Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T99041 | Target Info | |||
| Target Name | HUMAN dipeptidyl peptidase 4 (DPP-4) | ||||
| Synonyms |
Tcell activation antigen CD26; TP103; T-cell activation antigen CD26; Dipeptidyl peptidase IV; Dipeptidyl peptidase 4 soluble form; DPP-IV; DPP IV; DPP 4; CD26; Adenosine deaminase complexing protein-2; Adenosine deaminase complexing protein 2; ADCP2; ADCP-2; ADABP
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| Gene Name | DPP4 | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 427 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Enalaprilat
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|
Approved | Compound Info | ||
| Synonyms |
EAL; Enalaprilate; Enalaprilatum; ENALAPRILAT INHIBITOR; Enalapril acid; Enalapril diacid; Enalaprilat anhydrous; Enalaprilic acid; Enalprilat hydrate; Enalprilate hydrate; Enalaprilat (USP); MK-422; Vasotec I.V.; N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline; N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline-water (1/2); (2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid; (2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid dihydrate; 1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE; 1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
BETULINIC ACID
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Phase 1 | Compound Info | ||
| Synonyms |
betulinic acid; 472-15-1; Mairin; Betulic acid; NSC 113090; CCRIS 6748; 3-Hydroxylup-20(29)-en-28-oic acid; UNII-4G6A18707N; 3beta-Hydroxy-20(29)-lupaene-28-oic acid; EINECS 207-448-8; NSC677578; als-357; NSC 677578; CHEMBL269277; CHEBI:3087; 3beta-Hydroxy-lup-20(29)-en-28-oic acid; 4G6A18707N; Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3beta)-; AK-72848; Lupatic Acid; SMR000445624
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| Activity |
IC50 = 55820 nM
|
[2] | |||
| Compound Name |
BDBM50382283
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|
Patented | Compound Info | ||
| Synonyms |
CHEMBL2022530; SCHEMBL15138748; BDBM50382283
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
BDBM50434165
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|
Patented | Compound Info | ||
| Synonyms |
CHEMBL2385271; SCHEMBL15129912; BDBM50434165
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
BDBM50434164
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|
Patented | Compound Info | ||
| Synonyms |
CHEMBL2385272; SCHEMBL15129855; BDBM50434164
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CRWCYVOHVXAEMF-LBPRGKRZSA-N
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Patented | Compound Info | ||
| Synonyms |
CHEMBL2385270; SCHEMBL15138926; CRWCYVOHVXAEMF-LBPRGKRZSA-N; BDBM50434166; (S)-N-(2-(2-Cyanopyrrolidine-1-yl)-2-oxoethyl)-6-fluoroquinoline-4-carboxamide
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Flavonoid derivative 4
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Patented | Compound Info | ||
| Synonyms |
PMID26394986-Compound-48
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| Activity |
IC50 = 130000 nM
|
[4] | |||
| Compound Name |
JTP-4819
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Discontinued in Phase 2 | Compound Info | ||
| Synonyms |
JTP-3399
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
1G244
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Investigative | Compound Info | ||
| Synonyms |
1G244; CHEMBL1814633; (2~{S})-2-azanyl-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione; GTPL8551; SCHEMBL19350285; C29H30N4O2F2; ZINC14949370; BDBM50350169; AKOS030528223; 847928-32-9; (S)-2-amino-4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-1-(isoindolin-2-yl)butane-1,4-dione; Y0432
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
P-Coumaric Acid
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Investigative | Compound Info | ||
| Synonyms |
p-coumaric acid; 4-Hydroxycinnamic acid; p-Hydroxycinnamic acid; 501-98-4; 4-Coumaric acid; trans-4-Hydroxycinnamic acid; 7400-08-0; trans-p-Coumaric acid; p-Cumaric acid; 3-(4-hydroxyphenyl)acrylic acid; Para-Coumaric acid; Hydroxycinnamic acid; p-Hydroxy-cinnamic acid; Naringeninic acid; p-Hydroxyphenylacrylic acid; (E)-p-Coumaric acid; trans-p-Coumarinic acid; 4'-hydroxycinnamic acid; (E)-3-(4-Hydroxyphenyl)acrylic acid; Cinnamic acid, p-hydroxy-; (E)-p-Hydroxycinnamic acid; trans-p-Hydroxycinnamic acid
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| Activity |
IC50 = 83180 nM
|
[2] | |||
| Compound Name |
PMID15664838C18
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|
Investigative | Compound Info | ||
| Synonyms |
GTPL6536; BDBM12195
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
ARI-3099
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Investigative | Compound Info | ||
| Synonyms |
compound 6 [PMID: 23594271]; compound 226 [PMID: 24997602]; Py(D)AlaboroPro
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| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
KAEMPFEROL
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Investigative | Compound Info | ||
| Synonyms |
kaempferol; 520-18-3; Kaempherol; Kempferol; Trifolitin; Populnetin; Robigenin; Rhamnolutein; Pelargidenolon; Rhamnolutin; Swartziol; Indigo Yellow; Kampherol; Nimbecetin; Kampferol; Campherol; Kaemferol; 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 5,7,4'-Trihydroxyflavonol; Pelargidenolon 1497; 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; C.I. 75640; CCRIS 41; NSC 407289; 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one; 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphe
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| Activity |
IC50 = 132000 nM
|
[4] | |||
| Compound Name |
Rutin
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Investigative | Compound Info | ||
| Synonyms |
RUTIN; 153-18-4; rutoside; Phytomelin; Quercetin 3-rutinoside; Birutan; Eldrin; Rutin trihydrate; Myrticolorin; Venoruton; Bioflavonoid; Paliuroside; Tanrutin; Osyritrin; Rutine; Rutozyd; 3-Rutinosyl quercetin; 3-Rhamnoglucosylquercetin; Quercetin 3-O-rutinoside; Rutosido; Rutosidum; Rutinum; Globularicitrin; Quercetin-3-rutinoside; Rutabion; Violaquercitrin; Globulariacitrin; Melin; Rutinic acid; Birutan Forte; Birutin; Quercetin rhamnoglucosine; Quercetin-3beta-rutinoside; UNII-5G06TVY3R7; Oxyritin; Rutosid; Ilixanthin; Rutinion acid
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| Activity |
IC50 = 145000 nM
|
[4] | |||
| Compound Name |
(5-(Aminomethyl)-4-(4-methoxyphenyl)-6-methylpyridin-2-yl)(4-aminopiperidin-1-yl)methanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688438; BDBM50339110
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(R)-(5-(Aminomethyl)-4-(4-methoxyphenyl)-6-methylpyridin-2-yl)(3-aminopyrrolidin-1-yl)methanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688437; BDBM50339109
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
5-(Aminomethyl)-4-(4-methoxyphenyl)-6-methyl-N-(5-methylisoxazol-3-yl)picolinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688436; SCHEMBL12807263; BDBM50339108
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(5-(Aminomethyl)-4-(4-methoxyphenyl)-6-methylpyridin-2-yl)(pyrrolidin-1-yl)methanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688433; BDBM50339105
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(3-(Aminomethyl)-6-(2,4-dichlorophenyl)-2-methylpyridin-4-yl)(morpholino)methanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688525; BDBM50339122
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(3-(Aminomethyl)-6-(4-methoxyphenyl)-2-methylpyridin-4-yl)(morpholino)methanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688528; BDBM50339125
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
5-Cyano-4-(2,4-dichlorophenyl)-N,6-dimethylpicolinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688412; SCHEMBL1677754; BDBM50339094; 5-cyano-4-(2,4-dichlorophenyl)-N,6-dimethylpyridine-2-carboxamide
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(5-(Aminomethyl)-4-(4-methoxyphenyl)-6-methylpyridin-2-yl)(morpholino)methanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688434; BDBM50339106
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
6-(Aminomethyl)-4-(4-chlorophenyl)-2-methylnicotinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688516; BDBM50339113; 6-(aminomethyl)-4-(4-chlorophenyl)-2-methylpyridine-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
3-(Aminomethyl)-N-cyclopropyl-6-(2,4-dichlorophenyl)-2-methylisonicotinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688523; BDBM50339120
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(R)-1-(2-(Quinoline-4-carboxamido)acetyl)pyrrolidin-2-ylboronic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233847; SCHEMBL15129800; BDBM50009370; [(2R)-1-[2-(quinoline-4-carbonylamino)acetyl]pyrrolidin-2-yl]boronic acid
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(3-(Aminomethyl)-6-(4-fluorophenyl)-2-methylpyridin-4-yl)(pyrrolidin-1-yl)methanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688519; BDBM50339116
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
5-Cyano-4-(2,4-dichlorophenyl)-6-methylpicolinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688411; BDBM50339093
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(R)-1-(3,5-Difluorophenoxy)-3-(1H-indol-2-yl)propan-2-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL496953; BDBM50265116
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| Activity |
IC50 = 50000 nM
|
[10] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814741
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
(2S,3R)-2-Amino-3-methyl-1-(3-methylidenepyrrolidin-1-yl)pentan-1-one;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3798975
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3-(Aminomethyl)-N-cyclopropyl-6-(4-methoxyphenyl)-2-methylisonicotinamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688526; BDBM50339123
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(2S,3S)-2-Amino-3-methyl-1-(5-nitroisoindolin-2-yl)pentan-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL510322; BDBM50243081
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|
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| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
(S)-2-Amino-6-(benzylamino)-1-(isoindolin-2-yl)hexan-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL520200; BDBM50243185
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| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
(3-(Aminomethyl)-6-(4-chlorophenyl)-2-methylpyridin-4-yl)(pyrrolidin-1-yl)methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688520; SCHEMBL12807264; BDBM50339117; [3-(aminomethyl)-6-(4-chlorophenyl)-2-methylpyridin-4-yl]-pyrrolidin-1-ylmethanone
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
1-(4-Methylquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-[2-(4-pyridylcarbonylamino)ethylamino]xanthine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616899
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| Activity |
IC50 ~ 50000 nM
|
[13] | |||
| Compound Name |
6-(Aminomethyl)-4-(4-methoxyphenyl)-2-methylnicotinamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688518; BDBM50339115
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(3-(Aminomethyl)-6-(2,4-dichlorophenyl)-2-methylpyridin-4-yl)(pyrrolidin-1-yl)methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688524; BDBM50339121
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
1-(4-Methylquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-(3-oxopiperazino)xanthine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616895
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| Activity |
IC50 ~ 50000 nM
|
[13] | |||
| Compound Name |
1-[(2S,4S)-4-[4-(Morpholin-4-ylmethyl)triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178973; BDBM50399724
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| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
6-(Aminomethyl)-4-(2-fluorophenyl)-2-methylnicotinamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688515; BDBM50339112
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
6-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methylnicotinamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688517; BDBM50339114
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-(5-fluoro-1,3-dihydroisoindol-2-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814739
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
Benzyl (S)-5-amino-6-(1-(diphenoxyphosphoryl)isoindolin-2-yl)-6-oxohexylcarbam-ate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL392162; BDBM50225432
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| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
5-(Aminomethyl)-N-(3,4-dichlorobenzyl)-4-(4-methoxyphenyl)-6-methylpicolinamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688435; BDBM50339107
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
Ethyl 1-(3-(aminomethyl)-6-(4-chlorophenyl)-2-methylisonicotinoyl)piperidine-4-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688522; BDBM50339119
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
5-(Aminomethyl)-4-(4-methoxyphenyl)-6-methyl-N-(2-piperazin-1-ylethyl)pyridine-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688514; BDBM50339111; 5-(aminomethyl)-4-(4-methoxyphenyl)-6-methyl-N-(2-(piperazin-1-yl)ethyl)picolinamide
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(3-(Aminomethyl)-6-(4-chlorophenyl)-2-methylpyridin-4-yl)(morpholino)methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688521; BDBM50339118
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
5-(Aminomethyl)-N-cyclopropyl-4-(4-methoxyphenyl)-6-methylpicolinamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688432; BDBM50339104
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
[(2S)-1-[(2S,3As,7aS)-2,3,3a,4,5,6,7,7a-octahydro-1H-indole-2-carbonyl]pyrrolidin-2-yl]-thiophen-2-ylmethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL269926; BDBM50374396
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| Activity |
IC50 = 50000 nM
|
[16] | |||
| Compound Name |
(2S)-2-Amino-4-[(3R)-4-[bis(4-fluorophenyl)methyl]-3-methylpiperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814749
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|
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
(3-(Aminomethyl)-6-(4-methoxyphenyl)-2-methylpyridin-4-yl)(pyrrolidin-1-yl)methanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1688527; BDBM50339124
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
1-Isoleucylazetidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL461496; CTK0A1560; DTXSID80442363; BDBM50243496; (2S,3S)-2-amino-1-(azetidin-1-yl)-3-methylpentan-1-one; Azetidine, 1-[(2S,3S)-2-amino-3-methyl-1-oxopentyl]-
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| Activity |
IC50 = 50400 nM
|
[17] | |||
| Compound Name |
2-Amino-1-azetidin-1-yl-3-methyl-pentan-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL346877; BDBM50135061
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|
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| Activity |
IC50 = 50400 nM
|
[18] | |||
| Compound Name |
(8S,9S)-9-Amino-4-methyl-8-(2,4,5-trifluorophenyl)-9,10-dihydro-8H-pyrano[2,3-h]chromen-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3968332; BDBM50198182
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| Activity |
IC50 = 50860 nM
|
[19] | |||
| Compound Name |
