-3-hydroxy-4-oxo-6-methyl-4H-pyran-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL489603; AM-6; SCHEMBL13208686; BDBM50264772; 3-Hydroxy-6-methyl-4-oxo-4H-pyran-2-carboxylic acid ([1,1'';4'',1'''']terphenyl-4-ylmethyl)-amide
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(Dibutylamino)carbonylphosphonic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL96438; BDBM50146804
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| Activity |
IC50 = 50000 nM
|
[12] | |||
| Compound Name |
N-Benzhydryl-2-[1-benzhydryl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL97454; BDBM50081801
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| Activity |
IC50 = 50000 nM
|
[13] | |||
| Compound Name |
1,5-Dimethyl-5-(4-phenoxyphenyl)hexahydropyrimidine-2,4,6-trione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL366956; SCHEMBL6810545; BDBM50099124; 1,5-Dimethyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trione; 1,5-dimethyl-5-(4-phenoxyphenyl)-1,3-diazinane-2,4,6-trione
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
(2R,3R)-N-(2-(4-Benzylthiophen-2-yl)ethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL602949; SCHEMBL8217850; BDBM50309154
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| Activity |
Ki ~ 50000 nM
|
[14] | |||
| Compound Name |
N-[(1S,2S)-2-Hydroxycyclopentyl]-4-phenoxybenzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380397; BDBM50433870
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| Activity |
Ki = 50000 nM
|
[15] | |||
| Compound Name |
4-(4-Methylphenoxy)-N-(4-pyridinylmethyl)benzenecarboxamide
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Investigative | Compound Info | ||
| Synonyms |
MLS000755676; SMR000337350; 4-(4-methylphenoxy)-N-[(pyridin-4-yl)methyl]benzamide; 4-(4-methylphenoxy)-N-(pyridin-4-ylmethyl)benzamide; CHEMBL1427458; BDBM46421; cid_4358655; HMS2618P15; KS-00003O5G; ZINC4054502; AKOS005107358; MCULE-5269053313; MS-1279; 4-(4-methylphenoxy)-N-(4-pyridylmethyl)benzamide
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| Activity |
IC50 = 50118.72 nM
|
[16] | |||
| Compound Name |
(R)-5-(6-Cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N-methyl-N-(pyridin-2-ylmethyl)-1,2,4-oxadiazole-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL482341; SCHEMBL6429969; BDBM50256096
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| Activity |
IC50 = 50500 nM
|
[5] | |||
| Compound Name |
N6-[(Benzyloxy)carbonyl]-N2-cinnamoyl-L-lysine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL483320; BDBM50271856
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| Activity |
IC50 = 50500 nM
|
[17] | |||
| Compound Name |
N-Butyl-2-[1-[2-(4-fluoro-phenyl)-ethyl]-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL95560; BDBM50081788
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| Activity |
IC50 = 51000 nM
|
[13] | |||
| Compound Name |
N-[3,3-Dimethyl-1-oxo-1-(1-phenylethylamino)butan-2-yl]-N'-hydroxy-2-[3-[4-phenyl-3-(trifluoromethyl)phenyl]propyl]butanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3828582; BDBM50187412
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| Activity |
IC50 = 51999.6 nM
|
[18] | |||
| Compound Name |
4-Phenylbutyl[1-(4-phenylbutyl)-3-(4-phenoxyphenyl)ureidoacetyl]aminoacetohydroximic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL316884; BDBM50081780
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| Activity |
IC50 = 52000 nM
|
[13] | |||
| Compound Name |
[(4-Bromophenyl)sulfonyl-phosphonomethyl]phosphonic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3291004; BDBM50018629; ZINC169351253
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| Activity |
IC50 = 52000 nM
|
[19] | |||
| Compound Name |
(2R)-N-[(2S)-3,3-Dimethyl-1-oxo-1-[[(1R)-1-phenylethyl]amino]butan-2-yl]-N'-hydroxy-2-[3-[4-phenyl-3-(trifluoromethyl)phenyl]propyl]butanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL345305; BDBM50097269
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| Activity |
IC50 = 52000 nM
|
[20] | |||
| Compound Name |
(R)-5-(4-Chlorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL489826; BDBM50267918
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| Activity |
IC50 = 52300 nM
|
[21] | |||
| Compound Name |
(2S)-N-[(2S,3S)-2-Amino-3-hydroxy-3-(4-iodophenyl)propyl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819450; BDBM50351046
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| Activity |
IC50 = 52700 nM
|
[22] | |||
| Compound Name |
(R)-5-(4-Chloro-2-fluorobenzylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL514379; BDBM50267320
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| Activity |
IC50 = 52800 nM
|
[21] | |||
| Compound Name |
Chembl4206592
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Investigative | Compound Info | ||
| Synonyms |
BDBM50457771
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| Activity |
IC50 = 53670 nM
|
[23] | |||
| Compound Name |
N-Sec-Butyl-2-[1-butyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL420447; BDBM50081783
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| Activity |
IC50 = 54000 nM
|
[13] | |||
| Compound Name |
Chembl4208066
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Investigative | Compound Info | ||
| Synonyms |
BDBM50457773
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| Activity |
IC50 = 54180 nM
|
[23] | |||
| Compound Name |
(R)-5-(4-Bromophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL523279; BDBM50267919
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| Activity |
IC50 = 54400 nM
|
[21] | |||
| Compound Name |
N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(tetrahydro-thiopyran-4-ylidenemethyl)-ethyl]-formamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL98202; SCHEMBL3881504; BDBM50146475
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| Activity |
IC50 = 55000 nM
|
[24] | |||
| Compound Name |
(4R)-5-Oxo-5-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]-4-[(3,4,5-trimethoxybenzoyl)amino]pentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL486063; BDBM50267841
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| Activity |
IC50 = 55300 nM
|
[21] | |||
| Compound Name |
(2S)-2-[[2-(3-Methyl-2-oxoquinoxalin-1-yl)acetyl]amino]-3-phenyl-N-propylpropanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL603452; BDBM50306923; (S)-2-(2-(3-Methyl-2-oxoquinoxalin-1(2H)-yl)acetamido)-3-phenyl-N-propylpropan-amide
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| Activity |
IC50 = 56600 nM
|
[25] | |||
| Compound Name |
2-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL254239; BDBM50227569
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| Activity |
IC50 = 57000 nM
|
[26] | |||
| Compound Name |
N-[1-(4'-Cyano-4-biphenylyloxymethyl)-2-(2,5-dioxo-3,4,4-trimethylimidazolidine-1-yl)ethyl]formhydroxamic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL288067; SCHEMBL7505333; BDBM50100902
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| Activity |
IC50 = 58000 nM
|
[27] | |||
| Compound Name |
2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL585376; BDBM50299069
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| Activity |
IC50 = 58000 nM
|
[28] | |||
| Compound Name |
N-{2-[(4'-Cyano-1,1'-biphenyl-4-YL)oxy]ethyl}-N'-hydroxy-N-methylurea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL200435; BDBM50175780; DB06971; Q27095882; 1-{2-[(4'-cyanobiphenyl-4-yl)oxy]ethyl}-3-hydroxy-1-methylurea; N-{2-[(4''-cyano-1,1''-biphenyl-4-yl)oxy]ethyl}-N''-hydroxy-N-methylurea
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| Activity |
IC50 = 58000 nM
|
[29] | |||
| Compound Name |
(S)-2-(2-(3-Methyl-2-oxoquinoxalin-1(2H)-yl)acetamido)-N,3-diphenylpropanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL604328; BDBM50306912
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| Activity |
IC50 = 58140 nM
|
[25] | |||
| Compound Name |
2,6-Dichloro-N'-[2-(3-methyl-2-oxo-quinoxalin-1-yl)acetyl]benzohydrazide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775574; BDBM50155279
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| Activity |
IC50 = 58220 nM
|
[30] | |||
| Compound Name |
(S,E)-5-(4-Chlorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL516281; BDBM50267340
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| Activity |
IC50 = 59900 nM
|
[31] | |||
| Compound Name |
N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(tetrahydro-pyran-4-ylidenemethyl)-ethyl]-formamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL99045; SCHEMBL3881836; BDBM50146477
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| Activity |
IC50 = 60000 nM
|
[24] | |||
| Compound Name |
5-[2-[4-(3-Chlorophenyl)phenyl]-2-oxoethyl]-5-hydroxy-1,3-diazinane-2,4,6-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2151353; BDBM50392684
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[32] | |||
| Compound Name |
N-[(Hydroxyamino)carbonyl]-L-leucyl-Lphenylalanine methylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL501715; BDBM50272134
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[33] | |||
| Compound Name |
N-Heptyl-N-hydroxycarbamoylmethyl-2-[1-pentyl-3-(4-phenoxy-phenyl)-ureido]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94873; BDBM50081797
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[13] | |||
| Compound Name |
N-Hydroxycarbamoylmethyl-2-[3-(4-phenoxy-phenyl)-1-(1,2,3,4-tetrahydro-naphthalen-1-yl)-ureido]-N-(1,2,3,4-tetrahydro-naphthalen-1-yl)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97408; BDBM50081796
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[13] | |||
| Compound Name |
Ethyl 5-carbamoyl-1H-indole-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ethyl 5-carbamoylindole-2-carboxylate; CHEMBL1939862; SCHEMBL6517054; BDBM50361620; ZINC45287075; AKOS032960944; 5-Cabamoyl-2-indole carboxylic acid ethyl ester; Q27455014
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[34] | |||
| Compound Name |
(2S)-2-Amino-N-[(3S)-1-[2-(3-chloroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1214543; BDBM50323938; (2S)-2-Amino-N-(1-(2-(3-chlorophenylamino)-2-oxoethyl)-2,6-dioxopiperidin-3-yl)-3-phenylpropanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 60400 nM
|
[35] | |||
| Compound Name |
2-[2-[(E)-(5-Oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]phenoxy]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927185; BDBM50359723
Click to Show/Hide
|
||||
| Activity |
IC50 = 61000 nM
|
[36] | |||
| Compound Name |
N-[4-[[4-[2-(2,5-Dimethylpyridin-4-yl)ethyl]piperidin-1-yl]sulfonylmethyl]oxan-4-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1784338; BDBM50345513
Click to Show/Hide
|
||||
| Activity |
IC50 = 61000 nM
|
[37] | |||
| Compound Name |
(2S)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-3-(4-hydroxyphenyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819325; BDBM50351026
Click to Show/Hide
|
||||
| Activity |
IC50 = 61300 nM
|
[22] | |||
| Compound Name |
(2S)-2-Amino-N-[(3S)-1-[2-(2-fluoroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1214544; BDBM50323939; (2S)-2-Amino-N-(1-(2-(2-fluorophenylamino)-2-oxoethyl)-2,6-dioxopiperidin-3-yl)-3-phenylpropanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 62700 nM
|
[35] | |||
| Compound Name |
4-Phenoxybutyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254610; BDBM50227602
Click to Show/Hide
|
||||
| Activity |
IC50 = 63000 nM
|
[26] | |||
| Compound Name |
Perfluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253820; BDBM50227562
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[26] | |||
| Compound Name |
Schembl22225166
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2048503
Click to Show/Hide
|
||||
| Activity |
IC50 = 64190 nM
|
[38] | |||
| Compound Name |
N-[(E)-(4-Dimethylaminophenyl)methyleneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775617; BDBM50155289
Click to Show/Hide
|
||||
| Activity |
IC50 = 64300 nM
|
[30] | |||
| Compound Name |
(S,E)-5-(2-Chlorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL476639; BDBM50267465
Click to Show/Hide
|
||||
| Activity |
IC50 = 64300 nM
|
[31] | |||
| Compound Name |
4-Bromo-N-hydroxybenzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
p-Bromo-N-hydroxybenzenesulfonamide; Benzenesulfonamide, p-bromo-N-hydroxy-; 4-bromo-N-hydroxybenzene-1-sulfonamide; N-(p-bromobenzenesulfonyl)hydroxylamine; BRN 2645335; Hydroxysulfonamide 56; p-Bromobenzenesulfonhydroxamide; CHEMBL123404; SCHEMBL8229526; BDBM11375; CTK8H4740; DTXSID90941675; N-Hydroxy-p-bromobenzenesulfonamide; ZINC6093148; 4-Bromo-N-hydroxybenzenesulfonamide #
Click to Show/Hide
|
||||
| Activity |
Ki = 65000 nM
|
[39] | |||
| Compound Name |
Thiophen-3-yl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL398838; BDBM50227596
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[26] | |||
| Compound Name |
Benzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399070; SCHEMBL20083642; BDBM50227551; benzyl 6-oxo-1H-pyridine-2-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[26] | |||
| Compound Name |
2,6-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253375; BDBM50227604
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[26] | |||
| Compound Name |
2,6-Difluorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL250058; BDBM50227531
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[26] | |||
| Compound Name |
Cyclobutyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251937; BDBM50227567
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[26] | |||
| Compound Name |
3-(4-(2-Oxo-2H-chromen-3-yl)-2-thioxo-2,3-dihydro-1H-imidazol-1-yl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927183; ZINC2957866; BDBM50359721; AKOS024602290; MCULE-4659831116; F0920-6501