(R)-3-Amino-4-pyridin-4-yl-1-thiazolidin-3-yl-butan-1-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL183947; BDBM50151801
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[20] | |||
| Compound Name |
(S)-1-((S)-2,6-Diaminohexanoyl)piperidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461913; BDBM50243605
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[17] | |||
| Compound Name |
1-(2,6-Diamino-hexanoyl)-piperidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL145813; BDBM50135063
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[18] | |||
| Compound Name |
1-(Aminomethyl)-6,7-dimethoxy-N-propylisoquinoline-4-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL539758
Click to Show/Hide
|
||||
| Activity |
IC50 = 51400 nM
|
[21] | |||
| Compound Name |
(2S,4R)-1-((2S,3R)-2-Amino-3-methylpentanoyl)-4-azidopyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL511659; BDBM50243688
Click to Show/Hide
|
||||
| Activity |
IC50 = 52000 nM
|
[17] | |||
| Compound Name |
1-Isoleucyl-1,2,5,6-tetrahydropyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL452470; BDBM50243552; (2S,3S)-2-amino-1-(5,6-dihydropyridin-1(2H)-yl)-3-methylpentan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 52000 nM
|
[17] | |||
| Compound Name |
2-Amino-1-(3,6-dihydro-2H-pyridin-1-yl)-3-methyl-pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL444537; BDBM50135047
Click to Show/Hide
|
||||
| Activity |
IC50 = 52000 nM
|
[18] | |||
| Compound Name |
Ethyl 3-[1-(aminomethyl)-6,7-dimethoxyisoquinolin-4-yl]propanoate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288207
Click to Show/Hide
|
||||
| Activity |
IC50 = 52600 nM
|
[21] | |||
| Compound Name |
2-(Adamantan-1-ylamino)-1-piperidin-1-yl-ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL318511; BDBM50129930; ZINC13523023; 1-[N-(1-Adamantyl)glycyl]piperidine; AKOS000251239
Click to Show/Hide
|
||||
| Activity |
IC50 = 52600 nM
|
[22] | |||
| Compound Name |
(2R,3R,11Br)-9,10-dimethoxy-3-(4-methylpyridin-2-yl)-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL598754; SCHEMBL3556481; BDBM50309498
Click to Show/Hide
|
||||
| Activity |
IC50 = 53000 nM
|
[23] | |||
| Compound Name |
(2S,3S)-2-Amino-1-[(3S)-3-fluoropyrrolidin-1-yl]-3-[4-fluoro-2-(trifluoromethyl)phenyl]butan-1-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL191652
Click to Show/Hide
|
||||
| Activity |
IC50 = 54000 nM
|
[24] | |||
| Compound Name |
1-[[(S)-2-Pyrrolidinyl]carbonyl]-2-pyrrolidinylphosphonic acid diphenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1182947; BDBM50393202
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[15] | |||
| Compound Name |
(S)-2-Amino-4-(3-nitro-pyridin-2-ylamino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL316487; BDBM50146966
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[25] | |||
| Compound Name |
(2S,3R)-2-Amino-1-(4,6-dihydropyrrolo[3,4-c][1,2]oxazol-5-yl)-3-methylpentan-1-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3800380
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[6] | |||
| Compound Name |
Dihydrochelerythrine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
12,13-Dihydrochelerythrine; 1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine; (1,3)Benzodioxolo(5,6-c)phenanthridine, 12,13-dihydro-1,2-dimethoxy-12-methyl-; CHEMBL400359; SCHEMBL3864468; CTK5C8487; DTXSID70218913; BCP33364; HY-N0903; ZINC4716567; 3037AH; MFCD02183360; AKOS032948894; CS-3820; [1,3]Benzodioxolo[5,6-c]phenanthridine,12,13- dihydro-1,2-dimethoxy-12-methyl-; FT-0775799
Click to Show/Hide
|
||||
| Activity |
IC50 = 56230 nM
|
[2] | |||
| Compound Name |
2-[2,6-Bis(propan-2-yl)phenyl]-3-sulfanylidene-2,3-dihydro-1H-isoindol-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329471; PPS-33; SCHEMBL6927281; BDBM23842; 2-[2,6-di(propan-2-yl)phenyl]-3-sulfanylideneisoindol-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 57800 nM
|
[26] | |||
| Compound Name |
Chembl4205100
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50454664
Click to Show/Hide
|
||||
| Activity |
IC50 = 59900 nM
|
[27] | |||
| Compound Name |
(4-Methoxy-1-phenylcyclohexyl)methanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4553482; CHEMBL3112963; SCHEMBL14549633
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[28] | |||
| Compound Name |
4-Amino-2-(2,6-dimethylphenyl)isoindole-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315471; BDBM50075326; N-(2,6-Dimethylphenyl)-3-aminophthalimide; 4-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 60100 nM
|
[26] | |||
| Compound Name |
CID 76313540
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3086658; BDBM50005112
Click to Show/Hide
|
||||
| Activity |
Ki = 61000 nM
|
[29] | |||
| Compound Name |
(S)-2-Amino-6-(dibenzylamino)-1-(isoindolin-2-yl)hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL487871; BDBM50243186
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62500 nM
|
[12] | |||
| Compound Name |
(2S)-2-Amino-1-piperidin-1-yl-4-(piperidin-4-ylamino)butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328197; BDBM50146983; 2-(S)-Amino-1-piperidin-1-yl-4-(piperidin-4-ylamino)-butan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[25] | |||
| Compound Name |
Val-trp
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
L-Valyl-L-tryptophan; N-Valyltryptophan; L-Tryptophan, L-valyl-; H-VAL-TRP-OH; UNII-3G64B4AFQN; valyltryptophan; 3G64B4AFQN; CHEMBL91777; (S)-2-((S)-2-Amino-3-methylbutanamido)-3-(1H-indol-3-yl)propanoic acid; N-L-Valyl-L-tryptophan; L-Val-L-Trp-OH; Spectrum2_001488; Spectrum3_001812; L-Tryptophan, N-L-valyl-; BSPBio_003423; SCHEMBL150533; SPECTRUM1502210; SPBio_001475; CTK1A2687; KBio3_002926; DTXSID40947460; ZINC2047221; BDBM50038066; CCG-39170; MFCD00037947; AKOS015914032; (2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-(1H-indol-3-yl)propanoic acid; AS-57858; 587H379; N-(2-Amino-1-hydroxy-3-methylbutylidene)tryptophan; BRD-K46272620-001-02-2; Q27164569; (2S)-2-[(2S)-2-AMINO-3-METHYLBUTANAMIDO]-3-(1H-INDOL-3-YL)PROPANOIC ACID; (S)-2-((S)-2-Amino-3-methyl-butyrylamino)-3-(1H-indol-3-yl)-propionic acid; 2-((S)-2-Amino-3-methyl-butyrylamino)-3-(S)-1H-indol-3-yl-propionic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 65690 nM
|
[30] | |||
| Compound Name |
2-(2,6-Diisopropylphenyl)-5-hydroxyisoindoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5HPP-33; CHEMBL313952; 2-[2,6-di(propan-2-yl)phenyl]-5-hydroxyisoindole-1,3-dione; DSSTox_CID_26970; DSSTox_RID_82029; DSSTox_GSID_46970; SCHEMBL173289; DTXSID1046970; CTK8F1056; 2-(2,6-diisopropylphenyl)-5-hydroxy-1H-isoindole-1,3-dione; HMS3263J10; Tox21_300631; Tox21_501244; BDBM50075328; ZINC13777007; CCG-222548; LP01244; SDCCGSBI-0633813.P001; NCGC00248115-01; NCGC00248115-04; NCGC00254282-01; NCGC00261929-01; 5HPP-33, >=98% (HPLC), solid; J-001460; 2-(2,6-Diisopropyl-phenyl)-5-hydroxy-isoindole-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 65900 nM
|
[26] | |||
| Compound Name |
1-Pentanone, 2-amino-3-methyl-1-(1-piperidinyl)-, (2S,3S)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL83418; 1-(L-Ile-)Piperidine; SCHEMBL16578291; BDBM50243497; ZINC11959236; (2S,3S)-2-amino-3-methyl-1-(piperidin-1-yl)pentan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[17] | |||
| Compound Name |
3-Methyl-1-oxo-1-piperidin-1-ylpentan-2-aminium
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL93507; SCHEMBL6824150; BDBM50118936; AKOS000171918; 2-Amino-3-methyl-1-piperidin-1-yl-pentan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[18] | |||
| Compound Name |
(3R)-4-[(3S)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-methyl-1,4-diazepan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Diazepanone Analog 21; CHEMBL384382; BDBM13522; (S,R)
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[31] | |||
| Compound Name |
2-Amino-3-hydroxy-1-piperidin-1-yl-propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL146995; SCHEMBL6820648; BDBM50135069
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[18] | |||
| Compound Name |
1-((S)-2-Amino-4-benzylamino-butyryl)-piperidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329314; BDBM50146958
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[25] | |||
| Compound Name |
US8933056, N-(Benzyl)-Gly-boroPro
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL8285587; CHEMBL3686741; BDBM142098; US8933056, N-(Benzyl)- Gly-boroPro
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[32] | |||
| Compound Name |
(S)-2-Amino-4-(4-chloro-benzylamino)-1-(4-fluoro-piperidin-1-yl)-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL99506; BDBM50146974
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[25] | |||
| Compound Name |
4-Hydroxy-N-(2,6-dimethylphenyl)phthalimide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL424612; BDBM50066436; 2-(2,6-Dimethyl-phenyl)-5-hydroxy-isoindole-1,3-dione; 2-(2,6-dimethylphenyl)-5-hydroxyisoindoline-1,3-dione; 2-(2,6-dimethylphenyl)-5-hydroxy-isoindoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 74100 nM
|
[26] | |||
| Compound Name |
5-(Aminomethyl)-6-(3-methoxyphenyl)-2-phenylpyrimidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1b-meta-OMe; Aminomethylpyrimidine 1bh; CHEMBL290620; SCHEMBL3368583; BDBM11570
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[33] | |||
| Compound Name |
(2S,3S)-2-Amino-1-(5-fluoroisoindolin-2-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466590; BDBM50242854
Click to Show/Hide
|
||||
| Activity |
IC50 = 80100 nM
|
[12] | |||
| Compound Name |
2,5-Diamino-1-thiazolidin-3-yl-pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148954; BDBM50135085
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[18] | |||
| Compound Name |
3-(2-Aminoethyl)-6-chloro-2-methyl-4-phenylisoquinolin-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812729
Click to Show/Hide
|
||||
| Activity |
IC50 = 87000 nM
|
[34] | |||
| Compound Name |
Daphnoretin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Thymelol; Dephnoretin; NSC 291852; Dephnoretin;Thymelol; NSC-291852; UNII-1A7Q3KY3LH; 1A7Q3KY3LH; COUMARIN, 7-HYDROXY-6-METHOXY-3,7'-OXYDI-; CHEMBL508494; 2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy-3-((2-oxo-2H-1-benzopyran-7-yl)oxy)-; 7-hydroxy-6-methoxy-3-(2-oxochromen-7-yl)oxy-chromen-2-one; 7-hydroxy-6-methoxy-3-(2-oxochromen-7-yloxy)chromen-2-one; 7-hydroxy-6-methoxy-3-((2-oxo-2H-chromen-7-yl)oxy)-2H-chromen-2-one; SMR000156224; C19H12O7; BRN 1299325; 7-hydroxy-6-methoxy-3-[(2-oxo-2H-chromen-7-yl)oxy]-2H-chromen-2-one; 2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy-3-[(2-oxo-2H-1-benzopyran-7-yl)oxy]-; TimTec1_001767; Oprea1_038414; MLS000574856; MLS000728531; MLS001048954; SCHEMBL13784417; DTXSID00174250; 7-hydroxy-6-methoxy-3-(2-oxochromen-7-yl)oxychromen-2-one; HMS1539A07; HMS2270K03; ZINC689683; HY-N0699; TNP00178; BDBM50241949; MFCD01082318; NSC291852; s3289; AKOS002134405; MCULE-9653901495; NCGC00017271-01; NCGC00017271-02; NCGC00142383-01; ST024716; DB-050245; CS-0009716; FT-0697970; X1122; 7-hydroxy-6-methoxy-3,7''-dicoumaryl ether; C09216; Q-100250; BRD-K81282485-001-01-3; Q15410902; 2-hydroxy-6-methoxy-3-(2-oxochromen-7-yl)oxychromen-7-one; 1-benzoyl-6-{[4-(2,3-dimethylphenyl)piperazin-1-yl]carbonyl}indoline; 7-hydroxy-6-methoxy-3-[(2-oxo-2h-1-benzopyran-7-yl)oxy]-2h-1-benzopyran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 87100 nM
|
[2] | |||
| Compound Name |
Ethyl caffeate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Ethyl 3-(3,4-dihydroxyphenyl)acrylate; Ethyl 3,4-dihydroxycinnamate; ethyl trans-caffeate; Caffeic acid ethyl ester; UNII-76GBB1JU5Y; (E)-ethyl 3-(3,4-dihydroxyphenyl)acrylate; ethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; 3,4-Dihydroxycinnamic acid ethyl ester; 76GBB1JU5Y; (E)-Ethyl Dihydroxycinnamate; CHEMBL17347; MFCD00045754; Ethyl (2e)-3-(3,4-Dihydroxyphenyl)prop-2-Enoate; 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester; (E)-ethyl caffeate; ethyl 3-(3,4-dihydroxyphenyl)prop-2-enoate; 3-(3,4-Dihydroxy-phenyl)-acrylic acid ethyl ester; SCHEMBL782032; DTXSID70876375; (E)-ethyl 3,4-dihydroxycinnamate; HY-N6966; ZINC1614326; BDBM50029196; NSC619661; AKOS005167063; AKOS025310508; CCG-266637; CS-W019100; NSC-619661; AS-18100; AS-69825; Ethyl 3,4-dihydroxycinnamate, AldrichCPR; AB0022043; Ethyl 1-(3',4'-Dihydroxyphenyl)Propenate; Ethyl (E)-3-(3,4-dihydroxyphenyl)acrylate; ethyl 3-(3,4-dihydroxyphenyl)-2-propenoate; S5640; W2117; Z3811; ethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate; Ethyl 1-(3'',4''-dihydroxyphenyl)propenate; M-7861; (E)-Ethyl 3-(3,4-dihydroxyphenyl)prop-2-enoate; 102E374; Q5404446; (E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid ethyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 = 87720 nM
|
[2] | |||
| Compound Name |
4-Amino-N-(2,6-dimethylphenyl)phthalimide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Add-213063; CHEMBL283880; 5-amino-2-(2,6-dimethylphenyl)isoindole-1,3-dione; 5-amino-2-(2,6-dimethylphenyl)isoindoline-1,3-dione; SCHEMBL4151437; CTK4C9646; DTXSID20166394; 5-Amino-2-(2,6-dimethylphenyl)-1H-isoindole-1,3(2H)-dione; BDBM50066438; 5-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dione; 1H-Isoindole-1,3(2H)-dione,5-amino-2-(2,6-dimethylphenyl)-; 1H-Isoindole-1,3(2H)-dione, 5-amino-2-(2,6-dimethylphenyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 87900 nM
|
[26] | |||
| Compound Name |
3-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329634; SCHEMBL12518770; BDBM50102842
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[35] | |||
| Compound Name |
Pro-boroPro (PBP)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL151461; BDBM50075327
Click to Show/Hide
|
||||
| Activity |
IC50 = 88200 nM
|
[26] | |||
| Compound Name |
(2S)-2-Amino-1-(2-diphenoxyphosphorylpyrrolidin-1-yl)-3-methyl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL236586; Compound 10.10; BDBM98050; CTK5J7986; diphenyl[1-(l-valyl)pyrrolidin-2-yl]phosphonate
Click to Show/Hide
|
||||
| Activity |
IC50 = 89000 nM
|
[15] | |||
| Compound Name |
Allo-Ile-Isoindoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL397070; SCHEMBL14392574; BDBM50225437; ZINC28826977; NCGC00387470-01; (2S,3R)-2-amino-1-(isoindolin-2-yl)-3-methylpentan-1-one; (2S,3R)-2-amino-1-(1,3-dihydroisoindol-2-yl)-3-methylpentan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[6] | |||
| Compound Name |
2-Amino-1-(3-hydroxy-pyrrolidin-1-yl)-3-methyl-pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL147691; BDBM50135081; AKOS012239185
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[18] | |||
| Compound Name |
(2S,3S)-2-Amino-1-(3-hydroxypyrrolidin-1-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL503809; BDBM50243553; AKOS012240510
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[17] | |||
| Compound Name |
(2S,3S)-2-Amino-1-(3-chloropyrrolidin-1-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460887; BDBM50243556
Click to Show/Hide
|
||||
| Activity |
IC50 = 94000 nM
|
[17] | |||
| Compound Name |
(3R)-3-Amino-4-(2,5-difluorophenyl)-1-[2-(trifluoromethyl)-4H,5H,6H,7H-pyrido[3,4-d][1,3]thiazol-5-yl]butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
thiazolopiperidine 73; CHEMBL363375; BDBM11971
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[36] | |||
| Compound Name |
(2S,3R)-2-Amino-3-hydroxy-1-(pyrrolidin-1-yl)butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459438; SCHEMBL15924487; BDBM50243453; (2S,3R)-2-amino-3-hydroxy-1-pyrrolidin-1-ylbutan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 98000 nM
|
[17] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]isoquinoline-8-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385279; BDBM50434190