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[36] | |||
| Compound Name |
Isopropyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL445939; BDBM50227603
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[26] | |||
| Compound Name |
N-[(E)-Benzylideneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775452; BDBM50155286
Click to Show/Hide
|
||||
| Activity |
IC50 = 67010 nM
|
[30] | |||
| Compound Name |
(2R)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819324; BDBM50351025
Click to Show/Hide
|
||||
| Activity |
IC50 = 67400 nM
|
[22] | |||
| Compound Name |
Methyl (2S)-2-benzamido-3-(4-phenylmethoxyphenyl)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2147932; BDBM50391633
Click to Show/Hide
|
||||
| Activity |
IC50 = 67500 nM
|
[40] | |||
| Compound Name |
3-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254240; BDBM50227564
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[26] | |||
| Compound Name |
Phenethyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL255051; BDBM50227541
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[26] | |||
| Compound Name |
2-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399685; BDBM50227554
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[26] | |||
| Compound Name |
4-Chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254238; BDBM50227571
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[26] | |||
| Compound Name |
3,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399684; BDBM50227534
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[26] | |||
| Compound Name |
N-Hydroxybenzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Benzenesulfohydroxamic acid; Piloty's acid; Benzenesulfonamide, N-hydroxy-; Benzenesulphonohydroxamic acid; Benzsulfohydroxamic acid; Hydroxamic acid, benzsulfo-; N-(Phenylsulfonyl)hydroxylamine; Hydroxylamine, N-(phenylsulfonyl)-; UNII-C64L4UMH19; CHEMBL55310; C64L4UMH19; MFCD00025013; EINECS 209-973-8; N-Hydroxy-benzenesulfonamide; BRN 2257368; Benzenesulfohyd; piloty acid; BENZENESULFOHYDROXAMICACID; Hydroxysulfonamide 53; Hydroxyphenylsulfonamide; Benzenesulfhydroxamic acid; (hydroxyamino)phenylsulfone; C6H7NSO3; Benzenesulfonamide,N-hydroxy-; 4-11-00-00093 (Beilstein Handbook Reference); SCHEMBL184252; DTXSID4060521; BDBM11372; CTK5B0780; HMS3650A13; NSC45357; ZINC4284435; 1634AH; 7672AF; ANW-43953; NSC-45357; AKOS001139035; MCULE-1579584179; NE34189; VZ36592; AS-59127; ST50825041; SR-01000946758; SR-01000946758-1; Q27275238
Click to Show/Hide
|
||||
| Activity |
Ki = 70000 nM
|
[39] | |||
| Compound Name |
4-Chloro-N-hydroxybenzene-1-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
N-(p-chlorobenzenesulfonyl)hydroxylamine; 4-chloro-N-hydroxybenzenesulfonamide; NSC528513; Hydroxysulfonamide 55; CHEMBL301469; SCHEMBL5194625; BDBM11374; DTXSID10326460; ZINC1607221; 4-Chloro-N-hydroxy-benzenesulfonamide; NSC-528513; DS-014970
Click to Show/Hide
|
||||
| Activity |
Ki = 70000 nM
|
[39] | |||
| Compound Name |
3-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL398892; BDBM50227585
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[26] | |||
| Compound Name |
1,10-Phenanthroline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
o-phenanthroline; Phenanthroline; orthophenanthroline; 4,5-diazaphenanthrene; 1,10-o-phenanthroline; 2-phenanthroline; 1,10-Phenanthroline anhydrous; [1,10]phenanthroline; beta-phenanthroline; 1,10-Fenanthrolin; .beta.-Phenanthroline; 1,10-Phenanthroline, Anhydrous; MFCD00011678; UNII-W4X6ZO7939; MLS000069797; CHEMBL415879; NSC 4265; W4X6ZO7939; NSC203545; NSC4265; SMR000058190; DSSTox_CID_5857; pyridino[3,2-h]quinoline; DSSTox_RID_77950; DSSTox_GSID_25857; 1,10-Phenanthroline, 99+%; MLS002701886; 1,10-Fenanthrolin [Czech]; Activ-8; NSC-4265; CCRIS 4855; EINECS 200-629-2; NSC 203545; phenantroline; o-Phenanthrolin; Cyto5A5; 1,10-phenanthrolin; 1,10-phenantroline; 1,10-phenathroline; 1,10 phenanthroline; 1,10-Fenanthroline; 1.10-phenanthroline; 1,1 0-phenanthroline; ACMC-209nwd; Opera_ID_711; [1,10]-Phenanthroline; Lopac-P-9375; Activ-8 in hexylene glycol; cid_1318; SCHEMBL8312; NCIStruc1_000192; NCIStruc2_000199; Lopac0_000985; KSC241K8T; ARONIS014409; DTXSID1025857; WLN: T B666 CN NNJ; 1,10 CPhenanthroline anhydrous; NCI4265; 1,10-Phenanthroline (anhydrous); 1,10-Phenanthroline, >=99%; 1,10-Phenanthroline,hydrochloride; HMS2234D03; HMS3263E11; HMS3371F11; ZINC164363; KS-000044UM; Tox21_201998; Tox21_303111; Tox21_500985; ANW-35243; BDBM50092158; CCG-38059; NCGC00013043; s6830; SBB089685; STL069281; AKOS000281773; CS-W004544; DB02365; HY-W004544; LP00985; MCULE-2911225521; NSC-203545; SDCCGSBI-0050958.P003; NCGC00013043-02; NCGC00013043-03; NCGC00013043-04; NCGC00013043-05; NCGC00013043-06; NCGC00013043-07; NCGC00013043-08; NCGC00013043-09; NCGC00013043-10; NCGC00013043-13; NCGC00091201-01; NCGC00091201-02; NCGC00091201-03; NCGC00091201-04; NCGC00257123-01; NCGC00259547-01; NCGC00261670-01; AC-18353; AK-27000; AS-14043; BR-27000; NCI60_003976; SC-23392; DB-013750; EU-0100985; FT-0606035; FT-0660636; P0221; P0879; P1826; ST45051101; Solution forms containing 1,10-phenanthroline; C-1044; C00604; M-5271; P 9375; 011P678; A835532; AA-860/25004133; Q416005; SR-01000076093; CU-00000000156-1; J-610043; SR-01000076093-1; W-104740; F3377-1129
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[41] | |||
| Compound Name |
But-2-ynyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254837; BDBM50227600
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[26] | |||
| Compound Name |
2,5-Difluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399304; BDBM50227547
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[26] | |||
| Compound Name |
3-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252965; BDBM50227578
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[26] | |||
| Compound Name |
Methyl (E)-5-(4-hydroxyphenyl)-2-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-3-oxopent-4-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL2124084; CHEMBL3922961; US9187406, Compound 3; BDBM191767
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[41] | |||
| Compound Name |
4-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253374; BDBM50227557
Click to Show/Hide
|
||||
| Activity |
IC50 = 71000 nM
|
[26] | |||
| Compound Name |
2-Fluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253373; BDBM50227552
Click to Show/Hide
|
||||
| Activity |
IC50 = 71000 nM
|
[26] | |||
| Compound Name |
{(R)-3-[(S)-2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylcarbamoyl]-5-methyl-hexanoylaminooxy}-acetic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL308032; BDBM50062320
Click to Show/Hide
|
||||
| Activity |
Ki = 71000 nM
|
[42] | |||
| Compound Name |
(S,E)-5-(4-Bromophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL514357; BDBM50267370
Click to Show/Hide
|
||||
| Activity |
IC50 = 71200 nM
|
[31] | |||
| Compound Name |
(R)-4-(4-Carboxy-2-(3,4,5-trimethoxybenzamido)butanamido)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL489026; BDBM50267958
Click to Show/Hide
|
||||
| Activity |
IC50 = 71200 nM
|
[21] | |||
| Compound Name |
(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(2-fluorophenylamino)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL476638; BDBM50267464
Click to Show/Hide
|
||||
| Activity |
IC50 = 71400 nM
|
[31] | |||
| Compound Name |
(2S)-2-Amino-N-[(3S)-1-[2-(4-bromoanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1214590; BDBM50323940; (2S)-2-Amino-N-(1-(2-(4-bromophenylamino)-2-oxoethyl)-2,6-dioxopiperidin-3-yl)-3-phenylpropanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 71600 nM
|
[35] | |||
| Compound Name |
2-[1-Sec-Butyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-N-isopropyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL95004; BDBM50081786
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[13] | |||
| Compound Name |
N-(p-Fluorobenzenesulfonyl)hydroxylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-fluoro-N-hydroxybenzene-1-sulfonamide; Hydroxysulfonamide 54; CHEMBL332145; SCHEMBL2492594; BDBM11373; 4-fluoro-n-hydroxybenzenesulfonamide; N-Hydroxy-4-fluorobenzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
Ki = 72000 nM
|
[39] | |||
| Compound Name |
3-Methylbut-2-enyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254627; BDBM50227565
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[26] | |||
| Compound Name |
(Hydroxyamino)(4-iodophenyl)sulfone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Hydroxysulfonamide 57; CHEMBL120934; SCHEMBL8229583; BDBM11376; ZINC5570003; AKOS024355469; N-hydroxy-4-iodobenzene-1-sulfonamide; MCULE-2099459518; ST50982751
Click to Show/Hide
|
||||
| Activity |
Ki = 72000 nM
|
[39] | |||
| Compound Name |
Benzenemethanesulfonamide, N-hydroxy-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Hydroxysulfonamide 52; N-Benzylsulfonylhydroxylamin; CHEMBL333122; N-hydroxyphenylmethanesulfonamide; SCHEMBL10656290; BDBM11371; N-hydroxy-1-phenylmethanesulfonamide
Click to Show/Hide
|
||||
| Activity |
Ki = 73000 nM
|
[39] | |||
| Compound Name |
Thiophen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254039; BDBM50227537
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[26] | |||
| Compound Name |
6-Oxo-1,6-dihydro-pyridine-2-carboxylic acid 4-methyl-benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253801; BDBM50227586
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[26] | |||
| Compound Name |
Cyclohexyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL442286; BDBM50227588
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[26] | |||
| Compound Name |
Methyl (2S)-2-benzamido-3-[4-(2-phenylethoxy)phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2147937; BDBM50391639
Click to Show/Hide
|
||||
| Activity |
IC50 = 74600 nM
|
[40] | |||
| Compound Name |
(R)-6-Cyclohexyl-N-hydroxy-3-(3-(piperidine-1-carbonyl)-1,2,4-oxadiazol-5-yl)hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL480351; BDBM50256305
Click to Show/Hide
|
||||
| Activity |
IC50 = 74900 nM
|
[5] | |||
| Compound Name |
N-[(E)-(2,4-Dimethoxyphenyl)methylideneamino]-2-(3-methyl-2-oxoquinoxalin-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3774826; BDBM50155293; N-[(E)-(2,4-dimethoxyphenyl)methyleneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 74910 nM
|
[30] | |||
| Compound Name |
3-Hydroxy-4H-pyran-4-thione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1649594; 4H-Pyran-4-thione, 3-hydroxy-; 3-hydroxypyran-4-thione; Thiomeconic acid; ACMC-20lkcd; SCHEMBL1298196; CTK2J8099; DTXSID10463243; BDBM50335806
Click to Show/Hide
|
||||
| Activity |
IC50 = 76000 nM
|
[10] | |||
| Compound Name |
N-[1-[4-(4-Cyanophenyl)phenoxy]propan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41067; SCHEMBL7453489; BDBM50100919; N-[1-Methyl-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid; N-[2-(4''-Cyano-biphenyl-4-yloxy)-1-methyl-ethyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 76000 nM
|
[27] | |||
| Compound Name |
(R)-5-(4-Bromo-2-fluorobenzylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL476657; BDBM50267360
Click to Show/Hide
|
||||
| Activity |
IC50 = 76100 nM
|
[21] | |||
| Compound Name |
(4S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(3-(4-fluorophenyl)-1-methoxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523446; BDBM50267608
Click to Show/Hide
|
||||
| Activity |
IC50 = 76500 nM
|
[31] | |||
| Compound Name |
(R)-5-(3-Iodobenzylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL477449; BDBM50267319
Click to Show/Hide
|
||||
| Activity |
IC50 = 76800 nM
|
[21] | |||
| Compound Name |
(4S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(1-methoxy-3-methyl-1-oxobutan-2-ylamino)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL491656; BDBM50267568
Click to Show/Hide
|
||||
| Activity |
IC50 = 76800 nM
|
[31] | |||
| Compound Name |
N-Hydroxy-4-methylbenzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Benzenesulfonamide, N-hydroxy-4-methyl-; N-hydroxy-4-methylbenzene-1-sulfonamide; tosylhydroxylamine; N-Tosylhydroxylamine; N-hydroxy-4-methyl-benzenesulfonamide; Hydroxysulfonamide 58; ACMC-209djs; p-tolyl-N-hydroxysulfonamide; N-hydroxy-4-toluenesulfonamide; CHEMBL121559; SCHEMBL1832454; BDBM11377; CTK8B0907; DTXSID10435263; ANW-21830; MFCD11850835; ZINC13813791; AKOS015888649; MCULE-3823003338; SC-50302; DB-064280; CS-0068832; FT-0760726; V3581; A-3307
Click to Show/Hide
|
||||
| Activity |
Ki = 77000 nM
|
[39] | |||
| Compound Name |
Thiophen-3-yl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399999; BDBM50227561
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[26] | |||
| Compound Name |
Methyl (8S)-7-(4-nitrophenyl)sulfonyl-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3092085; BDBM50494836
Click to Show/Hide
|
||||
| Activity |
IC50 = 77930 nM
|
[43] | |||
| Compound Name |
2-Amino-5-(4-((thiiran-2-ylmethyl)sulfonyl)phenoxy)phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834423; SCHEMBL2369869; BDBM50354625; 2-amino-5-[4-(thiiran-2-ylmethylsulfonyl)phenoxy]phenol
Click to Show/Hide
|
||||
| Activity |
Ki = 78000 nM
|
[44] | |||
| Compound Name |
(2S)-2-Amino-3-thiol-N-[(2R)-2-amino-3-phenylpropyl]propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457867; BDBM50273669
Click to Show/Hide
|
||||
| Activity |
IC50 = 78800 nM
|
[45] | |||
| Compound Name |
2,5-Difluorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400449; BDBM50227576
Click to Show/Hide
|
||||
| Activity |
IC50 = 79000 nM
|
[26] | |||
| Compound Name |
(3R)-6-Cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1,2,4-oxadiazol-5-yl]-N-hydroxyhexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL226852; SCHEMBL6599390; BDBM50216790