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
CID 53312239
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329699; SCHEMBL12518740; BDBM50101332
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
Isoindolin-2-yl((2S,4S)-4-(naphthalen-2-ylamino)pyrrolidin-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488493; BDBM50243245
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
2-[(5-Cyanopyridin-2-yl)amino]-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385290; BDBM50434179
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
N-(1-Napthalenecarbonyl)-Gly-boroPro
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243373; [(2R)-1-[2-(naphthalene-1-carbonylamino)acetyl]pyrrolidin-2-yl]boronic acid; GTPL9893; SCHEMBL15541697; BDBM50326373; compound 9 [PMID: 20718420]; (R)-1-(2-(1-naphthamido)acetyl)pyrrolidin-2-ylboronic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
2-[[3-Methyl-2-oxo-7-(piperidin-4-ylamino)imidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329690; BDBM50102859
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
3-Amino-6-chloro-2-methyl-4-phenylisoquinolin-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812730; BDBM50350565
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-8-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385280; SCHEMBL15129566; BDBM50434189
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
US9346814, Ref. Cmpd No 5
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3984057; BDBM233326
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]-1-(5-fluoro-1,3-dihydroisoindol-2-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814740
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(2S)-2-Amino-1-(1,3-dihydroisoindol-2-yl)-4-[4-(9H-fluorene-9-carbonyl)piperazin-1-yl]butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814751
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(2S)-2-Amino-4-[(1R,4R)-5-[bis(4-fluorophenyl)methyl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione;dihydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3215830
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(2S)-2-Amino-1-(1,3-dihydroisoindol-2-yl)-4-(4-piperidin-1-ylpiperidin-1-yl)butane-1,4-dione;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814756
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(S)-1-((2S,4R)-4-(2-(Isoindolin-2-yl)-2-oxoethyl)-5-oxopyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243403; SCHEMBL3395715; BDBM50326376
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
N-[2-[(2S,4R)-2-Cyano-4-fluoropyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233841; BDBM50009365
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385277; SCHEMBL15129564; BDBM50434159
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S)-2-Amino-4-[(2S)-2-[4-[bis(4-fluorophenyl)methyl]piperazine-1-carbonyl]pyrrolidin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814754
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
N-[2-[(2S,4S)-4-Azido-2-cyanopyrrolidin-1-yl]-2-oxoethyl]naphthalene-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022526; BDBM50382279
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-(4-fluorophenyl)-1H-imidazo[4,5-b]pyridine-7-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233573; BDBM50009354
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N-[2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233840; BDBM50009364
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
6-Chloro-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385301; SCHEMBL15138744; BDBM50434168
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S)-1-(2-Benzamidoacetyl)-N-tert-butylpyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022524; BDBM50382277
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
1-[(2S,4S)-4-(4-Cyclopropyltriazol-1-yl)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2179406; BDBM50399740
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
Benzamide, N-(2-oxo-2-(1-pyrrolidinyl)ethyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022523; BRN 5026726; N-[2-oxo-2-(pyrrolidin-1-yl)ethyl]benzamide; N-(2-OXO-2-(PYRROLIDIN-1-YL)ETHYL)BENZAMIDE; N-(2-Oxo-2-(1-pyrrolidinyl)ethyl)benzamide; 1-(2-(N-Benzoyl)aminoethyl)-2-oxopyrrolidine; N-(2-oxo-2-pyrrolidin-1-ylethyl)benzamide; SCHEMBL1442608; CTK5H7550; DTXSID10241785; ZINC1999960; BDBM50382276; AKOS005262027; MCULE-8676559311; Z31480293
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-pyridin-4-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233561; SCHEMBL15129716; BDBM50009342
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2,2-Bis(4-chlorophenyl)-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022508; BDBM50382253
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S,4S)-1-{(2S,4S)-4-[2-(5-Chloro-1,3-dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl}-4-fluoropyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243127; SCHEMBL16509426; BDBM50326391
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-N-(3-methylbutyl)quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233546; BDBM50009321
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(2S,3R)-2-Amino-1-(4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-5-yl)-3-methylpentan-1-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3800132
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
(2s)-1-({(2s,4s)-4-[2-[4-(4-Chlorophenyl)-3,6-dihydropyridin-1(2h)-yl]-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243061; SCHEMBL3399417; BDBM50326386
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-(2-methyl-4,6-dihydropyrrolo[3,4-d][1,3]thiazol-5-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3797355
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
US9346814, Cmpd No 29 Example 34
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3929674; SCHEMBL15138774; BDBM233323
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-[(2S)-2-Cyano-4-ethylpyrrolidin-1-yl]-2-oxoethyl]naphthalene-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022532; BDBM50382285
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2s)-1-[1-(4-Phenylbutanoyl)-L-Prolyl]pyrrolidine-2-Carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
KYP-2047; CHEMBL189620; EX-A2764; KYP 2047; BDBM50155838; ZINC13584669; KYP-2047, >=95% (HPLC); 4-phenylbutanoyl-l-prolyl-2(s)-cyanopyrrolidine; Q27453163; (S)-1-((4-Phenylbutanoyl)-L-prolyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
8-Bromo-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385275; SCHEMBL16267174; BDBM50434161; N-[2-[[(2S)-2alpha-Cyanopyrrolidine]-1-yl]-2-oxoethyl]-8-bromoquinoline-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S)-2-Amino-1-(1,3-dihydroisoindol-2-yl)-4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814747
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(3S)-3-Amino-N-[bis(4-fluorophenyl)methyl]-4-(1,3-dihydroisoindol-2-yl)-4-oxobutanamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814758
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-3-phenylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022513; BDBM50382267
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]isoquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385276; BDBM50434160
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
(2S)-1-[2-(4-Naphthalen-1-yltriazol-1-yl)acetyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233553; BDBM50009330
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-4-methyl-1,3-oxazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233569; SCHEMBL15129604; BDBM50009349
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Tert-butyl N-[[1-[(3R,5S)-1-(4-phenylbutanoyl)-5-(pyrrolidine-1-carbonyl)pyrrolidin-3-yl]triazol-4-yl]methyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178957; BDBM50399719
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
Benzyl (2S,4S)-4-(4-phenyltriazol-1-yl)-2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178961; BDBM50399736
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-(4-methoxyphenyl)quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385296; BDBM50434173
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
1,3-Dihydroisoindol-2-yl-[(2S,4S)-4-[(2-methoxynaphthalen-1-yl)methylamino]pyrrolidin-2-yl]methanone;dihydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3216065
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(2S,3R)-2-Amino-3-methyl-1-(2-methyl-4,6-dihydropyrrolo[3,4-d][1,3]thiazol-5-yl)pentan-1-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3797536
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
(2S)-2-Amino-5-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)pentane-1,5-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814634
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(2S)-1-({(2S,4S)-4-[2-[4-(4-Fluorophenyl)piperazin-1-yl]-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243028; SCHEMBL3393509; BDBM50326384
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[(2-chloro-6-fluorophenyl)methyl]piperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814744
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[2,2-bis(4-chlorophenyl)acetyl]piperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814752
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
4-Phenyl-1-[(2S,4S)-4-[4-(piperazin-1-ylmethyl)triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178975; BDBM50399722
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-oxo-1H-quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385295; BDBM50434174
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-6-(trifluoromethoxy)quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385302; SCHEMBL15138749; BDBM50434167
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-phenylpyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233558; SCHEMBL15129916; BDBM50009339
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(S)-N-(2-(2-Cyanopyrrolidine-1-yl)-2-oxoethyl)-3-hydroxyquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385298; SCHEMBL15129988; BDBM50434171; N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]-3-hydroxyquinoline-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-naphthalen-1-yloxyacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385285; BDBM50434184
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
(2S,3S)-2-Amino-1-(5-azidoisoindolin-2-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL487432; BDBM50243082
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-(1H-imidazol-5-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233567; SCHEMBL15129888; BDBM50009333
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-(4,6-dihydropyrrolo[3,4-c][1,2]oxazol-5-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3798277
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
1-[(2S,4S)-4-[4-(2-Chlorophenyl)triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178966; BDBM50399731
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
2-Amino-1-(2,3-dihydro-1H-isoindol-2-yl)-4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)butane-1,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
isoquinoline derivative 17; CHEMBL361107; SCHEMBL14392394; BDBM12194
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-3-methoxybenzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022515; BDBM50382269
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
N-[2-[(2S)-2-Cyano-4-methylpyrrolidin-1-yl]-2-oxoethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2021934; BDBM50382284
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S,3R)-2-Amino-1-(3-ethylpyrrolidin-1-yl)-3-methylpentan-1-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3797398
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
(2S)-1-[2-[Methyl(quinolin-4-ylmethyl)amino]acetyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233548; BDBM50009324
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
3-Imino-1,2-diphenylpropan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3310990; BDBM50099657; AKOS004906083
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
(2S,3R)-2-Amino-1-(4-fluoroisoindolin-2-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488105; BDBM50243128
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
(2S)-1-[(2S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243248
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
Benzyl (2S,4S)-4-[4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2179408; BDBM50399738
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
N-[(2R)-1-[(2S)-2-Cyanopyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233538; SCHEMBL15129756; BDBM50009313
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
US9346814, Cmpd No 27 Example 32
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3900683; BDBM233322
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
4-[4-[Bis(4-fluorophenyl)methyl]piperazin-1-yl]-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]-4-oxobutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022520; BDBM50382273
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
1-[4-[Bis(4-fluorophenyl)methyl]piperazin-1-yl]-4-(1,3-dihydroisoindol-2-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814738
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-thiophen-2-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022506; BDBM50382261
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S)-1-[(2S,4S)-4-[2-(5,7-Dihydro-4H-thieno[2,3-c]pyridin-6-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1242993; BDBM50326381
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2S,3S)-2-Amino-3-methyl-1-(4-methylisoindolin-2-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL469892; BDBM50242853
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-4-oxobutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022519; BDBM50382272
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
1-[(2S,4S)-4-[4-(Aminomethyl)triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178971
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
(2S)-1-[(2S,4S)-5-Oxo-4-[2-oxo-2-[2-(trifluoromethyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]ethyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1242994; SCHEMBL16509428; BDBM50326382
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-naphthalen-2-yloxyacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385284; BDBM50434185
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
(2s)-1-({(2s,4s)-4-[2-(1,3-Dihydro-2h-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)-4,4-difluoropyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243153; SCHEMBL3395679; BDBM50326392
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]naphthalene-1-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385289; BDBM50434180
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
(S)-N-(2-(2-Cyanopyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385281; SCHEMBL15138980; BDBM50434188; (S)-N-(2-(2-cyanopyrrolidine-1-yl)-2-oxoethyl)quinoline-4-carboxamide; N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-[(2S)-2-(2-Chloroacetyl)pyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233848; BDBM50009372
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
7-[(3R)-3-Aminopiperidin-1-yl]-1-[(2-cyanophenyl)methyl]-3-methyl-2-oxoimidazo[4,5-b]pyridine-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329700; BDBM50102843
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