Click to Show/Hide
|
||||
| Activity |
IC50 = 79600 nM
|
[46] | |||
| Compound Name |
(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(2-methoxy-2-oxoethylamino)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL489414; BDBM50267566
Click to Show/Hide
|
||||
| Activity |
IC50 = 79600 nM
|
[31] | |||
| Compound Name |
(R)-Ethyl 5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL374840; SCHEMBL6430169; BDBM50216798; ethyl 5-[(3R)-6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl]-1,2,4-oxadiazole-3-carboxylate; Ethyl 5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-1,2,4-oxadiazole-3-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[5] | |||
| Compound Name |
N-[(E)-(4-Chlorophenyl)methyleneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3774656; BDBM50155290
Click to Show/Hide
|
||||
| Activity |
IC50 = 81010 nM
|
[30] | |||
| Compound Name |
Chembl4211480
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50457772
Click to Show/Hide
|
||||
| Activity |
IC50 = 81210 nM
|
[23] | |||
| Compound Name |
(R)-N-Benzyl-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N-methyl-1,2,4-oxadiazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL482319; BDBM50256366
Click to Show/Hide
|
||||
| Activity |
IC50 = 81800 nM
|
[5] | |||
| Compound Name |
Ethyl 5-(5-methoxycarbonyl-2-methylpyrazol-3-yl)-1H-indole-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939873; BDBM50361631
Click to Show/Hide
|
||||
| Activity |
IC50 = 83000 nM
|
[34] | |||
| Compound Name |
(4S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(1-methoxy-1-oxopropan-2-ylamino)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL489415; BDBM50267567
Click to Show/Hide
|
||||
| Activity |
IC50 = 83200 nM
|
[31] | |||
| Compound Name |
Methyl (2S)-2-[(4-methylbenzoyl)amino]-3-(4-phenylmethoxyphenyl)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2147933; BDBM50391616
Click to Show/Hide
|
||||
| Activity |
IC50 = 83700 nM
|
[40] | |||
| Compound Name |
(2S)-N-[(2S,3S)-2-Amino-3-hydroxy-3-(4-nitrophenyl)propyl]-2-[[(2S)-3-amino-2-hydroxypropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819327; BDBM50351028
Click to Show/Hide
|
||||
| Activity |
IC50 = 83900 nM
|
[22] | |||
| Compound Name |
(2S)-2,6-Diamino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819323; BDBM50351024
Click to Show/Hide
|
||||
| Activity |
IC50 = 84300 nM
|
[22] | |||
| Compound Name |
Hexyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249859; BDBM50227581
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[26] | |||
| Compound Name |
US9187406, Curcumin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3892642; SCHEMBL10077702; BDBM191763
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[41] | |||
| Compound Name |
Benzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL402720; BDBM50227533
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[26] | |||
| Compound Name |
(E)-5-(4-Hydroxy-3-methoxyphenyl)-2-[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]-3-oxo-N-phenylpent-4-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL2124629; CHEMBL3962579; US9187406, Compound 6; BDBM191769
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[41] | |||
| Compound Name |
3-(Hydroxymethyl)-6-(4-hydroxyphenyl)-2-[2-(4-hydroxyphenyl)ethynyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3585679; BDBM50093523
Click to Show/Hide
|
||||
| Activity |
IC50 = 85350 nM
|
[23] | |||
| Compound Name |
Methyl (2S)-2-[(4-methylbenzoyl)amino]-3-[4-(2-phenylethoxy)phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2147938; BDBM50391638
Click to Show/Hide
|
||||
| Activity |
IC50 = 85500 nM
|
[40] | |||
| Compound Name |
2,4,5-Trifluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL398450; BDBM50227548
Click to Show/Hide
|
||||
| Activity |
IC50 = 86000 nM
|
[26] | |||
| Compound Name |
(R)-4-(4-Carboxy-2-(3,4,5-trimethoxybenzamido)butanamido)-2-hydroxybenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL489231; BDBM50267959
Click to Show/Hide
|
||||
| Activity |
IC50 = 86300 nM
|
[21] | |||
| Compound Name |
(2S)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-iodophenyl)propyl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819448; BDBM50351044
Click to Show/Hide
|
||||
| Activity |
IC50 = 86600 nM
|
[22] | |||
| Compound Name |
(4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL362099; BDBM50152637
Click to Show/Hide
|
||||
| Activity |
Ki = 88000 nM
|
[47] | |||
| Compound Name |
Epicatechin 3-O-(3-O-methylgallate)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL158521; (-)-ECG-3''-O-ME; (-)-Epicatechin-3-(3''-O-methyl) gallate; CTK6J6178; 3-O-(3-Methylgalloyl)epicatechin; Epicatechin 3-(3-O-methylgallate); BDBM50296236; epicatechin 3-(3'-O-methylgallate); LMPK12020093; ZINC14642643; epicatechin 3-O-(3'-O-methylgallate); (-)-epicatechin 3-(3'-O-methylgallate); (-)-epicatechin 3-O-(3'-O-methylgallate)
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[48] | |||
| Compound Name |
3-Methoxybenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254406; BDBM50227568
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[26] | |||
| Compound Name |
4-Phenoxybutyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253372; BDBM50227559
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[26] | |||
| Compound Name |
Cinnamyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254657; BDBM50227587
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[26] | |||
| Compound Name |
2-[1-[2-(4-Fluoro-phenyl)-ethyl]-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-N-isopropyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL95143; BDBM50081793
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[13] | |||
| Compound Name |
2,4,5-Trifluorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL250059; BDBM50227592
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[26] | |||
| Compound Name |
2-(3-Methyl-2-oxoquinoxalin-1-yl)-N-[(E)-1-(4-nitrophenyl)ethylideneamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775356; BDBM50155282; 2-(3-methyl-2-oxo-quinoxalin-1-yl)-N-[(E)-1-(4-nitrophenyl)ethylideneamino]acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 90810 nM
|
[30] | |||
| Compound Name |
4-Methoxybenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399908; BDBM50227579
Click to Show/Hide
|
||||
| Activity |
IC50 = 91000 nM
|
[26] | |||
| Compound Name |
(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL439012; SCHEMBL6178395; BDBM50216817
Click to Show/Hide
|
||||
| Activity |
IC50 = 92000 nM
|
[46] | |||
| Compound Name |
4-Phenoxybenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL250070; BDBM50227532
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[26] | |||
| Compound Name |
(2S)-N-[(2S,3S)-2-Amino-3-(4-aminophenyl)-3-hydroxypropyl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819445; BDBM50351041
Click to Show/Hide
|
||||
| Activity |
IC50 = 94000 nM
|
[22] | |||
| Compound Name |
4-Chlorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251081; BDBM50227556
Click to Show/Hide
|
||||
| Activity |
IC50 = 96000 nM
|
[26] | |||
| Compound Name |
Naphthalen-1-yl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251423; BDBM50227543
Click to Show/Hide
|
||||
| Activity |
IC50 = 98000 nM
|
[26] | |||
| Compound Name |
6-Mercapto-pyridine-2-carboxylic acid 4-methyl-benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254404; BDBM50227582
Click to Show/Hide
|
||||
| Activity |
IC50 = 98000 nM
|
[26] | |||
| Compound Name |
3-Methyl-2-oxo-quinoxaline-1(2h)-acetohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775799; BDBM50155274; AKOS012886366; 2-(3-methyl-2-oxo-quinoxalin-1-yl)acetohydrazide
Click to Show/Hide
|
||||
| Activity |
IC50 = 98020 nM
|
[30] | |||
| Compound Name |
6-Amino-N-[(2R)-2-amino-3-phenylpropyl]caproylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL448755; BDBM50273671
Click to Show/Hide
|
||||
| Activity |
IC50 = 99700 nM
|
[45] | |||
| Compound Name |
(2S)-2,6-Amino-N-[(2R)-2-amino-3-phenylpropyl]caproylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457648; BDBM50273633
Click to Show/Hide
|
||||
| Activity |
IC50 = 99700 nM
|
[45] | |||
| Compound Name |
6-[5-(5,7-Dihydroxy-4-oxo-chromen-2-yl)-2-methoxy-phenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL451902; robustaflavone-4'-methyl ether; Robustaflavone-4''''-Methyl Ether; BDBM50457775; 4''',5,5'',7,7''-Pentahydroxy-4'-methoxy-3',6''-biflavone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
N-[(2S)-1-(Dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL84969; BB-3554; SCHEMBL4956500; BDBM50104500; 2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((S)-1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)aminobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3585760; SCHEMBL13570529; BDBM50093566; (2S)-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]butanoic acid; (S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)-aminobutanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[50] | |||
| Compound Name |
(R)-2-(5-(6-Cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-1,2,4-oxadiazole-3-carboxamido)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL480191; SCHEMBL6430699; BDBM50256303
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
Chembl4213048
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50457778
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
(P-Tolylamino)methylenediphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2440439; SCHEMBL11570312; BDBM50442518; ZINC96286211; p-tolylaminomethylenedi-phosphonic acid; (4-Methylphenyl)aminomethylenebisphosphonic acid; [(4-methylanilino)-phosphonomethyl]phosphonic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(3R)-6-Cyclohexyl-N-hydroxy-3-{3-[1-(methylsulfonyl)-4-piperidinyl]-1,2,4-oxadiazol-5-yl}hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL226840; BDBM50216838
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
(2R)-4-Fluoro-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3585763; SCHEMBL13570653; BDBM50093569; (R)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)-2-amino-4-fluorobutanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[50] | |||
| Compound Name |
[(4-Phenylanilino)-phosphono-methyl]phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL293479; BDBM50138035; NSC725580; ZINC13673810; NSC-725580; (biphenyl-4-ylamino)methylenediphosphonic acid; (biphenyl-4-yl)-aminomethylene-1,1-bisphosphonate; (Biphenyl-4-yl)- aminomethylene-1,1-bisphosphonate; [(Biphenyl-4-ylamino)-phosphono-methyl]-phosphonic acid; Phosphonic acid, [([1,1'-biphenyl]-4-ylamino)methylene]bis-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
[(2,4-Dichloroanilino)-phosphono-methyl]phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL191613; BDBM50165966; 2,4-Dichloroanilinomethylenebisphosphonic acid; 2,4-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID; [(2,4-dichloro-phenyl)aminomethylene]-1,1-bisphosphonate; [(2,4-Dichloro-phenylamino)-phosphono-methyl]-phosphonic acid; Phosphonic acid, [[(2,4-dichlorophenyl)amino]methylene]bis-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
(5S)-4-[2-(1-Adamantyl)ethyl]-5-butyl-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3593549; BDBM50104623
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[51] | |||
| Compound Name |
CID 50943150
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933882; BDBM50360393; (E)-2-(1H-benzimidazol-2-yl)-3-(5-thiophen-2-ylthiophen-2-yl)prop-2-enenitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
2-(Benzyl-hydroxycarbamoylmethyl-amino)-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL234737; BDBM50241254; N-Benzyl-N-{[2-(4-sulfamoylphenyl)ethylcarbamoyl]methyl}-aminoacetohydroxamic Acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)-aminopent-4-enoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3585768; SCHEMBL13570710; BDBM50093574; (2S)-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]pent-4-enoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[50] | |||
| Compound Name |
(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3394285; SCHEMBL12425758; BDBM50140176; (E)-3-[4-(trifluoromethyl)phenyl]prop-2-enehydroxamic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[54] | |||
| Compound Name |
Schembl21751149
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3235912; BDBM50104619
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[51] | |||
| Compound Name |
[(4S,5S)-2-(4-Nitro-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl]-methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL364775; BDBM50152643
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[47] | |||
| Compound Name |
[Pentyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328477; BDBM50081775; N-Hydroxycarbamoylmethyl-N-pentyl-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[13] | |||
| Compound Name |
(R)-5-(6-Cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N-isopropyl-1,2,4-oxadiazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL480757; SCHEMBL6429362; BDBM50256203; 5-[(3R)-6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl]-N-propan-2-yl-1,2,4-oxadiazole-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(2S,3S,4R)-4-(4,5-Dihydroxy-3-methoxy-6-methyloxan-2-yl)oxy-8,10-bis(dimethylamino)-2,5,7-trihydroxy-3-methoxy-2-methyl-3,4-dihydrotetracene-1,6,11-trione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328472; BDBM50001008
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[55] | |||
| Compound Name |
(5S)-5-Benzyl-1-[(2R)-1-[(2S)-2-[[(6R)-6-benzyl-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-cyclohexylpropan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3593552; BDBM50104618