(2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-[(4E,6E)-1-hydroxytetradeca-4,6-dien-8,10,12-triyn-3-yl]oxyoxane-3,4,5-triol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3343904; BDBM50035701
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[42] | |||
| Compound Name |
2-[[7-[(3S)-3-Aminopiperidin-1-yl]-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329694; BDBM50102849
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
2-(3,4-Difluorophenyl)-1,2,3,4-tetrahydroisoquinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
isoquinoline derivative 10; CHEMBL180664; BDBM12187; AKOS027557967
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
7-But-2-ynyl-8-ethoxy-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616893
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-5-methylquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233835; SCHEMBL15129783; BDBM50009360
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
4-Phenyl-1-[(2S,4S)-4-(4-phenyltriazol-1-yl)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178962; BDBM50399735
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
1-[(2S,4S)-4-[4-[(Dimethylamino)methyl]triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178972; BDBM50399725
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-N-(2-methoxyethyl)quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233545; BDBM50009320
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N-[2-[(2S,4S)-4-Azido-2-cyanopyrrolidin-1-yl]-2-oxoethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022525; BDBM50382278
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S)-1-[(3S)-3-Amino-4-(1,3-dihydroisoindol-2-yl)-4-oxobutanoyl]-N-[bis(4-fluorophenyl)methyl]pyrrolidine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814755
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[bis(4-fluorophenyl)methyl]-1,4-diazepan-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814745
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
N-(N-(Phenyl)butyryl-L-prolyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Suam-1221; Suam 1221; CHEMBL289651; SCHEMBL6285952; 1-Butanone,4-phenyl-1-[(2S)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinyl]-; CTK4A7890; DTXSID40150119; BDBM50051539; 4-phenyl-1-[(2S)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]butan-1-one; N-[N-(gamma-phenyl)butyryl-L-prolyl]pyrrolidine; (S)-4-phenyl-1-(2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl)butan-1-one; 4-Phenyl-1-[(S)-2-(pyrrolidine-1-carbonyl)-pyrrolidin-1-yl]-butan-1-one; 4-Phenyl-1-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-1-yl]-butan-1-one; Pyrrolidine, 1-(1-oxo-4-phenylbutyl)-2-(1-pyrolidinylcarbonyl)-, (S)-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
(S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SP-13786; UAMC-1110; CHEMBL3233842; SCHEMBL15138917; EX-A2803; BDBM50009366; MFCD29477499; ZB1498; ZINC169312174; CS-6200; SB19734; KS-000006B7; AS-35289; HY-100684; S0842
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CID 89705098
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233575; SCHEMBL15129785; BDBM50009357; N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]-[1,2,4]triazolo[1,5-a]pyrimidine-7-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2s)-1-({(2s,4s)-4-[2-(5-Trifluoromethyl-1,3-dihydro-2h-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1242966; SCHEMBL3395102; BDBM50326379
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(S)-3-Amino-3-phenyl-1-thiazolidin-3-yl-propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL364780; BDBM50151818
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[20] | |||
| Compound Name |
2-[4-[Bis(4-fluorophenyl)methyl]piperazin-1-yl]-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022516; BDBM50382258
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(3S)-3-Amino-N-benzhydryl-4-(1,3-dihydroisoindol-2-yl)-4-oxobutanamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814757
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(2S,4S)-1-[(2S)-2-Amino-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-4-oxobutanoyl]-4-azidopyrrolidine-2-carbonitrile;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3797441
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
1-[(2S,4S)-4-[4-(2,4-Difluorophenyl)triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178964; BDBM50399733
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
(2S)-2-Amino-1-(1,3-dihydroisoindol-2-yl)-4-[4-(3-phenylbenzoyl)piperazin-1-yl]butane-1,4-dione;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814753
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
1-[(2S,4S)-4-(4-Cyclohexyltriazol-1-yl)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2179407; BDBM50399739
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
5-Cyano-N-[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233845; BDBM50009374
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
7-But-2-ynyl-3-methyl-8-(3-oxopiperazin-1-yl)purine-2,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616915
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
Tert-butyl N-[[1-[(3S,5S)-5-[(2S)-2-cyanopyrrolidine-1-carbonyl]-1-(4-phenylbutanoyl)pyrrolidin-3-yl]triazol-4-yl]methyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178959; BDBM50399717
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
6-Chloro-3-[(dimethylamino)methyl]-2-(2-methylpropyl)-4-phenylisoquinolin-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812732; BDBM50350567
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
(2S)-1-[2-[2-Methoxyethyl(quinolin-4-ylmethyl)amino]acetyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233547; BDBM50009322
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
CID 53312243
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329697; SCHEMBL13719893; BDBM50101396
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
2-[(3S,5S)-5-[(2S)-2-Cyanopyrrolidine-1-carbonyl]-2-oxopyrrolidin-3-yl]-N-phenylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243093; SCHEMBL3395680; BDBM50326389; 2-[(3s,5s)-5-{[(2s)-2-cyanopyrrolidin-1-yl]carbonyl}-2-oxopyrrolidin-3-yl]-n-phenylacetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
Benzyl (2S,4S)-4-(4-pyridin-2-yltriazol-1-yl)-2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178968; BDBM50399729
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
2-[[7-[(3R)-3-Aminopiperidin-1-yl]-5-methoxy-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329695; BDBM50102848
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
US9346814, Ref. Cmpd No 4
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3896942; BDBM233325
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
3,7-Dimethyl-8-(3-oxopiperazin-1-yl)purine-2,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616914
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
8-Chloro-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385274; SCHEMBL15138756; BDBM50434162
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S,3S)-2-Amino-1-(4-fluoroisoindolin-2-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL469891; BDBM50242852
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-7-phenylquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233836; SCHEMBL15130008; BDBM50009332
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-4-methyl-1,3-thiazole-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233568; SCHEMBL15129841; BDBM50009348
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Tert-butyl N-[[1-[(3S,5S)-1-(4-phenylbutanoyl)-5-(pyrrolidine-1-carbonyl)pyrrolidin-3-yl]triazol-4-yl]methyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178960; BDBM50399737
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
(2S)-1-[2-[[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-methylamino]acetyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233549; BDBM50009325
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopiperidin-1-yl]-2-oxoethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022534; BDBM50382259
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
N-{2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl}benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2024672; SCHEMBL10022743; CTK3H4478; DTXSID20580319; BDBM50382254; (S)-N-(2-(2-Cyanopyrrolidin-1-yl)-2-oxoethyl)benzamide; Benzamide, N-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
2,6-Dichloro-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022511; BDBM50382265
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
N-[2-[(2S,4S)-2-Cyano-4-(trifluoromethyl)pyrrolidin-1-yl]-2-oxoethyl]naphthalene-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022533; BDBM50382255
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S,3S)-2-Amino-3-methyl-1-(5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL453199; BDBM50243083
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
CID 53312238
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329701; SCHEMBL12518737; BDBM50102841
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
(2S,3R)-2-Amino-3-methyl-1-(5-(trifluoromethyl)isoindolin-2-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488225; BDBM50243131
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
US9346814, Ref Cmpd No 10
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3934376; BDBM233329
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
5-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-1-(4-methoxyphenyl)-6-methylpyrazolo[3,4-d]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3618137; BDBM50120496
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[43] | |||
| Compound Name |
(3s,5s)-3-[2-(1,3-Dihydro-2h-isoindol-2-yl)-2-oxoethyl]-5-(1,3-thiazolidin-3-ylcarbonyl)pyrrolidin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243154; SCHEMBL3395728; BDBM50326393; (3S,5S)-3-[2-(1,3-dihydroisoindol-2-yl)-2-oxoethyl]-5-(1,3-thiazolidine-3-carbonyl)pyrrolidin-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2S)-1-[(2R)-1-(4-Phenylbutanoyl)pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2024671; BDBM50382287
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-(3-ethylpyrrolidin-1-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3797358
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
2-Amino-1-(2,3-dihydro-1H-isoindol-2-yl)-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)butane-1,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
isoquinoline derivative 16; CHEMBL179845; SCHEMBL14392412; BDBM12193
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
(2R,3R,5R)-2-(2,5-Difluorophenyl)-5-(4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-5-yl)oxan-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2425082; BDBM50440335
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[44] | |||
| Compound Name |
1-(4-Methylquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-[2-(acetylamino)ethylamino]xanthine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616898
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxo-5-(trifluoromethyl)imidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329698; SCHEMBL12518805; BDBM50101385
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
4-Phenyl-1-[(2S,4R)-4-(4-phenyltriazol-1-yl)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178956; BDBM50399720
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-4-[(2,2,2-trifluoroacetyl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233571; BDBM50009351
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[bis(4-fluorophenyl)methyl]-3-oxopiperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione;dihydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3216276
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-3-methylimidazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233564; SCHEMBL15129945; BDBM50009345
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2s)-1-({(2s,4s)-5-Oxo-4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]pyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243091; SCHEMBL3393495; BDBM50326387
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-1H-indole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385282; BDBM50434187
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-1H-indole-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385283; BDBM50434186
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2H-triazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233565; SCHEMBL15139038; BDBM50009346; (S)-N-(2-(2-cyanopyrrolidine-1-yl)-2-oxoethyl)-1H-1,2,3-triazole-5-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-5-morpholin-4-yl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329703; BDBM50102866
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
N-[2-[(2S)-2-Cyano-4-methylidenepyrrolidin-1-yl]-2-oxoethyl]naphthalene-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022531; BDBM50382257
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S,3S)-2-Amino-3-methyl-1-(5-(trifluoromethyl)isoindolin-2-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL469679; BDBM50243078
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
5-Bromo-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385300; SCHEMBL15130006; BDBM50434169
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Imigliptin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UNII-68UX3YT8DK; 68UX3YT8DK; CHEMBL3329696; SCHEMBL12517256; BDBM50102854; Q27264277
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
2-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxo-5-pyrrolidin-1-ylimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329702; BDBM50102868
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-(3,4-dimethoxyphenyl)pyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233559; SCHEMBL15129796; BDBM50009340
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Benzyl (2S,4S)-2-(pyrrolidine-1-carbonyl)-4-(4-trimethylsilyltriazol-1-yl)pyrrolidine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2179405; BDBM50399741
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
(2S)-1-[(2S,4S)-4-Azido-1-(4-phenylbutanoyl)pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178958; BDBM50399718
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
Tert-butyl 4-[[1-[(3S,5S)-1-(4-phenylbutanoyl)-5-(pyrrolidine-1-carbonyl)pyrrolidin-3-yl]triazol-4-yl]methyl]piperazine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178974; BDBM50399723
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
(2S)-N-Tert-butyl-1-[(2S,4S)-4-[2-(1,3-dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243215; BDBM50326396
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2S)-1-({(2S,4S)-5-Oxo-4-[2-oxo-2-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]ethyl]pyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243027; SCHEMBL16509425; BDBM50326383
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
US9346814, Ref. Cmpd No 3 (Example 5)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3937692; SCHEMBL16267642; BDBM233321; N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S,3S)-2-Amino-3-methyl-1-(5-methylisoindolin-2-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL469669; BDBM50242931
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
1-[(2S,4S)-4-[4-(3,4-Difluorophenyl)triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178965; BDBM50399732
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
5-Bromo-N-[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233844; SCHEMBL15129853; BDBM50009373
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(2S,3S)-2-Amino-1-(5-tert-butylisoindolin-2-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL469678; BDBM50243077
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022505; BDBM50382260
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(S)-N-(2-(2-Cyanopyrrolidin-1-yl)-2-oxoethyl)-1-naphthamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243374; SCHEMBL715747; BDBM50326374; N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]naphthalene-1-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
N-[(2S)-1-[(2S)-2-Cyanopyrrolidin-1-yl]-1-oxopropan-2-yl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233540; BDBM50009315
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
2-(4-Cyanophenyl)-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]pyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233560; SCHEMBL15129643; BDBM50009341
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
6-Chloro-3-(methylaminomethyl)-2-(2-methylpropyl)-4-phenylisoquinolin-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812731; BDBM50350566
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
Benzyl (S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(S)-benzyl 2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate; benzyl (2S)-2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate; CHEMBL1088406; SCHEMBL6384850; CTK1G8492; ZINC57064; DTXSID60350871; 7039AB; BDBM50316820; AKOS015891421; AS-71480; ST51038407; benzyl (S)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate; phenylmethyl (2S)-2-(pyrrolidinylcarbonyl)pyrrolidinecarboxylate; Benzyl(S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate; Benzyl (S)-(-)-2-(1-pyrrolidinyl carbonyl)-1-pyrrolidinecarboxylate; Benzyl (S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate, 97%; (2S)-2-[(Pyrrolidin-1-yl)carbonyl]pyrrolidine-1-carboxylic acid benzyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
7-Anilino-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233837; SCHEMBL15129788; BDBM50009361
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]pyridazine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233563; BDBM50009344
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(2S)-1-(2-Naphthalen-2-yloxyacetyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385288; BDBM50434181
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
2-[[7-(3-Aminoazetidin-1-yl)-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329640; SCHEMBL12518748; BDBM50102845
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-naphthalen-1-ylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385286; BDBM50434183
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
4-[[7-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2-oxoimidazo[4,5-b]pyridin-1-yl]methyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329635; SCHEMBL12517523; BDBM50102840
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
N'-[Bis(4-fluorophenyl)methyl]-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]butanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022518; BDBM50382271
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(S)-N-(2-(2-Cyanopyrrolidine-1-yl)-2-oxoethyl)piperidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233562; SCHEMBL15129577; BDBM50009343; N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]piperidine-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
7-But-2-ynyl-3-methyl-8-(3-oxopiperazin-1-yl)-1-(pyridin-3-ylmethyl)purine-2,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616911
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-[4-(3,4-difluorophenyl)triazol-1-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022521; BDBM50382274
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-3-hydroxy-2-methylquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385294; SCHEMBL15138746; BDBM50434175
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]pyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233554; SCHEMBL15139029; BDBM50009334
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S)-1-[(2S,4S)-4-[2-(1,3-Dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243216; BDBM50326397
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2S,3R)-2-Amino-3-methyl-1-(5-methylisoindolin-2-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL506177; BDBM50243130
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
1-[6-[(3R)-3-Aminopyrrolidin-1-yl]pyridin-3-yl]-4-phenylmethoxypyridin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011537; SCHEMBL14222785; BDBM50379784
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
Tyr-Pro-Ala
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2261077; Tyrosyl-prolyl-alanine; L-Tyrosyl-L-prolyl-L-alanine; BDBM50487906
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[46] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]naphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022514; BDBM50382268
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S)-1-({(2S,4S)-4-[2-(1,3-Dihydro-2H-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243402; SCHEMBL3393551; BDBM50326375
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-(4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-5-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3800436
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-7-methylquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233834; SCHEMBL15129765; BDBM50009359
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N'-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-N-[(4-fluorophenyl)methyl]butanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022517; BDBM50382270
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-1,2,3,4-tetrahydroacridine-9-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385297; BDBM50434172
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
(3S,5S)-3-[2-(1,3-Dihydroisoindol-2-yl)-2-oxoethyl]-5-(pyrrolidine-1-carbonyl)pyrrolidin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243183; SCHEMBL16502392; BDBM50326394
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
1-[(4-Methoxyquinazolin-2-yl)methyl]-3,7-dimethyl-8-(3-oxopiperazin-1-yl)purine-2,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616916
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
7-Bromo-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385273; SCHEMBL15129949; BDBM50434163
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-2-methylquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385293; SCHEMBL15138987; BDBM50434176
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
4-Amino-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233570; BDBM50009350
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(3S)-3-Amino-4-(1,3-dihydroisoindol-2-yl)-N-(3-hydroxy-1-adamantyl)-4-oxobutanamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814632
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
N-[2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl]-2-oxoethyl]naphthalene-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022528; BDBM50382281
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S)-2-Amino-1-(1,3-dihydroisoindol-2-yl)-5-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]pentane-1,5-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814737
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
4-Phenyl-1-[(2S,4S)-4-[4-(phenylmethoxymethyl)triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178970; BDBM50399727
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-3-methylbutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2024674; BDBM50382256
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
2-Chloro-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]pyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233555; BDBM50009335
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-1H-pyrrolo[2,3-b]pyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233572; SCHEMBL15129831; BDBM50009352
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(2S,4S)-4-(4-Chlorobenzylamino)-2-amino-1-(piperidin-1-yl)hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215244; BDBM50191170
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[47] | |||
| Compound Name |
2-[[7-But-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,6-dioxopurin-8-yl]amino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616897
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-4-(trifluoromethoxy)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022509; BDBM50382263
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
[(2R)-1-[(2S)-3-Methyl-2-(pyridine-3-carbonylamino)butanoyl]pyrrolidin-2-yl]boronic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333024; BDBM50431227
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
2-Bromo-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]pyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233556; BDBM50009336
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
4-Phenyl-1-[(2S,4S)-4-(4-pyridin-2-yltriazol-1-yl)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178969; BDBM50399728
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
(2s,4s)-1-({(2s,4s)-4-[2-(1,3-Dihydro-2h-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)-4-fluoropyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243126; SCHEMBL3393518; BDBM50326390
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
N-[1-[(2S)-2-Cyanopyrrolidine-1-carbonyl]cyclopropyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233541; BDBM50009316
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
US9346814, Cmpd No 37 Example 42
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233566; SCHEMBL15129600; BDBM233324; BDBM50009347; N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]-1H-1,2,4-triazole-5-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S)-1-[2-(4-Phenyltriazol-1-yl)acetyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233550; BDBM50009327
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(2S)-1-(2-Naphthalen-1-yloxyacetyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385287; BDBM50434182
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
2-Amino-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]pyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233557; BDBM50009337
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
2-(4-Chlorophenyl)-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022507; BDBM50382262
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
1-[(2S,4R)-4-Azido-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178955; BDBM50399721
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
Tert-butyl 4-[1-[2-[[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]amino]-2-oxoethyl]triazol-4-yl]piperazine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022522; BDBM50382275
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
6-Chloro-3-(hydroxymethyl)-2-methyl-4-phenylisoquinolin-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812727; SCHEMBL8787724; BDBM50350562; 6-chloro-1,2-dihydro-3-hydroxymethyl-2-methyl-1-oxo-4-phenylisoquinoline
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
(2S)-1-[(2S,4S)-4-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1242967; SCHEMBL3399176; BDBM50326380
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
N-[(4-Chlorophenyl)methyl]-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233544; BDBM50009319
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(2S)-1-[{(2S,4S)-5-Oxo-4-(2-oxo-2-(piperidin-1-yl)ethyl)pyrrolidine-2-yl}carbonyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243092; BDBM50326388
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2S)-1-[(2S,4S)-4-[2-(5-Fluoro-1,3-dihydroisoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1242940; SCHEMBL3399137; BDBM50326378
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
US9346814, Ref. Cmpd No 2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3913191; BDBM233320
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
5-Chloro-N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385299; SCHEMBL15129952; BDBM50434170
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S)-1-[2-[4-(4-Fluorophenyl)triazol-1-yl]acetyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233551; BDBM50009328
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(3S)-3-Amino-N-[1-[bis(4-fluorophenyl)methyl]pyrrolidin-3-yl]-4-(1,3-dihydroisoindol-2-yl)-4-oxobutanamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814759
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(S)-2-Amino-2-cyclohexyl-1-(3,4-dihydroisoquinolin-2(1H)-YL)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL361235; isoquinoline derivative 7; SCHEMBL14392751; BDBM12184; MB11304; (2S)-2-amino-2-cyclohexyl-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
N-(2-Oxo-2-pyrrolidin-1-ylethyl)quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233846; BDBM50009368
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
3,4-Dihydro-1H-isoquinolin-2-yl-[(2S)-pyrrolidin-2-yl]methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL179996; ZINC11754398
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-N-cyclopropylquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233543; BDBM50009318
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
1-[(2S,4S)-4-Azido-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178978; BDBM50399743
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
1-(2-Pyridylmethyl)-3-methyl-7-(2-butynyl)-8-(3-oxopiperazino)xanthine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616910
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-[(5E)-3-hydroxytrideca-1,5-dien-7,9,11-triyn-4-yl]oxyoxane-3,4,5-triol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3343905; BDBM50035700
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[42] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-1,7-naphthyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233833; SCHEMBL15129791; BDBM50009358
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S)-2-Amino-1-(1,3-dihydroisoindol-2-yl)-4-[4-[2,4,6-tri(propan-2-yl)phenyl]sulfonylpiperazin-1-yl]butane-1,4-dione;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1811949
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
1-[(2S,4S)-4-[4-(4-Bromophenyl)triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178967; BDBM50399730
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-N-methylquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233542; BDBM50009317
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
1-[(2s,4s)-4-[4-(4-Fluorophenyl)-1,2,3-Triazol-1-Yl]-2-Pyrrolidin-1-Ylcarbonyl-Pyrrolidin-1-Yl]-4-Phenyl-Butan-1-One
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178963; BDBM50399734; Q27466106
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
N-[2-[(2S,4R)-4-Azido-2-cyanopyrrolidin-1-yl]-2-oxoethyl]naphthalene-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022527; BDBM50382280
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S)-1-[(2S)-2-Amino-4-{4-[bis(4-fluorophenyl)methyl]piperazin-1-yl}-4-oxobutanoyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL362018; cyanopyrrolidine derivative 6; SCHEMBL14392630; BDBM12183
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2s)-1-({(2s,4s)-4-[2-[4-(Pyridine-4-yl)-piperazin-1-yl]-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1243060; SCHEMBL3398698; BDBM50326385
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