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[51] | |||
| Compound Name |
(Hydroxysulfamoyl)dimethylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Hydroxysulfonamide 51; CHEMBL330950; SCHEMBL6791061; BDBM11370; N-(Dimethylsulfamoyl)hydroxylamine
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[39] | |||
| Compound Name |
[Anilino(phosphono)methyl]phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2440580; SCHEMBL7796889; N-phenylaminomethanediphosphonic acid; BDBM50442523; Phenylaminomethylenebisphosphonic acid; (PHENYLAMINO)METHYLENEDIPHOSPHONIC ACID
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
5-{(1R)-4-Cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-N,N-dimethyl-1,2,4-oxadiazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL226686; SCHEMBL6428452; BDBM50241177; (R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N,N-dimethyl-1,2,4-oxadiazole-3-carboxamide; 5-[(3R)-6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl]-N,N-dimethyl-1,2,4-oxadiazole-3-carboxamide; 5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoethyl]butyl}-1,2,4-oxadiazole-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[2-Methyl-1-[[4-(5-methylthiophen-2-yl)phenyl]sulfonylamino]propyl]phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752826; BDBM50500715
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
Acetic acid 3-acetoxy-5-methoxy-2-methyl-6-(3,10,12-trihydroxy-2-methoxy-3-methyl-4,6,11-trioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-tetrahydro-pyran-4-yl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91905; BDBM50001016
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[55] | |||
| Compound Name |
(S)-N-(4-Methoxyphenylsulfonyl)-N-(3-pyridylmethyl)-2-amino-4-fluoropent-4-enoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3585772; SCHEMBL13570522; BDBM50093578; (2S)-4-fluoro-2-[(4-methoxyphenyl)sulfonyl-(pyridin-3-ylmethyl)amino]pent-4-enoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[50] | |||
| Compound Name |
Cyclohexanamine;2-methylpropylcarbamoylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1160685
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
(2R)-N-Hydroxy-2-[[1-[2-[2-[2-[2-[4-[[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-methoxyphenyl)sulfonylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl-(4-methoxyphenyl)sulfonylamino]-3-methylbutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2064553; BDBM50389105
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[57] | |||
| Compound Name |
1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-3-hydroxyurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41928; BDBM50100898; N-{2-[(4''-cyano-1,1''-biphenyl-4-yl)oxy]ethyl}-N''-hydroxyurea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[27] | |||
| Compound Name |
Naphthalen-2-yl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251424; BDBM50227584
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[26] | |||
| Compound Name |
1,1,1-Trifluoro-N-hydroxymethanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Hydroxysulfonamide 47; CHEMBL331308; SCHEMBL8231627; BDBM11366; CTK1H6610; DTXSID10635307; Methanesulfonamide, 1,1,1-trifluoro-N-hydroxy-
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[39] | |||
| Compound Name |
CID 78426619
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3235911; SCHEMBL20271444; BDBM50104621
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[51] | |||
| Compound Name |
Thioacetic acid S-[(4S,5S)-2-((E)-styryl)-5-vinyl-4,5-dihydro-oxazol-4-yl] ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL364212; BDBM50152631
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[47] | |||
| Compound Name |
(5S)-5-Benzyl-1-[(2R)-1-cyclohexyl-3-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3593551; BDBM50104620
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[51] | |||
| Compound Name |
(2E)-2-(1H-Benzimidazol-2-yl)-3-(3-iodo-4-methoxyphenyl)prop-2-enenitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1933865; BDBM50360392; STK288035; ZINC13943922; AKOS000417983; NCGC00330396-01; AB01325241-02
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
4-Chloroanilinomethylenebisphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2440579; BDBM50442521; ZINC59245747; N-(p-chlorphenyl)-aminomethanediphosphonic acid; (4-CHLOROPHENYLAMINO)METHYLENEDIPHOSPHONIC ACID
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
3,4-Dichloroanilinomethylenebisphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2440433; BDBM50442512; ZINC96286205; 3,4-DICHLOROPHENYLAMINOMETHYLENEBISPHOSPHONIC ACID
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL318252; SCHEMBL3882021; BDBM50146472
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
trans-2-Aminocyclohexylcarbamoylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL270296; SCHEMBL4854279; BDBM50372742; ZINC29134636; [(1R,2R)-2-aminocyclohexyl]carbamoylphosphonic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
[1-[[4-[5-(Methoxymethyl)thiophen-2-yl]phenyl]sulfonylamino]-2-methylpropyl]phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3754314; BDBM50500719
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
N-Methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400314; BDBM50241371; 1-(2-(methylamino)-2-oxoethyl)-3-(5-thioxo-4,5-dihydro-1,3,4-thiadiazol-2-yl)urea; N-Methyl-2-[3-[(5-thioxo-4,5-dihydro-1,3,4-thiadiazole)-2-yl]ureido]acetamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[59] | |||
| Compound Name |
(3R)-6-Cyclohexyl-N-hydroxy-3-[3-(3-pyridinylmethyl)-1,2,4-oxadiazol-5-yl]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL437488; SCHEMBL6429290; BDBM50216848; (3R)-6-cyclohexyl-N-hydroxy-3-[3-(pyridin-3-ylmethyl)-1,2,4-oxadiazol-5-yl]hexanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
Chembl4206956
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50457774
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
Morpholin-4-ylcarbonylphosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97838; BDBM50146803
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PD-503; CHEMBL409536; SCHEMBL5957461; PD503; BDBM50234334; ZINC29133346; DB08561; Q27097766
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
Hydroxysulfonamide 48
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL124237; BDBM11367; 1,1,1-trichloro-N-hydroxymethanesulfonamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[39] | |||
| Compound Name |
N-Hydroxycarbamoylmethyl-N-(1-methyl-butyl)-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94887; BDBM50081771; N-Hydroxy-2-[(1-methylbutyl)[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[13] | |||
| Compound Name |
Ubenimex
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Bestatin; Ubenimex (Bestatin); UNII-I0J33N5627; MFCD00083262; NK-421; CHEMBL29292; 58970-76-6 (free base); I0J33N5627; Ubenimexum [Latin]; Ubenimexum; Ubenimex [INN:JAN]; Ubenimex(Bestatin); SMR000059165; EINECS 261-529-2; NK 421; NSC 265489; BRN 4704312; Ubestatin; Ubenimex, solid; NSC-265489; Ubenimex, Bestatin; Ubenimex,(S); SCHEMBL7944; (3-Amino-2-hydroxy-4-phenylbutanoyl)-L-leucine; Lopac0_000214; BSPBio_001553; KBioGR_000273; KBioSS_000273; MLS000028649; MLS001424177; MLS006010137; BCBcMAP01_000178; BDBM23971; KBio2_000273; KBio2_002841; KBio2_005409; KBio3_000545; KBio3_000546; Bio2_000273; Bio2_000753; HMS1361N15; HMS1791N15; HMS1989N15; HMS2052A03; HMS2232H13; HMS3268O06; HMS3402N15; HMS3412N16; HMS3676N16; HMS3715B20; EX-A1292; HY-B0134; KS-00000JJ0; ZINC1542895; BDBM50367209; KM0266; s1591; AKOS016339610; CCG-101071; CS-1910; DB03424; KS-5207; NC00321; QC-8204; SDCCGSBI-0050202.P003; IDI1_034023; SMP1_000030; NCGC00025323-01; NCGC00025323-02; NCGC00025323-03; NCGC00025323-04; NCGC00025323-05; NCGC00025323-06; NCGC00025323-08; NCGC00025323-14; AT-11558; BCP0726000308; AB0010690; ST50405897; AB00698345_05; 970B766; SR-01000075724-3; W-105351; BRD-K59574735-001-02-7; BRD-K59574735-001-05-0; Q10909912
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[61] | |||
| Compound Name |
(R)-2-(4-Fluorophenylsulphonamido-N-(pyridin-3-ylmethyl))-3-methylbutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL393793; BDBM50225398
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
(3R)-6-Cyclohexyl-N-hydroxy-3-(3-{[(methylsulfonyl)amino]-methyl}-1,2,4-oxadiazol-5-yl)hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL389020; SCHEMBL5411951; BDBM50216802; (R)-6-cyclohexyl-N-hydroxy-3-(3-(methylsulfonamidomethyl)-1,2,4-oxadiazol-5-yl)hexanamide; (3R)-6-cyclohexyl-N-hydroxy-3-[3-(methanesulfonamidomethyl)-1,2,4-oxadiazol-5-yl]hexanamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[7] | |||
| Compound Name |
3-Phenylpropyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252523; BDBM50227542
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[26] | |||
| Compound Name |
(2S)-3-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-2-hydroxypropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819321; BDBM50351022
Click to Show/Hide
|
||||
| Activity |
IC50 = 100100 nM
|
[22] | |||
| Compound Name |
N-[(2R)-2-Amino-3-phenylpropyl]-3,5-dinitrobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457448; BDBM50273774
Click to Show/Hide
|
||||
| Activity |
IC50 = 100700 nM
|
[45] | |||
| Compound Name |
Cyclohexyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254838; BDBM50227583
Click to Show/Hide
|
||||
| Activity |
IC50 = 101000 nM
|
[26] | |||
| Compound Name |
(4S,E)-5-(1,4-Dimethoxy-1,4-dioxobutan-2-ylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL521626; BDBM50267569
Click to Show/Hide
|
||||
| Activity |
IC50 = 101500 nM
|
[31] | |||
| Compound Name |
Pentyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252326; BDBM50227593
Click to Show/Hide
|
||||
| Activity |
IC50 = 103000 nM
|
[26] | |||
| Compound Name |
(S)-N,N-Diethyl-2-(2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamido)-3-phenyl-propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL599733; BDBM50306925
Click to Show/Hide
|
||||
| Activity |
IC50 = 105300 nM
|
[25] | |||
| Compound Name |
(2S)-N-[(2S,3S)-2-Amino-3-hydroxy-3-(4-nitrophenyl)propyl]-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819332; BDBM50351033
Click to Show/Hide
|
||||
| Activity |
IC50 = 105600 nM
|
[22] | |||
| Compound Name |
(2S)-N-Butyl-2-[[2-(3-methyl-2-oxoquinoxalin-1-yl)acetyl]amino]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL598119; BDBM50306924; (S)-N-Butyl-2-(2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamido)-3-phenylpropan-amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 106000 nM
|
[25] | |||
| Compound Name |
2-(2-(3-((S)-2-Amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1213732; BDBM50323950
Click to Show/Hide
|
||||
| Activity |
IC50 = 107000 nM
|
[35] | |||
| Compound Name |
Benzo[d][1,3]dioxol-5-ylmethyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253189; BDBM50227540
Click to Show/Hide
|
||||
| Activity |
IC50 = 107000 nM
|
[26] | |||
| Compound Name |
4-Bromobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254448; BDBM50227563
Click to Show/Hide
|
||||
| Activity |
IC50 = 107000 nM
|
[26] | |||
| Compound Name |
(2R)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-iodophenyl)propyl]amino]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819449; BDBM50351045
Click to Show/Hide
|
||||
| Activity |
IC50 = 107100 nM
|
[22] | |||
| Compound Name |
(R)-5-(3-Chloro-4-fluorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL477656; BDBM50267317
Click to Show/Hide
|
||||
| Activity |
IC50 = 107200 nM
|
[21] | |||
| Compound Name |
2-Bromobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399997; BDBM50227598
Click to Show/Hide
|
||||
| Activity |
IC50 = 108000 nM
|
[26] | |||
| Compound Name |
4-Fluorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL250057; BDBM50227527
Click to Show/Hide
|
||||
| Activity |
IC50 = 108000 nM
|
[26] | |||
| Compound Name |
(R)-5-(2,4-Difluorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL489232; BDBM50267960
Click to Show/Hide
|
||||
| Activity |
IC50 = 108700 nM
|
[21] | |||
| Compound Name |
(2R)-2-Amino-N-[(2S)-3-[[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]amino]-2-hydroxy-3-oxopropyl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819330; BDBM50351031
Click to Show/Hide
|
||||
| Activity |
IC50 = 108900 nM
|
[22] | |||
| Compound Name |
Naphthalen-1-yl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399504; BDBM50227555
Click to Show/Hide
|
||||
| Activity |
IC50 = 109000 nM
|
[26] | |||
| Compound Name |
2-(1-Benzyl-3-naphthalen-1-yl-ureido)-N-sec-butyl-N-hydroxycarbamoylmethyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL95187; BDBM50081782
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[13] | |||
| Compound Name |
4-Methoxybenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253172; BDBM50227538
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[26] | |||
| Compound Name |
6-Mercapto-pyridine-2-carboxylic acid biphenyl-4-ylmethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251425; BDBM50227590
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[26] | |||
| Compound Name |
N-[4-[4-(Thiiran-2-ylmethylsulfonyl)phenoxy]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL485492; N-(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl)acetamide; SCHEMBL314064; BDBM50264811
Click to Show/Hide
|
||||
| Activity |
Ki = 110000 nM
|
[44] | |||
| Compound Name |
3-(Trifluoromethyl)benzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254405; BDBM50227535
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[26] | |||
| Compound Name |
(2R)-2-Amino-N-[(2S)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]amino]-3-hydroxy-1-oxopropan-2-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819329; BDBM50351030
Click to Show/Hide
|
||||
| Activity |
IC50 = 110100 nM
|
[22] | |||
| Compound Name |
Furan-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254821; BDBM50227529
Click to Show/Hide
|
||||
| Activity |
IC50 = 111000 nM
|
[26] | |||
| Compound Name |
(2S)-2-Amino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]-3-(4-hydroxyphenyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819442; BDBM50351038
Click to Show/Hide
|
||||
| Activity |
IC50 = 111300 nM
|
[22] | |||
| Compound Name |
[4-(Trifluoromethyl)phenyl]methyl 6-oxo-1H-pyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1162966; BDBM50371234
Click to Show/Hide
|
||||
| Activity |
IC50 = 112000 nM
|
[26] | |||
| Compound Name |
(2S)-2-Amino-4-methylthio-N-[(2R)-2-amino-3-phenylpropyl]butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457649; BDBM50273634
Click to Show/Hide
|
||||
| Activity |
IC50 = 112100 nM
|
[45] | |||
| Compound Name |
N-[(E)-1-(2-Chlorophenyl)ethylideneamino]-2-(3-methyl-2-oxoquinoxalin-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775412; BDBM50155283; N-[(E)-1-(2-chlorophenyl)ethylideneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 112260 nM
|
[30] | |||
| Compound Name |
N-[2-(4-Fluoro-phenyl)-ethyl]-2-[1-heptyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL320908; BDBM50081792
Click to Show/Hide
|
||||
| Activity |
IC50 = 114000 nM
|
[13] | |||
| Compound Name |
(R)-5-(2-Nicotinoylhydrazinyl)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL521950; BDBM50267881
Click to Show/Hide
|
||||
| Activity |
IC50 = 114900 nM
|
[21] | |||
| Compound Name |
(S,E)-5-(3,5-Difluorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL476637; BDBM50267463
Click to Show/Hide
|
||||
| Activity |
IC50 = 116300 nM
|
[31] | |||
| Compound Name |
Phenethyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252522; BDBM50227599
Click to Show/Hide
|
||||
| Activity |
IC50 = 119000 nM
|
[26] | |||
| Compound Name |
(2S)-2-Amino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819334; BDBM50351035
Click to Show/Hide
|
||||
| Activity |
IC50 = 119300 nM
|
[22] | |||
| Compound Name |
(2S)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-iodophenyl)propyl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819446; BDBM50351042
Click to Show/Hide
|
||||
| Activity |
IC50 = 119500 nM
|
[22] | |||
| Compound Name |
(2Z,NE)-N-benzylidene-4-(3,4-dimethoxyphenyl)-2-(phenylimino)thiazol-3(2H)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927187; BDBM50359725; STL264510; AKOS002238584; ST50113618; F0807-0342; (2Z)-4-(3,4-dimethoxyphenyl)-2-(phenylimino)-N-[(E)-phenylmethylidene]-1,3-thiazol-3(2H)-amine; 4-[3-((1E)-2-phenyl-1-azavinyl)-2-(phenylazamethylene)(1,3-thiazolin-4-yl)]-1, 2-dimethoxybenzene
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[36] | |||
| Compound Name |
N-Hydroxycarbamoylmethyl-N-(1-methyl-butyl)-2-[3-naphthalen-2-yl-1-(1,2,3,4-tetrahydro-naphthalen-1-yl)-ureido]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL98186; BDBM50081776
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[13] | |||
| Compound Name |
(S,E)-5-(3-Chlorophenylamino)-4-(3-(3,4-dimethoxyphenyl)acrylamido)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL477652; BDBM50267466
Click to Show/Hide
|
||||
| Activity |
IC50 = 120800 nM
|
[31] | |||
| Compound Name |
4-Thiouracil
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-Hydroxy-4(1H)-pyrimidinethione; 4-sulfanylidene-1H-pyrimidin-2-one; 2-Hydroxy-4-mercaptopyrimidine; 4-mercaptopyrimidin-2-ol; Uracil, 4-thio-; 4-Thiouracil, 97%; 2(1H)-pyrimidinone, 3,4-dihydro-4-thioxo-; 4-sulfanylpyrimidin-2-ol; 2-Hydroxy-4-thiopyrimidine; CHEMBL1650608; KC 135; MFCD00090842; 4-Thiouracyl; 4-thiopyrimidin-2-one; ACMC-1AXFO; 2(1H)-Pyrimidinone, 4-mercapto- (9CI); SCHEMBL26167; 2-Pyrimidinol, 4-mercapto-; SCHEMBL10524664; CTK1A1769; CTK5A9480; CTK8H5107; DTXSID50207840; KS-000010TK; NSC43288; ZINC5117659; ANW-33167; BBL101106; BDBM50335810; GEO-02327; NSC-43288; STL554902; TD8160; 4(3H)-Pyrimidinethione, 2-hydroxy-; AKOS005256998; AKOS006229660; AKOS015916356; AKOS015995934; MCULE-8582608477; 6-sulfanyl-1,2-dihydropyrimidin-2-one; 4-sulfanylidene-1~{H}-pyrimidin-2-one; AS-54718; SC-76314; 3,4-Dihydro-4-thioxo-2(1H)-pyrimidinone; 4-thioxo-3,4-dihydro-2(1H)-pyrimidinone; AB0101133; DB-053326; DB-066140; 2(1H)-Pyrimidinone,3,4-dihydro-4-thioxo-; FT-0619526; FT-0721260; ST51038365; Z2909; A-8137; T-3812; 268H535; A832178; W-201773; Q20892040; Benzenepropanoic acid, 2,4,6-trimethyl-.beta.-oxo-, ethyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 = 121000 nM
|
[10] | |||
| Compound Name |
(S)-Benzyl-2-(2-((S)-3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)-4-methylpentanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1213670; BDBM50323946
Click to Show/Hide
|
||||
| Activity |
IC50 = 121000 nM
|
[35] | |||
| Compound Name |
(2S)-2-Amino-N-[(3S)-1-[2-(4-fluoroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1214487; BDBM50323935
Click to Show/Hide
|
||||
| Activity |
IC50 = 122000 nM
|
[35] | |||
| Compound Name |
(R)-5-(2,5-Dichlorophenylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523936; BDBM50267961
Click to Show/Hide
|
||||
| Activity |
IC50 = 122400 nM
|
[21] | |||
| Compound Name |
3-Fluorobenzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254611; BDBM50227528
Click to Show/Hide
|
||||
| Activity |
IC50 = 124000 nM
|
[26] | |||
| Compound Name |
(2S)-N-(4-Fluorophenyl)-2-[[2-(3-methyl-2-oxoquinoxalin-1-yl)acetyl]amino]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL604737; BDBM50306917; (S)-N-(4-Fluorophenyl)-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamido)-3-phenyl-propanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 124320 nM
|
[25] | |||
| Compound Name |
(E)-5-(4-Hydroxyphenyl)-2-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]-3-oxo-N-phenylpent-4-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL2122254; CHEMBL3893144; US9187406, Compound 7; BDBM191770
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[41] | |||
| Compound Name |
2-[[4-[(3,5-Dibromophenyl)methoxy]phenyl]sulfonylamino]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2431023; BDBM50441229
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[63] | |||
| Compound Name |
Naphthalen-2-yl 6-oxo-1,6-dihydropyridine-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL253188; BDBM50227545
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[26] | |||
| Compound Name |
N-Benzyl-2-[1-cyclohexylmethyl-3-(4-phenoxy-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL418779; BDBM50081798
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[13] | |||
| Compound Name |
4-(Trifluoromethyl)benzyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL398662; BDBM50227544
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[26] | |||
| Compound Name |
Benzyl-3-(2-((S)-3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1213671; BDBM50323947
Click to Show/Hide
|
||||
| Activity |
IC50 = 127000 nM
|
[35] | |||
| Compound Name |
(S)-Benzyl-2-(2-(3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1213668; BDBM50323944
Click to Show/Hide
|
||||
| Activity |
IC50 = 129000 nM
|
[35] | |||
| Compound Name |
2-Cinnamamido-N1-hydroxy-N4-propylsuccinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL593542; BDBM50304546
Click to Show/Hide
|
||||
| Activity |
IC50 = 131000 nM
|
[11] | |||
| Compound Name |
(2S)-2-Amino-N-[(3S)-1-[2-(3-chloro-4-fluoroanilino)-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1214591; BDBM50323941
Click to Show/Hide
|
||||
| Activity |
IC50 = 131000 nM
|
[35] | |||
| Compound Name |
(2S)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819443; BDBM50351039
Click to Show/Hide
|
||||
| Activity |
IC50 = 133800 nM
|
[22] | |||
| Compound Name |
(2R)-2-Amino-N-[(3S)-1-[2-[[2-(hydroxyamino)-2-oxoethyl]amino]-2-oxoethyl]-2,6-dioxopiperidin-3-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1213798; BDBM50323957
Click to Show/Hide
|
||||
| Activity |
IC50 = 141000 nM
|
[35] | |||
| Compound Name |
(2S)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819322; BDBM50351048
Click to Show/Hide
|
||||
| Activity |
IC50 = 142900 nM
|
[22] | |||
| Compound Name |
1-Cinnamyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249249; BDBM50227597
Click to Show/Hide
|
||||
| Activity |
IC50 = 149000 nM
|
[26] | |||
| Compound Name |
(2R)-2-Amino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819336; BDBM50351037
Click to Show/Hide
|
||||
| Activity |
IC50 = 149200 nM
|
[22] | |||
| Compound Name |
3-((2-Phenethyl-2H-tetrazol-5-yl)methyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251465; BDBM50227530
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
4-(4,5-Dihydrooxazol-2-yl)-1-phenethyl-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400851; BDBM50227577
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
1-Cyclohexenyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249860; BDBM50227560
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
2-[1-Tert-Butyl-3-(4-phenoxy-phenyl)-ureido]-N-cyclohexylmethyl-N-hydroxycarbamoylmethyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329696; BDBM50081800
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[13] | |||
| Compound Name |
4-(4,5-Dihydrooxazol-2-yl)-1-(3-phenylpropyl)-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249863; BDBM50227536
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
3-((2-Benzyl-2H-tetrazol-5-yl)methyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400357; BDBM50227573
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
4-(4,5-Dihydrooxazol-2-yl)-1-hexyl-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249861; BDBM50227550
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
Isopropyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL404205; BDBM50227591
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
(E)-3-((2-Cinnamyl-2H-tetrazol-5-yl)methyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL428762; BDBM50227546
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
4-(4,5-Dihydrooxazol-2-yl)-1-heptyl-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400850; BDBM50227570
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
1-Benzyl-4-(4,5-dihydrooxazol-2-yl)-1H-1,2,3-triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249862; BDBM50227566; J3.517.457E; 1-Benzyl-4-(2-oxazoline-2-yl)-1H-1,2,3-triazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
Cyclobutyl 6-mercaptopicolinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL252327; BDBM50227539
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
3-((2-(3-Phenylpropyl)-2H-tetrazol-5-yl)methyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400358; BDBM50227594
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[26] | |||
| Compound Name |
N-Tert-Butyl-N-hydroxycarbamoylmethyl-2-[3-(2-methylsulfanyl-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97293; BDBM50081769
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[13] | |||
| Compound Name |
[Heptyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL321088; BDBM50081794; N-Heptyl-N-hydroxycarbamoylmethyl-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[13] | |||
| Compound Name |
(2S)-2-Amino-3-methyl-N-[(2R)-2-amino-3-phenylpropyl]propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457427; BDBM50273632
Click to Show/Hide
|
||||
| Activity |
IC50 = 151400 nM
|
[45] | |||
| Compound Name |
(2R)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-3-sulfanylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819319; BDBM50351023
Click to Show/Hide
|
||||
| Activity |
IC50 = 151600 nM
|
[22] | |||
| Compound Name |
[(4S,5S)-2-((Z)-4-Phenyl-buta-1,3-dienyl)-5-vinyl-4,5-dihydro-oxazol-4-yl]-methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL187079; BDBM50152645
Click to Show/Hide
|
||||
| Activity |
Ki = 153000 nM
|
[47] | |||
| Compound Name |
N-Tert-Butyl-N-hydroxycarbamoylmethyl-2-[1-isopropyl-3-(4-phenoxy-phenyl)-ureido]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94796; BDBM50081772
Click to Show/Hide
|
||||
| Activity |
IC50 = 155000 nM
|
[13] | |||
| Compound Name |
(S)-2-(2-(3-((S)-2-Amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1213733; BDBM50323951
Click to Show/Hide
|
||||
| Activity |
IC50 = 155000 nM
|
[35] | |||
| Compound Name |
(2S)-2,6-Diamino-N-[(2S,3S)-2-amino-3-(4-aminophenyl)-3-hydroxypropyl]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819335; BDBM50351036
Click to Show/Hide
|
||||
| Activity |
IC50 = 157400 nM
|
[22] | |||
| Compound Name |
(2S)-N-Hydroxy-1-[(3S)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl]pyrrolidine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830657
Click to Show/Hide
|
||||
| Activity |
IC50 = 157420 nM
|
[64] | |||
| Compound Name |
(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(methylamino)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL491451; BDBM50267525
Click to Show/Hide
|
||||
| Activity |
IC50 = 159100 nM
|
[31] | |||
| Compound Name |
N'-[2-(3-Methyl-2-oxo-quinoxalin-1-yl)acetyl]-2-phenyl-acetohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775319; BDBM50155277
Click to Show/Hide
|
||||
| Activity |
IC50 = 159390 nM
|
[30] | |||
| Compound Name |
N-[1-(Phenylthiomethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39358; SCHEMBL7498355; BDBM50100913; N-[1-(4''-Cyano-biphenyl-4-yloxymethyl)-2-phenylsulfanyl-ethyl]-N-hydroxy-formamide; N-[1-[4-(4-cyanophenyl)phenoxy]-3-phenylsulfanylpropan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 160000 nM