N-(4-Quinolinoyl)glycyl-(2-cyanopyrrolidine)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3920977; SCHEMBL16267187; BDBM233328; US9346814, Ref Cmpd No 9; N-[2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl]quinoline-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2S)-1-[2-[4-[3-(1,3-Dihydroisoindol-2-yl)-3-oxopropyl]triazol-1-yl]acetyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233552; BDBM50009329
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
Benzyl (2S,4S)-2-(pyrrolidine-1-carbonyl)-4-(triazol-1-yl)pyrrolidine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178979; BDBM50399742
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
2-(S)-Amino-4-(2-chloro-benzylamino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL98762; SCHEMBL7062524; BDBM50146971
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
(2S,3S)-2-Amino-1-(5-iodoisoindolin-2-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL508193; BDBM50243080
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
(2S)-2-Amino-2-phenyl-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
isoquinoline derivative 9; CHEMBL361758; BDBM12186
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
CID 89704940
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233574; SCHEMBL15129575; BDBM50009356
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-3-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2024673; BDBM50382288
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S,3R)-2-Amino-1-(5-fluoroisoindolin-2-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL502153; BDBM50243129
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
1-(4-Methoxyquinazoline-2-ylmethyl)-3-methyl-7-(2-butynyl)-8-(3-oxopiperazino)xanthine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616917
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2S)-2-Amino-4-[(3S)-4-[bis(4-fluorophenyl)methyl]-3-methylpiperazin-1-yl]-1-(1,3-dihydroisoindol-2-yl)butane-1,4-dione;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814748
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
US9346814, Ref Cmpd No 8
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3914236; BDBM233327
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(2s)-1-({(2s,4s)-4-[2-(5-Chloro-1,3-dihydro-2h-isoindol-2-yl)-2-oxoethyl]-5-oxopyrrolidin-2-yl}carbonyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1242939; SCHEMBL3395629; BDBM50326377
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
Benzyl (2S,4S)-4-azido-2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2178977; BDBM50399744
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
(2S)-2-Amino-1-(1,3-dihydroisoindol-2-yl)-4-[4-(naphthalen-2-ylmethyl)piperazin-1-yl]butane-1,4-dione;dihydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3216066
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-3-cyclopentyloxy-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022510; BDBM50382264
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
7-But-2-ynyl-3-methyl-8-(3-oxopiperazin-1-yl)-1-(pyridin-4-ylmethyl)purine-2,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616912
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[4-[[4-[(3S)-3-Amino-4-(1,3-dihydroisoindol-2-yl)-4-oxobutanoyl]piperazin-1-yl]methyl]phenyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814743; BDBM50350173
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
1-[(4-Methoxyquinazolin-2-yl)methyl]-3-methyl-7-(4-methylpent-3-enyl)-8-(3-oxopiperazin-1-yl)purine-2,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616919
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2S)-2-Amino-4-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]-1-[3-(trifluoromethyl)pyrrolidin-1-yl]butane-1,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3798691
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[6] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]-5-methoxyquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233839; SCHEMBL15129973; BDBM50009363
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
(S)-N-(2-(2-Cyanopyrrolidine-1-yl)-2-oxoethyl)-5-phenylquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233838; SCHEMBL15129619; BDBM50009362; N-[2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl]-5-phenylquinoline-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopyrrolidin-1-yl]-2-oxoethyl]isoquinoline-5-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2385278; BDBM50434191
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
(3S)-2-[(2S)-2-Amino-2-cyclohexylacetyl]-3,4-dihydro-1H-isoquinoline-3-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL361551; SCHEMBL14392398
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
N-[2-[(2S)-2-Cyanopiperidin-1-yl]-2-oxoethyl]naphthalene-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022535; BDBM50382286
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
N-[2-[(2S)-2-Cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2022529; BDBM50382282
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
(2S,3S)-2-Amino-1-(5-bromoisoindolin-2-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL469878; BDBM50243079
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
N-((R)-1-((S)-2-Cyanopyrrolidine-1-yl)-1-oxopropan-2-yl)quinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233539; SCHEMBL15129971; BDBM50009314; N-[(2R)-1-[(2S)-2-cyanopyrrolidin-1-yl]-1-oxopropan-2-yl]quinoline-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[(3R)-1-[1-[(2-Cyanophenyl)methyl]-3-methyl-2-oxoimidazo[4,5-b]pyridin-7-yl]piperidin-3-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3329693; BDBM50102850
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
7-But-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-piperidin-1-ylpurine-2,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616892; SCHEMBL15083818
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
1-(Aminomethyl)-6,7-dimethoxyisoquinoline-4-carboxylic acid;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL554957
Click to Show/Hide
|
||||
| Activity |
IC50 = 103000 nM
|
[21] | |||
| Compound Name |
1-[2-(Cyclohexyl-methyl-amino)-acetyl]-pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL318612; BDBM50129874
Click to Show/Hide
|
||||
| Activity |
IC50 = 103000 nM
|
[22] | |||
| Compound Name |
2-Amino-1-(3-azido-pyrrolidin-1-yl)-3-methyl-pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358358; BDBM50135051
Click to Show/Hide
|
||||
| Activity |
IC50 = 107000 nM
|
[18] | |||
| Compound Name |
(2S,3S)-2-Amino-1-(3-azidopyrrolidin-1-yl)-3-methylpentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460885; BDBM50243554
Click to Show/Hide
|
||||
| Activity |
IC50 = 107000 nM
|
[17] | |||
| Compound Name |
1-[2-(1-Isopropyl-2-methyl-propylamino)-acetyl]-pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL96891; BDBM50129878
Click to Show/Hide
|
||||
| Activity |
IC50 = 109000 nM
|
[22] | |||
| Compound Name |
2-Amino-3-[2-(2-cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-2-methyl-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329581; BDBM50129916
Click to Show/Hide
|
||||
| Activity |
IC50 = 109000 nM
|
[22] | |||
| Compound Name |
(2S)-1-[(2S)-2-Amino-3-(furan-3-yl)propanoyl]pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3127979; BDBM50449223
Click to Show/Hide
|
||||
| Activity |
IC50 = 113600 nM
|
[48] | |||
| Compound Name |
Ethyl 5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromene-8-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3121246
Click to Show/Hide
|
||||
| Activity |
IC50 = 113760 nM
|
[2] | |||
| Compound Name |
Ile-Isoindoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL469890; BDBM50242851; AKOS011514627; (2S,3S)-2-amino-1-(isoindolin-2-yl)-3-methylpentan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[17] | |||
| Compound Name |
[(2R)-1-[(2R)-2-Amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL305170; SCHEMBL14160935; BDBM50050517; AKOS015909815; ZINC169987523
Click to Show/Hide
|
||||
| Activity |
IC50 = 116000 nM
|
[49] | |||
| Compound Name |
(2S)-2,6-Diamino-1-(2-diphenoxyphosphorylpyrrolidin-1-yl)hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL391721; Compound 10.6; BDBM98046
Click to Show/Hide
|
||||
| Activity |
IC50 = 117000 nM
|
[15] | |||
| Compound Name |
(S)-2,5-Diamino-1-(pyrrolidin-1-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459643; BDBM50243459
Click to Show/Hide
|
||||
| Activity |
IC50 = 118000 nM
|
[17] | |||
| Compound Name |
(S)-3-Amino-4-oxo-4-(pyrrolidin-1-yl)butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL499101; BDBM50243412
Click to Show/Hide
|
||||
| Activity |
IC50 = 122000 nM
|
[17] | |||
| Compound Name |
(2S)-2-Amino-1-piperidin-1-yl-4-(pyridin-4-ylmethylamino)butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL99111; BDBM50146964; 2-(S)-Amino-1-piperidin-1-yl-4-[(pyridin-4-ylmethyl)-amino]-butan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[25] | |||
| Compound Name |
(2S,4R)-4-(4-Chlorobenzylamino)-2-amino-5-phenyl-1-(piperidin-1-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL213514; BDBM50191165
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[47] | |||
| Compound Name |
Diphenyl 1-((2S,3S)-2-amino-3-methylpentanoyl)pyrrolidin-2-ylphosphonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL427850; BDBM50225427
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[15] | |||
| Compound Name |
[(2-Cyclopentylamino-acetylamino)-phenyl-methyl]-phosphonic acid diphenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL344507; Compound 9.35; BDBM50135054
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[18] | |||
| Compound Name |
(S)-2-Amino-4-[bis-(4-chloro-benzyl)-amino]-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329966; BDBM50146982
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[25] | |||
| Compound Name |
(2S,4R)-4-(4-Chlorobenzylamino)-2-amino-5-methyl-1-(piperidin-1-yl)hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373665; BDBM50191169
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[47] | |||
| Compound Name |
N-(2-Cyclohexylidene-2-fluoroethyl)-1-methylpiperidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL176202
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[50] | |||
| Compound Name |
(2-Cyclohexylidene-2-fluoroethyl)({[3-(trifluoromethyl)phenyl]methyl})amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Fluoro-Olefin Analogue 16; CHEMBL179423; BDBM12434; 9.8h; N-(2-Cyclohexylidene-2-fluoroethyl)-N-[3-(trifluoromethyl)benzyl]amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[50] | |||
| Compound Name |
(2S,4S)-4-(4-Chlorobenzylamino)-2-amino-5-phenyl-1-(piperidin-1-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL214630; BDBM50191164
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[47] | |||
| Compound Name |
3-[((S)-3-Amino-4-oxo-4-piperidin-1-yl-butylamino)-methyl]-benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL330600; SCHEMBL6824311; BDBM50146969; 3-[[[(3S)-3-amino-4-oxo-4-piperidin-1-ylbutyl]amino]methyl]benzonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 = 132000 nM
|
[25] | |||
| Compound Name |
(S)-2,6-Diamino-1-(piperidin-1-yl)hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461506; 1-(lysyl)piperidine; 1-(L-Lysyl)piperidine; SCHEMBL6752685; BDBM50243558; (2S)-2,6-diamino-1-piperidin-1-ylhexan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 134900 nM
|
[18] | |||
| Compound Name |
[5-Amino-1-(piperidine-1-carbonyl)-pentyl]-carbamic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94955; BDBM50118941
Click to Show/Hide
|
||||
| Activity |
IC50 = 134900 nM
|
[51] | |||
| Compound Name |
(3R,4R)-3-Butyl-1-(6-methoxy-biphenyl-3-yl)-piperidin-4-ylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL234236; BDBM50209929
Click to Show/Hide
|
||||
| Activity |
IC50 = 142000 nM
|
[52] | |||
| Compound Name |
(3S)-4-[(2S)-2-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-[[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3086657; BDBM50005110
Click to Show/Hide
|
||||
| Activity |
Ki = 142000 nM
|
[29] | |||
| Compound Name |
(2S)-2-Amino-1-(2-diphenoxyphosphorylpyrrolidin-1-yl)-3-phenyl-propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL237658; Compound 10.7; BDBM98047
Click to Show/Hide
|
||||
| Activity |
IC50 = 142000 nM
|
[15] | |||
| Compound Name |
(S)-2-Amino-4-(4-chloro-benzylamino)-1-(3,6-dihydro-2H-pyridin-1-yl)-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL100370; BDBM50146968
Click to Show/Hide
|
||||
| Activity |
IC50 = 148000 nM
|
[25] | |||
| Compound Name |
Ethanone, 2-(cyclohexylamino)-1-(1-pyrrolidinyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Amide Analogue 25; cyclohexylglycine pyrrolidide; CHEMBL177746; SCHEMBL5325757; BDBM12443; 15.1a; AKOS000253189; N-Cyclohexyl-2-oxo-2-(1-pyrrolidinyl)ethaneamine; 2-(cyclohexylamino)-1-(pyrrolidin-1-yl)ethan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 148000 nM
|
[50] | |||
| Compound Name |
(S)-1-((S)-2,4-Diamino-butyryl)-piperidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL320672; SCHEMBL6824504; BDBM50146970
Click to Show/Hide
|
||||
| Activity |
IC50 = 151000 nM
|
[25] | |||
| Compound Name |
(S)-1-(2,4-Diamino-butyryl)-piperidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL146877; SCHEMBL6824505; BDBM50135078
Click to Show/Hide
|
||||
| Activity |
IC50 = 151000 nM
|
[18] | |||
| Compound Name |
6-Amino-5-propan-2-yl-2-sulfanylidene-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2234391; BDBM50486273
Click to Show/Hide
|
||||
| Activity |
Ki = 160000 nM
|
[53] | |||
| Compound Name |
(S)-2,6-Diamino-1-(isoindolin-2-yl)hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488226; SCHEMBL21746926; BDBM50243132; (2S)-2,6-diamino-1-(1,3-dihydroisoindol-2-yl)hexan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 161000 nM
|
[17] | |||
| Compound Name |
2-Amino-3-methyl-pentanoic acid ethyl-methyl-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL434886; BDBM50135084
Click to Show/Hide
|
||||
| Activity |
IC50 = 167000 nM
|
[18] | |||
| Compound Name |
(2S)-1-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2261078; BDBM50487907
Click to Show/Hide
|
||||
| Activity |
Ki = 170000 nM
|
[46] | |||
| Compound Name |
5-(Aminomethyl)-2-phenyl-6-[3-(trifluoromethyl)phenyl]pyrimidin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1b-meta-CF3; Aminomethylpyrimidine 1bn; CHEMBL289399; BDBM11576
Click to Show/Hide
|
||||
| Activity |
IC50 = 170000 nM
|
[33] | |||
| Compound Name |
1-(Aminomethyl)-6,7-dimethoxyisoquinoline-4-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL554882
Click to Show/Hide
|
||||
| Activity |
IC50 = 170000 nM
|
[21] | |||
| Compound Name |
(S)-2-Amino-1-(isoindolin-2-yl)-6-(naphthalen-2-ylamino)hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL487872; BDBM50243187
Click to Show/Hide
|
||||
| Activity |
IC50 = 178000 nM
|
[12] | |||
| Compound Name |
(2S)-2-Amino-4-(naphthalen-2-ylmethylamino)-1-piperidin-1-ylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL98860; BDBM50146991; 2-(S)-Amino-4-[(naphthalen-2-ylmethyl)-amino]-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 179000 nM
|
[25] | |||
| Compound Name |
(S)-N-((R)-2-Amino-1-cyclohexylethyl)-2-cyanopyrrolidine-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523066; BDBM50265117
Click to Show/Hide
|
||||
| Activity |
IC50 = 180000 nM
|
[10] | |||
| Compound Name |
(R)-1-(2-(2-Oxopyridin-1(2H)-yl)acetyl)pyrrolidin-2-ylboronic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL383855; BDBM50200731
Click to Show/Hide
|
||||
| Activity |
Ki = 182000 nM
|
[54] | |||
| Compound Name |
2-(S)-Amino-4-(3-chloro-benzylamino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL317949; BDBM50146961
Click to Show/Hide
|
||||
| Activity |
IC50 = 186000 nM
|
[25] | |||
| Compound Name |
2-(S)-Amino-4-phenethylamino-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL317312; BDBM50146954
Click to Show/Hide
|
||||
| Activity |
IC50 = 188000 nM
|
[25] | |||
| Compound Name |
3-Amino-4-oxo-4-pyrrolidin-1-yl-butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328795; BDBM50118948
Click to Show/Hide
|
||||
| Activity |
IC50 = 188000 nM
|
[18] | |||
| Compound Name |
(S)-3-Amino-4-oxo-4-(pyrrolidin-1-yl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL443373; BDBM50243452
Click to Show/Hide
|
||||
| Activity |
IC50 = 188000 nM
|
[17] | |||
| Compound Name |
(S)-2-Amino-3-hydroxy-1-(pyrrolidin-1-yl)propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459641; BDBM50243455; (2S)-1-Pyrrolizino-2-amino-3-hydroxy-1-propanone; (2S)-2-amino-3-hydroxy-1-pyrrolidin-1-ylpropan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 190000 nM
|
[17] | |||
| Compound Name |
[2-Bis(4-hydroxyphenoxy)phosphorylpyrrolidin-1-yl]-pyrrolidin-2-ylmethanone;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL9565
Click to Show/Hide
|
||||
| Activity |
IC50 = 190000 nM
|
[55] | |||
| Compound Name |
2-Amino-3-hydroxy-1-pyrrolidin-1-yl-propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97064; CTK8I9631; BDBM50118949
Click to Show/Hide
|
||||
| Activity |
IC50 = 190000 nM
|
[18] | |||
| Compound Name |
(2S)-2-Amino-4-[(4-phenylmethoxyphenyl)methylamino]-1-piperidin-1-ylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL99247; BDBM50146952; 2-(S)-Amino-4-(4-benzyloxy-benzylamino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 192000 nM
|
[25] | |||
| Compound Name |
(2S)-1-Piperidino-2-amino-4-[methyl(4-chlorobenzyl)amino]-1-butanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL98801; BDBM50146987; (S)-2-Amino-4-[(4-chloro-benzyl)-methyl-amino]-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 196000 nM
|
[25] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 99 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
BAICALEIN
Click to Show/Hide
|
Phase 2 | Compound Info | ||
| Synonyms |
baicalein; 491-67-8; 5,6,7-Trihydroxyflavone; 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one; Noroxylin; Biacalein; BaiKalein; Baicelein; UNII-49QAH60606; NSC661431; NSC 661431; CHEMBL8260; 5,6,7-trihydroxy-2-phenylchromen-4-one; CHEBI:2979; FXNFHKRTJBSTCS-UHFFFAOYSA-N; MFCD00017459; 4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-; 49QAH60606; 5,7-Trihydroxyflavone; 5,6,7-trihydroxy-2-phenyl-chromen-4-one; Sho-saiko-to; SMR000112462; SR-01000597499; Baicalein, 8; Baicalein,(S); 3WL; Baicalein, 14; Baicalein, 98%; AC1NQYPP; Tocris-1761
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[4] | |||
| Compound Name |
BAICALIN
Click to Show/Hide
|
Terminated | Compound Info | ||
| Synonyms |
Baicalin; 21967-41-9; Baicalein 7-O-glucuronide; 7-D-Glucuronic acid-5,6-dihydroxyflavone; CHEBI:2981; CHEMBL485818; UNII-347Q89U4M5; 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid; Baicalin hydrate; 347Q89U4M5; (2S,3S,4S,5R,6S)-6-((5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; 5,6,7-trihydroxyflavone 7-O-beta-D-glucuronide; BAICAILIN; beta-D-Glucopyranosiduronic acid, 5,6-dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl; 31564-28-0
Click to Show/Hide
|
||||
| Activity |
IC50 = 225000 nM
|
[4] | |||
| Compound Name |
3,7-dihydroxy-flavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3,7-dihydroxyflavone; 7-Hydroxyflavonol; 492-00-2; 3,7-dihydroxy-2-phenyl-4H-chromen-4-one; 5-Deoxygalangin; 4H-1-Benzopyran-4-one, 3,7-dihydroxy-2-phenyl-; UNII-O948D0K9BQ; O948D0K9BQ; CHEMBL210276; 3,7-dihydroxy-2-phenylchromen-4-one; 3,7-dihydroxy-flavone; 7,3'-dihydroxyflavonol; SR-01000314616; Resogalangin; SPBio_001803; Spectrum_001462; SpecPlus_000778; AC1NU2BD; Spectrum4_001767; Spectrum3_001623; Spectrum2_001652; Spectrum5_000353; 3,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one; Oprea1_793720; KBioSS_001942; KBioGR_002253
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[4] | |||
| Compound Name |
6-((S)-3-Amino-4-oxo-4-piperidin-1-yl-butylamino)-nicotinonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL418788; SCHEMBL6824833; BDBM50146963; 6-[[(3S)-3-amino-4-oxo-4-piperidin-1-ylbutyl]amino]pyridine-3-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 = 205000 nM
|
[25] | |||
| Compound Name |
Ethyl 1-(aminomethyl)-6-methoxyisoquinoline-4-carboxylate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL544474
Click to Show/Hide
|
||||
| Activity |
IC50 = 207000 nM
|
[21] | |||
| Compound Name |
2-Amino-3-(1H-imidazol-4-yl)-1-piperidin-1-yl-propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97180; BDBM50118935
Click to Show/Hide
|
||||
| Activity |
IC50 = 213000 nM
|
[18] | |||
| Compound Name |
2-Amino-2-cyclohexyl-1-piperidin-1-yl-ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148025; SCHEMBL6820738; BDBM50135071
Click to Show/Hide
|
||||
| Activity |
IC50 = 217000 nM
|
[18] | |||
| Compound Name |
2-Cyclohexylamino-1-piperidin-1-yl-propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL93558; SCHEMBL7064038; BDBM50118938; (2S)-2-amino-3-cyclohexyl-1-piperidin-1-ylpropan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 217000 nM
|
[51] | |||
| Compound Name |
4-Hydroxy-2-(2-methylsulfanyl-phenyl)-isoindole-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL345319; BDBM50075334; N-[2-(Methylthio)phenyl]-3-hydroxyphthalimide
Click to Show/Hide
|
||||
| Activity |
IC50 = 225700 nM
|
[26] | |||
| Compound Name |
2-Amino-1-piperidin-1-yl-pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL146190; BDBM50135060; 2-amino-1-piperidin-1-ylpentan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 229000 nM
|
[18] | |||
| Compound Name |
(2S,4R)-4-(4-Chlorobenzylamino)-2-amino-5-methyl-1-(piperidin-1-yl)heptan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL214580; BDBM50191167
Click to Show/Hide
|
||||
| Activity |
IC50 = 234000 nM
|
[47] | |||
| Compound Name |
(S)-Benzyl 5-amino-6-(isoindolin-2-yl)-6-oxohexylcarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488227; BDBM50243133
Click to Show/Hide
|
||||
| Activity |
IC50 = 245000 nM
|
[17] | |||
| Compound Name |
2-(S)-Amino-4-benzylamino-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL99263; BDBM50146975; (2S)-2-amino-4-(benzylamino)-1-piperidin-1-ylbutan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 247000 nM
|
[25] | |||
| Compound Name |
2,6-Diamino-1-piperidin-1-yl-hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97674; BDBM50118953
Click to Show/Hide
|
||||
| Activity |
IC50 = 247000 nM
|
[51] | |||
| Compound Name |
Isoindolin-2-yl((2S,4R)-4-(naphthalen-2-ylamino)pyrrolidin-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL453582; BDBM50243319
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[12] | |||
| Compound Name |
2-(S)-Amino-4-(3-methoxy-benzylamino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327499; BDBM50146953
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[25] | |||
| Compound Name |
2-Amino-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148285; ALBB-022685; BDBM50135080; 2-amino-1-piperidin-1-ylbutan-1-one; AKOS009839926; 1-oxo-1-piperidin-1-ylbutan-2-amine hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[18] | |||
| Compound Name |
Fluoro-Olefin Analogue 10
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL178975; BDBM12428; 9.8b; N-(2-Cyclohexylidene-2-fluoroethyl)-1-adamantan-amine; N-(2-cyclohexylidene-2-fluoroethyl)adamantan-1-amine
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[50] | |||
| Compound Name |
(2H-1,3-Benzodioxol-5-ylmethyl)(2-cyclopentylideneethyl)amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Olefin Analogue 24; CHEMBL177823; BDBM12442; 10.7c
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[50] | |||
| Compound Name |
2-Amino-1-piperidin-1-yl-hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL147314; BDBM50135062
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[18] | |||
| Compound Name |
(S)-2-Amino-4-phenylamino-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL98415; SCHEMBL7065542; BDBM50146978; ZINC13561249
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[25] | |||
| Compound Name |
Benzyl N-[(2S)-6-amino-1-[1-bis(4-acetamidophenoxy)phosphoryl-1,3-dihydroisoindol-2-yl]-1-oxohexan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL392163; BDBM50225424; benzyl (S)-5-amino-6-(1-(di-(4-acetamido)phenoxyphosphoryl)isoindolin-2-yl)-6-
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[15] | |||
| Compound Name |
Fluoro-Olefin Analogue 11
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL175442; BDBM12429; 9.8c; N-(2-cyclohexylidene-2-fluoroethyl)aniline
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[50] | |||
| Compound Name |
N-(1,3-Benzodioxol-5-ylmethyl)-2-pyrrolidin-1-ylethanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL175764; AKOS009057807
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[50] | |||
| Compound Name |
(2S,4R)-4-(4-Chlorobenzylamino)-2-amino-1-(piperidin-1-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215824; BDBM50191166
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[47] | |||
| Compound Name |
Fluoro-Olefin Analogue 7
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
9.7g; CHEMBL359843; BDBM12425; 1-Benzyl-N-(2-cyclopentylidene-2-fluoroethyl)-4-piperidinamine; 1-benzyl-N-(2-cyclopentylidene-2-fluoroethyl)piperidin-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[50] | |||
| Compound Name |
((2S,4S)-4-(Benzylamino)pyrrolidin-2-yl)(isoindolin-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL486049; BDBM50243242
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[12] | |||
| Compound Name |
(2H-1,3-Benzodioxol-5-ylmethyl)(2-cyclohexylidene-2-fluoroethyl)amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Fluoro-Olefin Analogue 14; CHEMBL179382; BDBM12432; 9.8f; N-(1,3-benzodioxol-5-ylmethyl)-2-cyclohexylidene-2-fluoroethanamine
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[50] | |||
| Compound Name |
Diphenyl 2-((2S,3S)-2-amino-3-methylpentanoyl)isoindolin-1-ylphosphonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399402; BDBM50225435
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[15] | |||
| Compound Name |
Fluoro-Olefin Analogue 19
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL366345; BDBM12437; 9.8k; 1-Benzyl-N-(2-cyclohexylidene-2-fluoroethyl)-4-piperidinamine; 1-benzyl-N-(2-cyclohexylidene-2-fluoroethyl)piperidin-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[50] | |||
| Compound Name |
(2-Cyclohexylidene-2-fluoroethyl)[(4-fluorophenyl)methyl]amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
9.8g; Fluoro-Olefin Analogue 15; CHEMBL361154; BDBM12433; N-(2-Cyclohexylidene-2-fluoroethyl)-N-(4-fluorobenzyl)-amine
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[50] | |||
| Compound Name |
N-[4-[(4-Acetamidophenoxy)-[2-[(2S,3R)-2-amino-3-methylpentanoyl]-1,3-dihydroisoindol-1-yl]phosphoryl]oxyphenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL238050; BDBM50225420; di-(4-acetamido)phenyl 2-((2S,3R)-2-amino-3-methylpentanoyl)isoindolin-1-ylphosphonate
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[15] | |||
| Compound Name |
(2-Cyclohexylidene-2-fluoroethyl)[(4-methoxyphenyl)methyl]amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Fluoro-Olefin Analogue 13; CHEMBL180424; BDBM12431; 9.8e; N-(2-Cyclohexylidene-2-fluoroethyl)-N-(4-methoxybenzyl)amine
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[50] | |||
| Compound Name |
1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90558; 5-amino-2-[2,6-di(propan-2-yl)phenyl]isoindole-1,3-dione; 5-amino-2-(2,6-diisopropylphenyl)isoindoline-1,3-dione; ACMC-20m3vh; SCHEMBL2818285; CTK0G8611; CLT-003; DTXSID30361232; BDBM50075333; 4-Amino-N-(2,6-diisopropylphenyl)phthalimide; 2-(2,6-diisopropylphenyl)-5-amino-1h-isoindole-1,3-dione; 5-Amino-2-(2,6-diisopropyl-phenyl)-isoindole-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 251200 nM
|
[26] | |||
| Compound Name |
Diphenyl 1-((S)-2,4-diaminobutanoyl)pyrrolidin-2-ylphosphonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL392139; BDBM50225429
Click to Show/Hide
|
||||
| Activity |
IC50 = 261000 nM
|
[15] | |||
| Compound Name |
(S)-2-Amino-4-dibenzylamino-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97970; BDBM50146967
Click to Show/Hide
|
||||
| Activity |
IC50 = 266000 nM
|
[25] | |||
| Compound Name |
1-(Aminomethyl)-6,7-dimethoxyisoquinoline-4-carbaldehyde;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL543057
Click to Show/Hide
|
||||
| Activity |
IC50 = 277000 nM
|
[21] | |||
| Compound Name |
(2S)-2-Amino-1-piperidin-1-yl-4-(thiophen-2-ylmethylamino)butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL98423; BDBM50146957; 2-(S)-Amino-1-piperidin-1-yl-4-[(thiophen-2-ylmethyl)-amino]-butan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 278000 nM
|
[25] | |||
| Compound Name |
1H-Isoindole-1,3(2H)-dione, 2-[2,6-bis(1-methylethyl)phenyl]-4-nitro-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90616; ACMC-20mjx7; SCHEMBL9812676; CTK0G1037; DTXSID30601887; BDBM50075331; 3-Nitro-N-(2,6-diisopropylphenyl)phthalimide; N-(2',6'-diisopropylphenyl)-3-nitrophthalimide; 2-(2,6-diisopropylphenyl)-4-nitroisoindoline-1,3-dione; 2-(2,6-Diisopropyl-phenyl)-4-nitro-isoindole-1,3-dione; 2-[2,6-di(propan-2-yl)phenyl]-4-nitroisoindole-1,3-dione; 2-[2,6-Di(propan-2-yl)phenyl]-4-nitro-1H-isoindole-1,3(2H)-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 283800 nM
|
[26] | |||
| Compound Name |
1H-Isoindole-1,3(2H)-dione, 2-[2,6-bis(1-methylethyl)phenyl]-5-nitro-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91130; ACMC-20m3vf; SCHEMBL2820307; CTK0G8613; DTXSID70549416; BDBM50075335; 4-Nitro-N-(2,6-diisopropylphenyl)phthalimide; N-(2,6-diisopropylphenyl)-4-nitrophthalimide; N-(2,6-diisopropylphenyl)-5-nitrophthalimide; 2-(2,6-diisopropylphenyl)-5-nitroisoindoline-1,3-dione; 2-(2,6-Diisopropyl-phenyl)-5-nitro-isoindole-1,3-dione; 2-[2,6-di(propan-2-yl)phenyl]-5-nitroisoindole-1,3-dione; 2-[2,6-Di(propan-2-yl)phenyl]-5-nitro-1H-isoindole-1,3(2H)-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 283800 nM
|
[26] | |||
| Compound Name |
(S)-2-Amino-1-(pyrrolidine-1-yl)-3-(1H-indole-3-yl)propane-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL452029; CTK1B8962; DTXSID20444841; BDBM50243409; ZINC11754554; MCULE-6977406476; (2S)-2-amino-3-(1H-indol-3-yl)-1-pyrrolidin-1-ylpropan-1-one; (S)-2-amino-3-(1H-indol-3-yl)-1-(pyrrolidin-1-yl)propan-1-one; Pyrrolidine, 1-[(2S)-2-amino-3-(1H-indol-3-yl)-1-oxopropyl]-
Click to Show/Hide
|
||||
| Activity |
IC50 = 286000 nM
|
[17] | |||
| Compound Name |
2,4-Diamino-1-thiazolidin-3-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL356207; BDBM50135042
Click to Show/Hide
|
||||
| Activity |
IC50 = 289000 nM
|
[18] | |||
| Compound Name |
(2S)-2-Amino-4-(naphthalen-1-ylmethylamino)-1-piperidin-1-ylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97884; BDBM50146960; 2-(S)-Amino-4-[(naphthalen-1-ylmethyl)-amino]-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 301000 nM
|
[25] | |||
| Compound Name |
2,6-Diamino-1-thiazolidin-3-yl-hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148955; SCHEMBL10074327; BDBM50135056
Click to Show/Hide
|
||||
| Activity |
IC50 = 318000 nM
|
[18] | |||
| Compound Name |