|
[27] | |||
| Compound Name |
N-Hydroxycarbamoylmethyl-2-[1-(1-methyl-butyl)-3-(4-phenoxy-phenyl)-ureido]-N-pentyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94268; BDBM50081773
Click to Show/Hide
|
||||
| Activity |
IC50 = 160000 nM
|
[13] | |||
| Compound Name |
(3S)-N-[(2S)-1-(Hydroxyamino)-4-methylsulfanyl-1-oxobutan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830654
Click to Show/Hide
|
||||
| Activity |
IC50 = 166110 nM
|
[64] | |||
| Compound Name |
2-Cinnamamido-N1-hydroxy-N4-isopropylsuccinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL593795; BDBM50304539
Click to Show/Hide
|
||||
| Activity |
IC50 = 166600 nM
|
[11] | |||
| Compound Name |
(R)-5-Oxo-5-(2-(thiazole-2-carbonyl)hydrazinyl)-4-(3,4,5-trimethoxybenzamido)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL490844; BDBM50267880
Click to Show/Hide
|
||||
| Activity |
IC50 = 169400 nM
|
[21] | |||
| Compound Name |
N6-[(Benzyloxy)carbonyl]-N2-(2,4-dichlorobenzoyl)-N1-hydroxy-L-lysinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL500911; BDBM50271955
Click to Show/Hide
|
||||
| Activity |
IC50 = 170000 nM
|
[17] | |||
| Compound Name |
(2S)-2-Amino-4-methyl-N-[(2R)-2-amino-3-phenylpropyl]valeramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL505762; BDBM50273631
Click to Show/Hide
|
||||
| Activity |
IC50 = 170200 nM
|
[45] | |||
| Compound Name |
(2S)-2-Amino-N-[(2R)-1-[[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819328; BDBM50351029
Click to Show/Hide
|
||||
| Activity |
IC50 = 173100 nM
|
[22] | |||
| Compound Name |
2-Cinnamamido-4-(dodecylamino)-4-oxobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL594941; BDBM50304562
Click to Show/Hide
|
||||
| Activity |
IC50 = 176500 nM
|
[11] | |||
| Compound Name |
L-Phenylalanyl-N-[(2R)-2-amino-3-phenylpropyl]-L-phenylalaninamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457447; BDBM50273773; CHEMBL493555; BDBM50257208
Click to Show/Hide
|
||||
| Activity |
IC50 = 182900 nM
|
[45] | |||
| Compound Name |
N'-[2-(3-Methyl-2-oxo-quinoxalin-1-yl)acetyl]benzohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775713; BDBM50155276
Click to Show/Hide
|
||||
| Activity |
IC50 = 187410 nM
|
[30] | |||
| Compound Name |
N4-(4-Chlorophenyl)-2-cinnamamido-N1-hydroxysuccinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL595881; BDBM50304535
Click to Show/Hide
|
||||
| Activity |
IC50 = 196600 nM
|
[11] | |||
| Compound Name |
N-Benzhydryl-N-hydroxycarbamoylmethyl-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL318122; BDBM50081779; N-Hydroxy-2-[benzhydryl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[13] | |||
| Compound Name |
(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-trifluoromethoxy-phenylsulfanyl)-propyl]-phosphinic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL323885; BDBM50138686
Click to Show/Hide
|
||||
| Activity |
Ki = 200000 nM
|
[65] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 127 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N4-Butyl-2-cinnamamido-N1-hydroxysuccinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL596553; N4-Butyl-2-cinnamamido-N1-hydroxysuccinamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 232500 nM
|
[11] | |||
| Compound Name |
2-Cinnamamido-N1-hydroxy-N4-octylsuccinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL594848; 2-Cinnamamido-N1-hydroxy-N4-octylsuccinamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 285900 nM
|
[11] | |||
| Compound Name |
3-Hydroxy-N-methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL251901; BDBM50241377; (S)-3-Hydroxy-N-methyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[59] | |||
| Compound Name |
6-Methylquinoline-8-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4101230; 6-Methyl-8-mercaptochinolin; 8-Quinolinethiol, 6-methyl-; SCHEMBL18526845; BDBM50264491
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[66] | |||
| Compound Name |
3-Methylquinoline-8-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4100994; 8-Quinolinethiol, 3-methyl-; 3-methyl-8-quinolinethiol; SCHEMBL3067414; BDBM50264503
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[66] | |||
| Compound Name |
2-Methylquinoline-8-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
8-Quinolinethiol, 2-methyl-; CHEMBL4083010; 2-methyl-8-mercaptochinolin; SCHEMBL1914441; CTK0G7734; DTXSID80461554; BDBM50264502; ZINC12462690
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[66] | |||
| Compound Name |
[(2S)-3-[[(2S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-oxo-2-[2-(trifluoromethoxy)phenyl]sulfanylpropyl]-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphinic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2153738; BDBM50393207
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[67] | |||
| Compound Name |
5-Methylquinoline-8-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
8-Quinolinethiol, 5-methyl-; CHEMBL4084782; 5-methyl-8-quinolinethiol; SCHEMBL13977568; CTK1H9946; DTXSID70500764; BDBM50264484
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[66] | |||
| Compound Name |
(S)-3-Phenyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39553; SCHEMBL6953038; BDBM50076343; ZINC13796963; (2S)-3-phenyl-2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)carbamoylamino]propanamide; (S)-alpha-[3-[(5-Thioxo-4,5-dihydro-1,3,4-thiadiazol)-2-yl]ureido]benzenepropanamide
Click to Show/Hide
|
||||
| Activity |
Ki > 200000 nM
|
[59] | |||
| Compound Name |
4-Methylquinoline-8-thiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
8-Quinolinethiol, 4-methyl-; CHEMBL4063134; 4-methyl-8-quinolinethiol; SCHEMBL15703126; CTK0B7293; DTXSID80492580; BDBM50264490
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[66] | |||
| Compound Name |
8-Mercaptoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
quinoline-8-thiol; 8-Quinolinethiol; SQT-8; 8-thioquinoline; [S]c1cccc2cccnc12; 8-Mercaptoquinoline (8TQ); NCIOpen2_001790; SCHEMBL536578; CHEMBL4076575; DTXSID70197678; BDBM224013; HMS1788G22; ZINC389710; NSC48888; NSC-48888; AKOS022191814; AKOS024342879; MCULE-9204136169; DB-070965; FT-0735097; MLS-0472512.0001; 8-Quinolinethiol;Quinoline-8-thiol;8-Thioquinoline; F9994-0398
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[66] | |||
| Compound Name |
Chembl1830656
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2369772; BDBM50353917
Click to Show/Hide
|
||||
| Activity |
IC50 = 200630 nM
|
[64] | |||
| Compound Name |
(2S)-2-Amino-3-hydroxyl-N-[(2R)-2-amino-3-phenylpropyl]propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL458083; BDBM50273665
Click to Show/Hide
|
||||
| Activity |
IC50 = 201900 nM
|
[45] | |||
| Compound Name |
Chembl4217681
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50457483
Click to Show/Hide
|
||||
| Activity |
IC50 = 203400 nM
|
[68] | |||
| Compound Name |
Ethyl 5-(methanesulfonamido)-1H-indole-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939861; SCHEMBL8408444; BDBM50361619
Click to Show/Hide
|
||||
| Activity |
IC50 = 210000 nM
|
[34] | |||
| Compound Name |
(8S)-7-(4-Methylphenyl)sulfonyl-N-[(E)-(3,4,5-trimethoxyphenyl)methylideneamino]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775720; BDBM50155525
Click to Show/Hide
|
||||
| Activity |
IC50 = 210410 nM
|
[30] | |||
| Compound Name |
(2E)-N-[(2R)-2-Amino-3-phenylpropyl]-3-phenylacrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL451473; BDBM50273693
Click to Show/Hide
|
||||
| Activity |
IC50 = 211300 nM
|
[45] | |||
| Compound Name |
(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(ethylamino)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL491650; BDBM50267526
Click to Show/Hide
|
||||
| Activity |
IC50 = 211400 nM
|
[31] | |||
| Compound Name |
(2S)-2,5-Amino-N-[(2R)-2-amino-3-phenylpropyl]-valeramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457656; BDBM50273666
Click to Show/Hide
|
||||
| Activity |
IC50 = 219400 nM
|
[45] | |||
| Compound Name |
N-[(2R)-2-Amino-3-phenylpropyl]-4-phenylbutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459757; BDBM50273695
Click to Show/Hide
|
||||
| Activity |
IC50 = 221000 nM
|
[45] | |||
| Compound Name |
2-(3-Methyl-2-oxoquinoxalin-1-yl)-N-[(E)-(3,4,5-trimethoxyphenyl)methylideneamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775970; BDBM50155519; 2-(3-methyl-2-oxo-quinoxalin-1-yl)-N-[(E)-(3,4,5-trimethoxyphenyl)methyleneamino]acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 223370 nM
|
[30] | |||
| Compound Name |
(S)-N,N-Dimethyl-3-phenyl-2-[3-(5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-ureido]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40034; SCHEMBL6951421; BDBM50076370; ZINC13796965; (2S)-N,N-dimethyl-3-phenyl-2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)carbamoylamino]propanamide; (S)-N,N-Dimethyl-alpha-[3-[(5-thioxo-4,5-dihydro-1,3,4-thiadiazol)-2-yl]ureido]benzenepropanamide
Click to Show/Hide
|
||||
| Activity |
Ki = 226000 nM
|
[59] | |||
| Compound Name |
Chembl4202548
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455850
Click to Show/Hide
|
||||
| Activity |
IC50 = 230000 nM
|
[69] | |||
| Compound Name |
[Butyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328607; BDBM50081774; N-Butyl-N-hydroxycarbamoylmethyl-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 230000 nM
|
[13] | |||
| Compound Name |
(S,E)-5-(Benzylamino)-4-(3-(3,4-dimethoxyphenyl)-acrylamido)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL491450; BDBM50267524
Click to Show/Hide
|
||||
| Activity |
IC50 = 235800 nM
|
[31] | |||
| Compound Name |
2-(3-Methyl-2-oxo-quinoxalin-1-yl)-N-[(E)-(4-nitrophenyl)methyleneamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775708; BDBM50155291
Click to Show/Hide
|
||||
| Activity |
IC50 = 246260 nM
|
[30] | |||
| Compound Name |
(3S)-N-[2-(Hydroxyamino)-2-oxoethyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830511
Click to Show/Hide
|
||||
| Activity |
IC50 = 249240 nM
|
[64] | |||
| Compound Name |
(1E,6E)-1-[4-[(Dimethylamino)methyl]phenyl]-7-(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3963341; US9187406, Compound 4; BDBM191768
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[41] | |||
| Compound Name |
(3S)-N-[4-(Hydroxyamino)-4-oxobutyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830510
Click to Show/Hide
|
||||
| Activity |
IC50 = 251910 nM
|
[64] | |||
| Compound Name |
(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-(isopropylamino)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL490438; BDBM50267528
Click to Show/Hide
|
||||
| Activity |
IC50 = 256100 nM
|
[31] | |||
| Compound Name |
N-[1-(Phenoxymethyl)-2-(4'-cyano-4-biphenylyloxy)ethyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41485; SCHEMBL7504451; BDBM50100907; N-[1-[4-(4-cyanophenyl)phenoxy]-3-phenoxypropan-2-yl]-N-hydroxyformamide; N-[2-(4''-Cyano-biphenyl-4-yloxy)-1-phenoxymethyl-ethyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 260000 nM
|
[27] | |||
| Compound Name |
(3S)-N-[(2S)-3-Hydroxy-1-(hydroxyamino)-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830655
Click to Show/Hide
|
||||
| Activity |
IC50 = 267730 nM
|
[64] | |||
| Compound Name |
Dibenzyl (2S)-2-[[2-[(3S)-3-[[(2S)-2-amino-3-phenylpropanoyl]amino]-2,6-dioxopiperidin-1-yl]acetyl]amino]pentanedioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1213731; BDBM50323949
Click to Show/Hide
|
||||
| Activity |
IC50 = 272000 nM
|
[35] | |||
| Compound Name |
(2S,4R)-N,4-Dihydroxy-1-[(3S)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl]pyrrolidine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830658
Click to Show/Hide
|
||||
| Activity |
IC50 = 276440 nM
|
[64] | |||
| Compound Name |
(S,E)-4-(3-(3,4-Dimethoxyphenyl)acrylamido)-5-oxo-5-(propylamino)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL491651; BDBM50267527
Click to Show/Hide
|
||||
| Activity |
IC50 = 283600 nM
|
[31] | |||
| Compound Name |
(R)-5-(3-Bromobenzylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL477251; BDBM50267318
Click to Show/Hide
|
||||
| Activity |
IC50 = 287300 nM
|
[21] | |||
| Compound Name |
(2R)-5-Oxo-1-[(4-phenylphenyl)methyl]pyrrolidine-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957576; BDBM50366177
Click to Show/Hide
|
||||
| Activity |
IC50 = 290000 nM
|
[70] | |||
| Compound Name |
(2R)-2-[[(E)-3-(4-Methoxyphenyl)prop-2-enoyl]amino]-N-[5-(4-nitrophenyl)-1,3,4-thiadiazol-2-yl]propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL481704; BDBM50251877; (2R)-N-[5-(4-Nitrorophenyl)-1,3,4-thiadiazol-2-yl]-2-[(pmethoxycinnamoyl)amino]-propanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 297300 nM
|
[71] | |||
| Compound Name |
L-Leucyl-L-phenylalanine methylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL445994; h-leu-phe-nhme, AldrichCPR; SCHEMBL7330972; ZINC2386645; BDBM50245250; MFCD01862383; L-leucyl-L-phenylalanine N-methylamide; (2S)-2-AMINO-4-METHYL-N-[(1S)-1-(METHYLCARBAMOYL)-2-PHENYLETHYL]PENTANAMIDE; (2S)-2-amino-4-methyl-N-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]pentanamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[33] | |||
| Compound Name |
N-[(Hydroxyamino)carbonyl]-D-leucyl-Lphenylalanine methylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL452082; BDBM50245247
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[33] | |||
| Compound Name |
D-Leucyl-L-phenylalanine methylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL510082; BDBM50245251
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[33] | |||
| Compound Name |
Z-L-Leu-L-Phe-OMe
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL452584; SCHEMBL7326037; BDBM50245249; N-benzyloxycarbonyl-L-leucyl-L-phenylalanine methyl ester; N-(Benzyloxycarbonyl)-L-leucyl-L-phenylalanine methyl ester; methyl (2S)-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-3-phenylpropanoate
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[33] | |||
| Compound Name |
(3S)-N-[(2S)-1-(Hydroxyamino)-3-methyl-1-oxobutan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830648
Click to Show/Hide
|
||||
| Activity |
IC50 = 307270 nM
|
[64] | |||
| Compound Name |
5-Pyridin-4-yl-1H-indole-2-carboxylic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939870; SCHEMBL15642864; BDBM50361628; DB-124067; ethyl 5-pyridin-4-yl-1H-indole-2-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 = 310000 nM
|
[34] | |||
| Compound Name |
(2S)-1-[(2-Chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL243307; ZINC266791; BDBM50366189; AKOS024405262
Click to Show/Hide
|
||||
| Activity |
IC50 = 315000 nM
|
[70] | |||
| Compound Name |
(S)-2-(2-((S)-3-((S)-2-Amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl)acetamido)-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1213796; BDBM50323955
Click to Show/Hide
|
||||
| Activity |
IC50 = 315650 nM
|
[35] | |||
| Compound Name |
2-Cinnamamido-N1-hydroxy-N4-phenylsuccinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL594936; BDBM50304544
Click to Show/Hide
|
||||
| Activity |
IC50 = 324400 nM
|
[11] | |||
| Compound Name |
(2E)-N-[(2R)-2-Amino-3-phenylpropyl]-3-(3,4-hydroxy)-acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL445758; BDBM50273697
Click to Show/Hide
|
||||
| Activity |
IC50 = 328500 nM
|
[45] | |||
| Compound Name |
(4R)-N-Hydroxy-3-[(4-phenylphenyl)methyl]-1,3-thiazolidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957593; BDBM50366195
Click to Show/Hide
|
||||
| Activity |
IC50 = 330000 nM
|
[70] | |||
| Compound Name |
(2S)-2-Amino-N-[(2S,3S)-2-amino-3-hydroxy-3-(4-nitrophenyl)propyl]-3-hydroxypropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1819320; BDBM50351021
Click to Show/Hide
|
||||
| Activity |
IC50 = 331100 nM
|
[22] | |||
| Compound Name |
(2S)-5-Oxo-1-[(4-phenylphenyl)methyl]pyrrolidine-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957585; BDBM50366186
Click to Show/Hide
|
||||
| Activity |
IC50 = 340000 nM
|
[70] | |||
| Compound Name |
Dimethyl 2-[[(4S)-5-[(1,4-dimethoxy-1,4-dioxobutan-2-yl)amino]-4-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]-5-oxopentanoyl]amino]butanedioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL451393; BDBM50267680; (S,E)-2-[3-(3,4-Dimethoxyphenyl)acrylamido]-N1,N5-[(R)-1,4-dimethoxy-1,4-dioxobutan]pentanediamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 340800 nM
|
[31] | |||
| Compound Name |
(E)-2-(5-((5-(4-Methoxyphenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927186; ZINC2698193; BDBM50359724; STK711873; AKOS002386597; ST50326453; AB00674549-01; F1542-0089
Click to Show/Hide
|
||||
| Activity |
IC50 = 350000 nM
|
[36] | |||
| Compound Name |
(S,E)-2-(3-(3,4-Dimethoxyphenyl)acrylamido)-N1,N5-bis(4-fluorophenyl)pentanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL489238; BDBM50267610
Click to Show/Hide
|
||||
| Activity |
IC50 = 368100 nM
|
[31] | |||
| Compound Name |
(R)-5-Oxo-5-(thiazol-2-ylamino)-4-(3,4,5-trimethoxybenzamido)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL491854; BDBM50267879
Click to Show/Hide
|
||||
| Activity |
IC50 = 369400 nM
|
[21] | |||
| Compound Name |
N-Sec-Butyl-N-hydroxycarbamoylmethyl-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL93768; BDBM50081795; N-Hydroxy-2-[sec-butyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 370000 nM
|
[13] | |||
| Compound Name |
1-(4-Phenoxyphenethyl)-3-hydroxyurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL197921; BDBM50175781
Click to Show/Hide
|
||||
| Activity |
IC50 > 380000 nM
|
[29] | |||
| Compound Name |
L-Proline, 1-((4-chlorophenyl)methyl)-5-oxo-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-((4-Chlorophenyl)methyl)-5-oxo-L-proline; CHEMBL1957590; Acide N-(p-chlorobenzyl)pyroglutamique [French]; Acide N-(p-chlorobenzyl)pyroglutamique; SCHEMBL16601331; CTK3I9291; DTXSID40208467; ZINC6092884; (2S)-1-[(4-chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxylic acid; BDBM50366192; 1-(4-Chlorobenzyl)-5-oxo-L-proline; (S)-1-(4-Chlorobenzyl)-5-oxopyrrolidine-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 383000 nM
|
[70] | |||
| Compound Name |
3-Aminosalicylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-Amino-2-hydroxybenzoic acid; 3-amino salicylic acid; Benzoic acid, 3-amino-2-hydroxy-; MFCD00010299; 3-amino-2-hydroxy-benzoic acid; UNII-WN7T1GM9RM; WN7T1GM9RM; Salicylic acid, 3-amino-; 3-Aminosalicylic acid, 97%; CHEMBL1650630; 3-Amino-2-hydroxybenzoic acid (3-Aminosalicylic acid); 3-amino-2-hydroxybenzoate; Benzoic acid, amino-2-hydroxy-; 3-Aminosalicylate; 3-amino-salicylate; 3-Amino Salicylate; EINECS 209-328-0; Mesalamine Impurity F; NSC 285111; 3-aminosalicyclic acid; 3-amino-salicylic acid; PubChem14474; 3-amino-(8CI)salicylate; ACMC-1B1LK; 3-amino-2-hydroxy-benzoate; Oprea1_451884; Benzoicacid,amino-2-hydroxy-; 3-amino-(8CI)salicylic acid; SCHEMBL204392; 2-hydroxy 3-aminobenzoic acid; 3-AMINOSALICYLIC ACID,; 2-hydroxy 3-amino benzoic acid; CTK0J2212; ZINC88619; DTXSID90862215; 3-Amino-2-hydroxybenzoic acid #; KUC106692N; 3-amino-2-hydroxy-(9CI)benzoate; Salicylic acid, 3-amino- (8CI); ANW-32621; BDBM50335811; NSC285111; SBB001895; STK677269; 3-amino-2-hydroxy-(9CI)benzoic acid; AKOS005594690; AB01026; MCULE-1378878669; NSC-285111; PS-5956; VZ26258; AC-23862; SC-14094; Benzoic acid, 3-amino-2-hydroxy- (9CI); KSC-11-207-24; ST4062832; A0421; AM20080689; FT-0615072; FT-0619948; X8030; A-8661; 088A644; 570A230; W-105491; Q27161513
Click to Show/Hide
|
||||
| Activity |
IC50 = 389000 nM
|
[10] | |||
| Compound Name |
(3S)-N-[(1S)-2-(Hydroxyamino)-2-oxo-1-phenylethyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830651
Click to Show/Hide
|
||||
| Activity |
IC50 = 393140 nM
|
[64] | |||
| Compound Name |
(S,E)-2-(3-(3,4-Dimethoxyphenyl)acrylamido)-N1,N5-dip-tolylpentanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL489237; BDBM50267609
Click to Show/Hide
|
||||
| Activity |
IC50 = 397600 nM
|
[31] | |||
| Compound Name |
(2R)-1-[(4-Chlorophenyl)methyl]-N-hydroxy-5-oxopyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957581; BDBM50366182
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[70] | |||
| Compound Name |
(8S)-7-(4-Methylphenyl)sulfonyl-1,4-dithia-7-azaspiro[4.4]nonane-8-carbohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3092092; BDBM50155524; (2S)-3-(p-tolylsulfonyl)-6,9-dithia-3-azaspiro[4.4]nonane-2-carbohydrazide
Click to Show/Hide
|
||||
| Activity |
IC50 = 428990 nM
|
[43] | |||
| Compound Name |
N4-Benzyl-2-cinnamamido-N1-hydroxysuccinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL594961; BDBM50304537
Click to Show/Hide
|
||||
| Activity |
IC50 = 447200 nM
|
[11] | |||
| Compound Name |
Benzyl 2-[[2-[(3S)-3-[[(2S)-2-amino-3-phenylpropanoyl]amino]-2,6-dioxopiperidin-1-yl]acetyl]amino]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1214593; BDBM50323943; (S)-Benzyl-2-(2-(3-((S)-2-amino-3-phenylpropanamido)-2,6-dioxopiperidin-1-yl))acetate
Click to Show/Hide
|
||||
| Activity |
IC50 = 454000 nM
|
[35] | |||
| Compound Name |
(3S)-N-[(2S)-1-(Hydroxyamino)-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830512
Click to Show/Hide
|
||||
| Activity |
IC50 = 463380 nM
|
[64] | |||
| Compound Name |
(S,E)-N1,N5-Bis(4-chlorophenyl)-2-(3-(3,4-dimethoxyphenyl)acrylamido)pentanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL490452; BDBM50267643
Click to Show/Hide
|
||||
| Activity |
IC50 = 470600 nM
|
[31] | |||
| Compound Name |
(S,E)-2-(3-(3,4-Dimethoxyphenyl)acrylamido)-N1,N5-bis(2-fluorophenyl)pentanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL490647; BDBM50267645
Click to Show/Hide
|
||||
| Activity |
IC50 = 470700 nM
|
[31] | |||
| Compound Name |
N-[2-[4-(4-Cyanophenyl)phenoxy]-1-(4-fluorophenyl)ethyl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39035; SCHEMBL7505043; BDBM50100906; N-[2-(4''-Cyano-biphenyl-4-yloxy)-1-(4-fluoro-phenyl)-ethyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 480000 nM
|
[27] | |||
| Compound Name |
[Isopropyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97552; BDBM50081787; N-Hydroxycarbamoylmethyl-N-isopropyl-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[13] | |||
| Compound Name |
(2S,4R)-N,4-Dihydroxy-1-[(4-phenylphenyl)methyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957594; BDBM50366196
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
[Cyclohexylmethyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL96443; BDBM50081770
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[13] | |||
| Compound Name |
(2S)-N-Hydroxy-4-methylsulfanyl-2-(2-phenylethylcarbamoylamino)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2036155; BDBM50385336
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[72] | |||
| Compound Name |
Ethyl 5-{1-methyl-3-[(pyridin-4-ylmethyl)carbamoyl]-1H-pyrazol-5-yl}-1H-indole-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939874; SCHEMBL1313866; BDBM50361632; DB-124923; ethyl 5-[2-methyl-5-(pyridin-4-ylmethylcarbamoyl)pyrazol-3-yl]-1H-indole-2-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[34] | |||
| Compound Name |
2-N-Ethyl-1H-indole-2,5-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939864; BDBM50361622
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[34] | |||
| Compound Name |
(2S)-2-(Benzylcarbamoylamino)-N-hydroxy-4-methylsulfanylbutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2036148; BDBM50385329
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[72] | |||
| Compound Name |
(2R)-1-[(2-Chlorophenyl)methyl]-N-hydroxy-5-oxopyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957578; BDBM50366179
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
Ethyl 5-acetamido-1H-indole-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939865; 1H-Indole-2-carboxylic acid, 5-(acetylamino)-, ethyl ester; ACMC-20mdru; Oprea1_783119; SCHEMBL6514040; CTK0G1996; DTXSID50350643; BDBM50361623; Ethyl 5-acetaminoindole-2-carboxylate; ethyl 5-acetylaminoindole-2-carboxylate; SR-01000519056; SR-01000519056-1
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[34] | |||
| Compound Name |
(2S)-5-Oxo-1-[(4-phenylphenyl)methyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957586; BDBM50366187
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
[Tert-Butyl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL95679; BDBM50081781; N-tert-Butyl-N-hydroxycarbamoylmethyl-2-[3-(4-phenoxy-phenyl)-1-(3-phenyl-propyl)-ureido]-acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[13] | |||
| Compound Name |
(2S)-2-(Benzylcarbamoylamino)-N-hydroxy-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2036147; BDBM50385328
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[72] | |||
| Compound Name |
2-[1-Benzhydryl-3-(4-butoxy-phenyl)-ureido]-N-heptyl-N-hydroxycarbamoylmethyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97175; BDBM50081791
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[13] | |||
| Compound Name |
(2R)-5-Oxo-1-[(4-phenylphenyl)methyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957577; BDBM50366178
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
Ethyl 5-(3-methylpyridin-4-yl)-1H-indole-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939871; BDBM50361629
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[34] | |||
| Compound Name |
Ethyl 5-pyridin-2-yl-1H-indole-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939868; BDBM50361626
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[34] | |||
| Compound Name |
[Tetralin-1-yl[1-(3-phenylpropyl)-3-(4-phenoxyphenyl)ureidoacetyl]amino]acetohydroximic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL262693; BDBM50081784
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[13] | |||
| Compound Name |
(2S)-2-(Benzylcarbamoylamino)-N-hydroxy-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2393088; BDBM50435266
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[73] | |||
| Compound Name |
N-[2-(4,5-Dihydro-1,3-oxazol-2-yl)-1H-indol-5-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939866; BDBM50361624
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[34] | |||
| Compound Name |
(2R)-1-[(2-Chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957580; BDBM50366181
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
2-[3-(5-Chloro-2-methoxy-phenyl)-1-(4-phenyl-butyl)-ureido]-N-hydroxycarbamoylmethyl-N-pentyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL95781; BDBM50081789
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[13] | |||
| Compound Name |
2-Butanoyl-1H-indole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939863; BDBM50361621
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[34] | |||
| Compound Name |
(2S,3S)-2-(Benzylcarbamoylamino)-N-hydroxy-3-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2036146; BDBM50385316
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[72] | |||
| Compound Name |
(2S)-1-[(2-Chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957588; BDBM50366190
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
(2S)-N-Hydroxy-1-[(4-phenylphenyl)methyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957592; BDBM50366194
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
N-Butyl-2-[1-cyclohexylmethyl-3-(2-methyl-4-nitro-phenyl)-ureido]-N-hydroxycarbamoylmethyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL96447; BDBM50081777
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[13] | |||
| Compound Name |
(2S)-1-[(4-Chlorophenyl)methyl]-N-hydroxy-5-oxopyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957589; BDBM50366191