2-(2-Methylsulfanyl-phenyl)-4-nitro-isoindole-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL153236; BDBM50075332; N-[2-(Methylthio)phenyl]-3-nitrophthalimide
Click to Show/Hide
|
||||
| Activity |
IC50 > 318200 nM
|
[26] | |||
| Compound Name |
Ubenimex
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Bestatin; Ubenimex (Bestatin); UNII-I0J33N5627; MFCD00083262; NK-421; CHEMBL29292; 58970-76-6 (free base); I0J33N5627; Ubenimexum [Latin]; Ubenimexum; Ubenimex [INN:JAN]; Ubenimex(Bestatin); SMR000059165; EINECS 261-529-2; NK 421; NSC 265489; BRN 4704312; Ubestatin; Ubenimex, solid; NSC-265489; Ubenimex, Bestatin; Ubenimex,(S); SCHEMBL7944; (3-Amino-2-hydroxy-4-phenylbutanoyl)-L-leucine; Lopac0_000214; BSPBio_001553; KBioGR_000273; KBioSS_000273; MLS000028649; MLS001424177; MLS006010137; BCBcMAP01_000178; BDBM23971; KBio2_000273; KBio2_002841; KBio2_005409; KBio3_000545; KBio3_000546; Bio2_000273; Bio2_000753; HMS1361N15; HMS1791N15; HMS1989N15; HMS2052A03; HMS2232H13; HMS3268O06; HMS3402N15; HMS3412N16; HMS3676N16; HMS3715B20; EX-A1292; HY-B0134; KS-00000JJ0; ZINC1542895; BDBM50367209; KM0266; s1591; AKOS016339610; CCG-101071; CS-1910; DB03424; KS-5207; NC00321; QC-8204; SDCCGSBI-0050202.P003; IDI1_034023; SMP1_000030; NCGC00025323-01; NCGC00025323-02; NCGC00025323-03; NCGC00025323-04; NCGC00025323-05; NCGC00025323-06; NCGC00025323-08; NCGC00025323-14; AT-11558; BCP0726000308; AB0010690; ST50405897; AB00698345_05; 970B766; SR-01000075724-3; W-105351; BRD-K59574735-001-02-7; BRD-K59574735-001-05-0; Q10909912
Click to Show/Hide
|
||||
| Activity |
IC50 > 324300 nM
|
[26] | |||
| Compound Name |
(2S,4S)-4-(4-Chlorobenzylamino)-2-amino-1-(piperidin-1-yl)pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215299; BDBM50191168
Click to Show/Hide
|
||||
| Activity |
IC50 = 325000 nM
|
[47] | |||
| Compound Name |
2-(2,6-Diisopropyl-phenyl)-isoindole-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL89081; 2-[2,6-di(propan-2-yl)phenyl]isoindole-1,3-dione; SCHEMBL2820118; CTK1F2747; DTXSID00433915; PP-33; BDBM50075329; N-(2,6-diisopropylphenyl)-phthalimide; N-(2.6-diisopropylphenyl)-phthalimide; 2-(2,6-diisopropylphenyl)isoindoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione, 2-[2,6-bis(1-methylethyl)phenyl]-
Click to Show/Hide
|
||||
| Activity |
IC50 > 325300 nM
|
[26] | |||
| Compound Name |
(2S)-2-Amino-1-(2-diphenoxyphosphorylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL236602; Compound 10.5; BDBM98045
Click to Show/Hide
|
||||
| Activity |
IC50 = 326000 nM
|
[15] | |||
| Compound Name |
2-(2,6-Dimethylphenyl)-4-nitro-1H-isoindole-1,3(2H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL152529; 2-(2,6-Dimethyl-phenyl)-4-nitro-isoindole-1,3-dione; Oprea1_715347; MLS000702369; HMS2534I16; ZINC124891; BDBM50075337; STK248900; AKOS002960173; MCULE-3433653751; SMR000227011; ST013806; N-(2,6-Dimethylphenyl)-3-nitrophthalimide; AK-918/11238002; SR-01000214449; SR-01000214449-1; 2-(2,6-dimethylphenyl)-4-nitrobenzo[c]azolidine-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 337500 nM
|
[26] | |||
| Compound Name |
2-(2,6-Dimethylphenyl)-5-nitro-1H-isoindole-1,3(2H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-Nitro-N-(2,6-dimethylphenyl)phthalimide; CHEMBL113918; Oprea1_248930; ZINC4100043; BDBM50066444; STK268084; AKOS001599529; CCG-353901; MCULE-4049634749; N-(2,6-Dimethylphenyl)-4-nitrophthalimide; EU-0068812; ST51059083; AK-918/11423026; SR-01000405871; SR-01000405871-1; 2-(2,6-Dimethyl-phenyl)-5-nitro-isoindole-1,3-dione; 2-(2,6-dimethylphenyl)-5-nitro-isoindoline-1,3-dione; 2-(2,6-dimethylphenyl)-5-nitrobenzo[c]azoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 337500 nM
|
[26] | |||
| Compound Name |
2-Amino-3-methyl-pentanoic acid dimethylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148002; 2-amino-N,N,3-trimethylpentanamide; BDBM50135041; AKOS000195711
Click to Show/Hide
|
||||
| Activity |
IC50 = 360000 nM
|
[18] | |||
| Compound Name |
2-Amino-1-azepan-1-yl-3-methyl-pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148127; BDBM50135046; AKOS000187601
Click to Show/Hide
|
||||
| Activity |
IC50 = 374000 nM
|
[18] | |||
| Compound Name |
1-Isoleucylhexahydro-1H-azepine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL446007; BDBM50243498; ZINC13529436; (2S,3S)-2-amino-1-(azepan-1-yl)-3-methylpentan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 374000 nM
|
[17] | |||
| Compound Name |
2-(2,6-Dimethyl-phenyl)-4-hydroxy-isoindole-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL277841; BDBM50075322; N-(2,6-Dimethylphenyl)-3-hydroxyphthalimide
Click to Show/Hide
|
||||
| Activity |
IC50 > 374100 nM
|
[26] | |||
| Compound Name |
2-Amino-3-methyl-pentanoic acid methyl-propyl-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL343650; BDBM50135076
Click to Show/Hide
|
||||
| Activity |
IC50 = 377000 nM
|
[18] | |||
| Compound Name |
(S)-1-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)acetyl)pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL509777; BDBM50265118
Click to Show/Hide
|
||||
| Activity |
IC50 = 390000 nM
|
[10] | |||
| Compound Name |
2,6-Dimethylphenylphthalimide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(2,6-Dimethylphenyl)-1H-isoindole-1,3(2H)-dione; CHEMBL8916; 2-(2,6-dimethylphenyl)isoindole-1,3-dione; 2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione; 2-(2,6-dimethylphenyl)isoindoline-1,3-dione; N-(2,6-Dimethylphenyl)phthalimide; Oprea1_422137; MLS000107306; SCHEMBL10491139; DTXSID10174802; HMS2500D23; PP-11; ZINC406630; BDBM50066441; STK267942; AKOS003242716; MCULE-2967913773; SMR000111677; ST50561826; N-(2,6-dimethylphenyl)isoindoline-1,3-dione; 2-(2,6-dimethylphenyl)benzo[c]azoline-1,3-dione; AK-918/40178749; SR-01000214289; SR-01000214289-1; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dimethylphenyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 > 398000 nM
|
[26] | |||
| Compound Name |
2-(S)-Amino-4-(4-methoxy-benzylamino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL99047; BDBM50146977
Click to Show/Hide
|
||||
| Activity |
IC50 = 417000 nM
|
[25] | |||
| Compound Name |
N-((S)-3-Amino-4-oxo-4-piperidin-1-yl-butyl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL318670; SCHEMBL6824459; BDBM50146948; N-[(3S)-3-amino-4-oxo-4-piperidin-1-ylbutyl]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 418000 nM
|
[25] | |||
| Compound Name |
1-{2-[2-(5-Cyano-pyridin-2-ylamino)-ethylamino]-acetyl}-pyrrolidine-2-carboxylic acid amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL96395; CTK0I7237; DTXSID70450639; BDBM50129918; 1-[N-[2-(5-Cyano-2-pyridylamino)ethyl]glycyl]prolinamide; L-Prolinamide, N-[2-[(5-cyano-2-pyridinyl)amino]ethyl]glycyl-
Click to Show/Hide
|
||||
| Activity |
IC50 = 434000 nM
|
[22] | |||
| Compound Name |
(R)-1-(4-Oxo-4-phenylbutanoyl)pyrrolidin-2-ylboronic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL217802; BDBM50200728
Click to Show/Hide
|
||||
| Activity |
Ki = 451000 nM
|
[54] | |||
| Compound Name |
1-[2-(3-Hydroxy-adamantan-1-ylamino)-acetyl]-pyrrolidine-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94922; CHEMBL3084826; BDBM50129904; ZINC103600068; 1-[N-(3-Hydroxy-1-adamantyl)glycyl]proline
Click to Show/Hide
|
||||
| Activity |
IC50 = 477000 nM
|
[22] | |||
| Compound Name |
2-(S)-Amino-4-(cyclohexylmethyl-amino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97977; SCHEMBL8360504; BDBM50146955
Click to Show/Hide
|
||||
| Activity |
IC50 = 496000 nM
|
[25] | |||
| Compound Name |
2,6-Diamino-1-(3,6-dihydro-2H-pyridin-1-yl)-hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL359211; BDBM50135068
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[18] | |||
| Compound Name |
2,6-Diamino-1-azetidin-1-yl-hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL348246; BDBM50135052
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[18] | |||
| Compound Name |
(2S)-2,6-Diamino-1-(3-hydroxypyrrolidin-1-yl)hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461911; BDBM50243602
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[17] | |||
| Compound Name |
(S)-2-Amino-4-(4-chloro-benzylamino)-1-(2-methyl-piperidin-1-yl)-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL319520; BDBM50146979
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[25] | |||
| Compound Name |
2-(S)-Amino-4-(3-phenyl-propylamino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL430661; BDBM50146965
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[25] | |||
| Compound Name |
Fluoro-Olefin Analogue 9
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
9.8a; CHEMBL275472; BDBM12427; N-(2-cyclohexylidene-2-fluoroethyl)cyclohexanamine; N-(2-Cyclohexylidene-2-fluoroethyl)cyclohexan-amine
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[50] | |||
| Compound Name |
(S)-2-Amino-4-(4-chloro-benzylamino)-1-(3-methyl-piperidin-1-yl)-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL317950; BDBM50146950
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[25] | |||
| Compound Name |
(S)-2-Amino-4-(4-chloro-benzylamino)-1-(4-methyl-piperidin-1-yl)-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL98148; BDBM50146956
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[25] | |||
| Compound Name |
2-Amino-3-methyl-pentanoic acid diethylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL146437; BDBM50135049; AKOS000170515
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[18] | |||
| Compound Name |
((2S,4R)-4-(Dibenzylamino)pyrrolidin-2-yl)(isoindolin-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL508197; BDBM50243318
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[12] | |||
| Compound Name |
2,6-Diamino-1-(3-hydroxy-pyrrolidin-1-yl)-hexan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL144027; BDBM50135073
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[18] | |||
| Compound Name |
Benzoic acid 1-(2-amino-3-methyl-pentanoyl)-pyrrolidin-3-yl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148026; BDBM50135067
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[18] | |||
| Compound Name |
2-(S)-Amino-4-(2-methoxy-benzylamino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL98647; BDBM50146984
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[25] | |||
| Compound Name |
(2S)-2-Amino-4-[(2,4-dimethoxyphenyl)methylamino]-1-piperidin-1-ylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL99260; BDBM50146981; 2-(S)-Amino-4-(2,4-dimethoxy-benzylamino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[25] | |||
| Compound Name |
1-(3-Cyclohexyl-propionyl)-pyrrolidine-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL322904; BDBM50129869; ZINC13522821
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[22] | |||
| Compound Name |
2-[(Z)-1-Fluoro-2-(phenethylamino)ethylidene]cyclopentanecarbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Fluoro-Olefin Analogue 41; CHEMBL177265; BDBM12459; 11.7a/1; (1R,S)-(2Z)-2-{1-Fluoro-2-[(2-phenylethyl)amino]ethylidine}cyclopentanecarbonitrile; (2Z)-2-{1-fluoro-2-[(2-phenylethyl)amino]ethylidene}cyclopentane-1-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[50] | |||
| Compound Name |
Di-(4-acetamido)phenyl 2-((S)-2,6-diaminohexanoyl)isoindolin-1-ylphosphonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL440982; BDBM50225425
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[15] | |||
| Compound Name |
2,5-Diamino-1-piperidin-1-yl-pentan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329171; BDBM50118945
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[18] | |||
| Compound Name |
2,4-Diamino-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL147923; SCHEMBL1063047; BDBM50135044
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[18] | |||
| Compound Name |
Pyrrolidin-1-yl-(tetrahydro-thiophen-2-yl)-methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL343907; BDBM50135064; AKOS013916174
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[18] | |||
| Compound Name |
Pyrrolidin-2-yl-pyrrolidin-1-yl-methanethione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328655; BDBM50118954
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[51] | |||
| Compound Name |
(2E)-2-(1-Fluoro-2-{[(4-fluorophenyl)methyl]amino}ethylidene)cyclopentane-1-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Fluoro-Olefin Analogue 46; CHEMBL175966; BDBM12464; 11.7c/2; (1R,S)-(2E)-2-{1-Fluoro-2-[(4-fluorobenzyl)amino]ethylidene}cyclopentanecarbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[50] | |||
| Compound Name |
((2S,4R)-4-Aminopyrrolidin-2-yl)(isoindolin-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL452520; BDBM50243316
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[12] | |||
| Compound Name |
(S)-4-(4-Chloro-benzylamino)-2-methylamino-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL319583; BDBM50146986
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[25] | |||
| Compound Name |
(S)-2-Amino-4-(4-chloro-benzylamino)-1-(3-fluoro-piperidin-1-yl)-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL98060; BDBM50146985
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[25] | |||
| Compound Name |
(2S)-2-Amino-4-[(2-phenylmethoxyphenyl)methylamino]-1-piperidin-1-ylbutan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL418979; BDBM50146973; 2-(S)-Amino-4-(2-benzyloxy-benzylamino)-1-piperidin-1-yl-butan-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[25] | |||
| Compound Name |
Diphenyl 2-((S)-2,6-diaminohexanoyl)isoindolin-1-ylphosphonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL398373; BDBM50225440
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[15] | |||
| Compound Name |
(2S)-2-Amino-1-(2-diphenoxyphosphorylpyrrolidin-1-yl)-3-hydroxy-propan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL237673; Compound 10.8; BDBM98048
Click to Show/Hide
|
||||
| Activity |
IC50 = 503000 nM
|
[15] | |||
| Compound Name |
N-((S)-3-Amino-4-oxo-4-piperidin-1-yl-butyl)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL440325; BDBM50146988; N-[(3S)-3-amino-4-oxo-4-piperidin-1-ylbutyl]acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 518000 nM
|
[25] | |||
| Compound Name |
N-((S)-3-Amino-4-oxo-4-piperidin-1-yl-butyl)-guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL101401; BDBM50146962; 2-[(3S)-3-amino-4-oxo-4-piperidin-1-ylbutyl]guanidine
Click to Show/Hide
|
||||
| Activity |
IC50 = 545000 nM
|
[25] | |||
| Compound Name |
(R)-1-(2-Pivalamidoacetyl)pyrrolidin-2-ylboronic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL216411; BDBM50200722
Click to Show/Hide
|
||||
| Activity |
Ki = 608000 nM
|
[54] | |||
| Compound Name |
Ethyl 6,7-dimethoxy-1-(methylaminomethyl)isoquinoline-4-carboxylate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL554682
Click to Show/Hide
|
||||
| Activity |
IC50 = 731000 nM
|
[21] | |||
| Compound Name |
Ethyl 1-(2-aminoethyl)-6,7-dimethoxyisoquinoline-4-carboxylate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289580
Click to Show/Hide
|
||||
| Activity |
IC50 = 746000 nM
|
[21] | |||
| Compound Name |
1-[2-(3-Hydroxy-adamantan-1-ylamino)-acetyl]-pyrrolidine-2-carboxylic acid amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL96389; CHEMBL3084813; BDBM50129892; 1-[N-(3-Hydroxy-1-adamantyl)glycyl]prolinamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 931000 nM
|
[22] | |||
| Compound Name |
Ethyl 1-[(dimethylamino)methyl]-6,7-dimethoxyisoquinoline-4-carboxylate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL543539
Click to Show/Hide
|
||||
| Activity |
IC50 = 948000 nM
|
[21] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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