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
N'-Acetyl-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3774559; BDBM50155275
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[30] | |||
| Compound Name |
Ethyl 5-phenyl-1H-indole-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1939867; 5-phenyl-2-carbethoxyindole; SCHEMBL419130; CTK1H9732; DTXSID30496679; BDBM50361625; 5-Phenyl-1H-indole-2-carboxylic Acid Ethyl Ester; 1H-Indole-2-carboxylic acid, 5-phenyl-, ethyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[34] | |||
| Compound Name |
(R)-1-(4-Chlorobenzyl)-5-oxopyrrolidine-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957582; SCHEMBL19975206; ZINC6092885; BDBM50366183; (2R)-1-[(4-chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
(2R)-1-[(4-Chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957583; BDBM50366184
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
(2S)-N-Hydroxy-4-methyl-2-(2-phenylethylcarbamoylamino)pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2036152; BDBM50385333
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[72] | |||
| Compound Name |
(2S)-1-[(2-Chlorophenyl)methyl]-N-hydroxy-5-oxopyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957587; BDBM50366188
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
(2S)-1-[(4-Chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957591; BDBM50366193
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
D-Proline,1-[(2-chlorophenyl)methyl]-5-oxo-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1957579; SCHEMBL1613178; ZINC266790; BDBM50366180; (R)-1-(2-chlorobenzyl)-5-oxopyrrolidine-2-carboxylic acid; (2R)-1-[(2-chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[70] | |||
| Compound Name |
(R)-5-(2-Chloroethylamino)-5-oxo-4-(3,4,5-trimethoxybenzamido)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL476868; BDBM50267433
Click to Show/Hide
|
||||
| Activity |
IC50 = 501500 nM
|
[21] | |||
| Compound Name |
(3S)-N-[3-(Hydroxyamino)-3-oxopropyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830509
Click to Show/Hide
|
||||
| Activity |
IC50 = 516830 nM
|
[64] | |||
| Compound Name |
(3S)-N-[(2S)-1-(Hydroxyamino)-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830653
Click to Show/Hide
|
||||
| Activity |
IC50 = 540030 nM
|
[64] | |||
| Compound Name |
(2S)-N-Hydroxy-4-methyl-2-(naphthalen-1-ylmethylcarbamoylamino)pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2204959; BDBM50400532
Click to Show/Hide
|
||||
| Activity |
IC50 = 545000 nM
|
[74] | |||
| Compound Name |
N-[(2R)-2-Amino-3-phenylpropyl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459540; BDBM50273672
Click to Show/Hide
|
||||
| Activity |
IC50 = 546800 nM
|
[45] | |||
| Compound Name |
N-[(E)-1-(3-Chlorophenyl)ethylideneamino]-2-(3-methyl-2-oxoquinoxalin-1-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3775542; BDBM50155284; N-[(E)-1-(3-chlorophenyl)ethylideneamino]-2-(3-methyl-2-oxo-quinoxalin-1-yl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 566890 nM
|
[30] | |||
| Compound Name |
(2S)-N-Hydroxy-4-methyl-2-[(4-methylphenyl)carbamoylamino]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2204947; BDBM50400544
Click to Show/Hide
|
||||
| Activity |
IC50 = 573000 nM
|
[74] | |||
| Compound Name |
4-(Butylamino)-2-cinnamamido-4-oxobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL595871; BDBM50304563
Click to Show/Hide
|
||||
| Activity |
IC50 = 594300 nM
|
[11] | |||
| Compound Name |
[(4S,5S)-2-(4-Bromo-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl]-methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL181707; BDBM50152634
Click to Show/Hide
|
||||
| Activity |
Ki > 600000 nM
|
[47] | |||
| Compound Name |
(2S)-N-(4-Chlorophenyl)-2-[[2-(3-methyl-2-oxoquinoxalin-1-yl)acetyl]amino]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL599311; BDBM50306918; (S)-N-(4-Chlorophenyl)-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamido)-3-phenyl-propanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 624480 nM
|
[25] | |||
| Compound Name |
(R)-5-[4-(Aminosulfonyl)phenylamino]-5-oxo-4-[(3,4,5-trimethoxybenzamido)amino]pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL482633; BDBM50267842
Click to Show/Hide
|
||||
| Activity |
IC50 = 628000 nM
|
[21] | |||
| Compound Name |
N-[(2R)-2-Amino-3-phenylpropyl]-2-phenylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL511865; BDBM50273694
Click to Show/Hide
|
||||
| Activity |
IC50 = 632400 nM
|
[45] | |||
| Compound Name |
N-[1-[4-(4-Cyanophenyl)phenoxy]-3-(4-fluorophenyl)propan-2-yl]-N-hydroxyformamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289108; SCHEMBL7504912; BDBM50100901; N-[1-(4''-Cyano-biphenyl-4-yloxymethyl)-2-(4-fluoro-phenyl)-ethyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 650000 nM
|
[27] | |||
| Compound Name |
(3S)-N-[(2S)-1-[[(2S)-1-(Hydroxyamino)-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830662
Click to Show/Hide
|
||||
| Activity |
IC50 = 656770 nM
|
[64] | |||
| Compound Name |
N-(1-(2-Aminophenyl)-2,6-dioxopiperidin-3-yl)-3,4,5-trimethoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL476466; BDBM50267432
Click to Show/Hide
|
||||
| Activity |
IC50 = 659600 nM
|
[21] | |||
| Compound Name |
Chembl1830650
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2369771; BDBM50353913
Click to Show/Hide
|
||||
| Activity |
IC50 = 671560 nM
|
[64] | |||
| Compound Name |
1-(4-Phenoxyphenethyl)-3-hydroxy-1-methylurea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL200385; BDBM50175782
Click to Show/Hide
|
||||
| Activity |
IC50 = 685000 nM
|
[29] | |||
| Compound Name |
(2S)-2-Amino-N-[(2R)-2-amino-3-phenylpropyl]-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457657; BDBM50273667
Click to Show/Hide
|
||||
| Activity |
IC50 = 771900 nM
|
[45] | |||
| Compound Name |
N-[(2R)-2-Amino-3-phenylpropyl]-L-glutamamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457658; BDBM50273668
Click to Show/Hide
|
||||
| Activity |
IC50 = 802300 nM
|
[45] | |||
| Compound Name |
(3S)-N-[(2S)-1-(Hydroxyamino)-4-methyl-1-oxopentan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830649
Click to Show/Hide
|
||||
| Activity |
IC50 = 836490 nM
|
[64] | |||
| Compound Name |
(3S)-N-[(2S)-1-(Hydroxyamino)-1-oxo-3-phenylpropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1830652
Click to Show/Hide
|
||||
| Activity |
IC50 = 939570 nM
|
[64] | |||
| Compound Name |
N-[1-(4'-Cyano-4-biphenylyloxymethyl)-3-methylbutyl]formhydroxamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42862; SCHEMBL7509014; BDBM50100914; N-[1-[4-(4-cyanophenyl)phenoxy]-4-methylpentan-2-yl]-N-hydroxyformamide; N-[1-(4''-Cyano-biphenyl-4-yloxymethyl)-3-methyl-butyl]-N-hydroxy-formamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 950000 nM
|
[27] | |||
| Compound Name |
4-(Benzylamino)-2-cinnamamido-4-oxobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL607828; BDBM50304542
Click to Show/Hide
|
||||
| Activity |
IC50 = 999000 nM
|
[11] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
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| REF 2 | US patent application no. 9206139B2, Aggrecanase inhibitors | ||||
| REF 3 | Novel 5,5-disubstitutedpyrimidine-2,4,6-triones as selective MMP inhibitors. Bioorg Med Chem Lett. 2001 Apr 23;11(8):969-72. | ||||
| REF 4 | Methotrexate gamma-hydroxamate derivatives as potential dual target antitumor drugs. Bioorg Med Chem. 2007 Feb 1;15(3):1266-74. | ||||
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| REF 9 | Arylamino methylene bisphosphonate derivatives as bone seeking matrix metalloproteinase inhibitors. Bioorg Med Chem. 2013 Nov 1;21(21):6456-65. | ||||
| REF 10 | Identifying chelators for metalloprotein inhibitors using a fragment-based approach. J Med Chem. 2011 Jan 27;54(2):591-602. | ||||
| REF 11 | Design, synthesis, and preliminary studies of the activity of novel derivatives of N-cinnamoyl-L-aspartic acid as inhibitors of aminopeptidase N/CD13. Bioorg Med Chem. 2009 Oct 15;17(20):7398-404. | ||||
| REF 12 | Carbamoylphosphonates, a new class of in vivo active matrix metalloproteinase inhibitors. 1. Alkyl- and cycloalkylcarbamoylphosphonic acids. J Med Chem. 2004 May 20;47(11):2826-32. | ||||
| REF 13 | Design, combinatorial chemical synthesis and in vitro characterization of novel urea based gelatinase inhibitors. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2823-6. | ||||
| REF 14 | The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1189-93 | ||||
| REF 15 | Matrix metalloproteinase inhibitors based on the 3-mercaptopyrrolidine core. J Med Chem. 2013 Jun 13;56(11):4357-73. | ||||
| REF 16 | Selective non zinc binding inhibitors of MMP13. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4215-9. | ||||
| REF 17 | Design, synthesis, and QSAR studies of novel lysine derives as amino-peptidase N/CD13 inhibitors. Bioorg Med Chem. 2008 May 15;16(10):5473-81. | ||||
| REF 18 | Robust design of some selective matrix metalloproteinase-2 inhibitors over matrix metalloproteinase-9 through in silico/fragment-based lead identification and de novo lead modification: Syntheses and biological assays. Bioorg Med Chem. 2016 Sep 15;24(18):4291-4309. | ||||
| REF 19 | Dual carbonic anhydrase/matrix metalloproteinase inhibitors incorporating bisphosphonic acid moieties targeting bone tumors. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2617-20. | ||||
| REF 20 | Discovery of potent and selective succinyl hydroxamate inhibitors of matrix metalloprotease-3 (stromelysin-1). Bioorg Med Chem Lett. 2001 Feb 26;11(4):571-4. | ||||
| REF 21 | Novel aminopeptidase N inhibitors derived from antineoplaston AS2-5 (Part I). Bioorg Med Chem. 2009 Apr 15;17(8):3053-60. | ||||
| REF 22 | Novel aminopeptidase N (APN/CD13) inhibitors derived from chloramphenicol amine. Bioorg Med Chem. 2011 Sep 1;19(17):5190-8. | ||||
| REF 23 | Lung cancer and matrix metalloproteinases inhibitors of polyphenols from Selaginella tamariscina with suppression activity of migration. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2413-2417. | ||||
| REF 24 | Reverse hydroxamate-based selective TACE inhibitors. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2897-900. | ||||
| REF 25 | Novel matrix metalloproteinase inhibitors derived from quinoxalinone scaffold (Part I). Bioorg Med Chem. 2010 Feb 15;18(4):1516-25. | ||||
| REF 26 | Synthesis and evaluation of novel heterocyclic MMP inhibitors. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6864-70. | ||||
| REF 27 | Biaryl ether retrohydroxamates as potent, long-lived, orally bioavailable MMP inhibitors. Bioorg Med Chem Lett. 2001 Jun 18;11(12):1553-6. | ||||
| REF 28 | Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhib... J Med Chem. 2009 Oct 22;52(20):6347-61. | ||||
| REF 29 | N-Hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: mode of binding in a complex with MMP-8. Bioorg Med Chem Lett. 2006 Jan 1;16(1):20-4. | ||||
| REF 30 | Design, synthesis and anti-HIV-1 evaluation of hydrazide-based peptidomimetics as selective gelatinase inhibitors. Bioorg Med Chem. 2016 May 1;24(9):2125-36. | ||||
| REF 31 | Novel aminopeptidase N inhibitors derived from antineoplaston AS2-5 (Part II). Bioorg Med Chem. 2009 Apr 15;17(8):3061-71. | ||||
| REF 32 | Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9. Eur J Med Chem. 2012 Dec;58:368-76. | ||||
| REF 33 | Peptidyl 3-substituted 1-hydroxyureas as isosteric analogues of succinylhydroxamate MMP inhibitors. Eur J Med Chem. 2008 May;43(5):1008-14. | ||||
| REF 34 | Fragment-based discovery of indole inhibitors of matrix metalloproteinase-13. J Med Chem. 2011 Dec 8;54(23):8174-87. | ||||
| REF 35 | Novel aminopeptidase N (APN/CD13) inhibitors derived from 3-phenylalanyl-N'-substituted-2,6-piperidinedione. Bioorg Med Chem. 2010 Aug 15;18(16):5981-7. | ||||
| REF 36 | Identification of novel molecular scaffolds for the design of MMP-13 inhibitors: a first round of lead optimization. Eur J Med Chem. 2012 Jan;47(1):143-52. | ||||
| REF 37 | Orally active achiral N-hydroxyformamide inhibitors of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) for the treatment of osteoarthritis. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3301-6. | ||||
| REF 38 | Natural products as a gold mine for selective matrix metalloproteinases inhibitors. Bioorg Med Chem. 2012 Jul 1;20(13):4164-71. | ||||
| REF 39 | Carbonic anhydrase and matrix metalloproteinase inhibitors: sulfonylated amino acid hydroxamates with MMP inhibitory properties act as efficient inhibitors of CA isozymes I, II, and IV, and N-hydroxysulfonamides inhibit both these zinc enzymes. J Med Chem. 2000 Oct 5;43(20):3677-87. | ||||
| REF 40 | Design, synthesis and evaluation of novel metalloproteinase inhibitors based on L-tyrosine scaffold. Bioorg Med Chem. 2012 Oct 1;20(19):5738-44. | ||||
| REF 41 | US patent application no. 9187406B2, Curcumin analogues as zinc chelators and their uses | ||||
| REF 42 | Matrix metalloproteinase inhibitors: a structure-activity study. J Med Chem. 1998 Jan 15;41(2):199-223. | ||||
| REF 43 | Sulphonamide 1,4-dithia-7-azaspiro[4,4]nonane derivatives as gelatinase A inhibitors. Bioorg Med Chem. 2013 Dec 15;21(24):7752-62. | ||||
| REF 44 | Selective water-soluble gelatinase inhibitor prodrugs. J Med Chem. 2011 Oct 13;54(19):6676-90. | ||||
| REF 45 | Novel 3-phenylpropane-1,2-diamine derivates as inhibitors of aminopeptidase N (APN). Bioorg Med Chem. 2008 Dec 1;16(23):9984-90. | ||||
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| REF 47 | Synthesis and evaluation of novel oxazoline MMP inhibitors. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4935-9. | ||||
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