Target Regulator(s) Information (MicroRNA)

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Target General Information
The microRNAs (miRNAs) Regulating This Target
References
Target General Information  Top
Target ID T22095 Target Info
Target Name Interleukin-17 (IL17)
Synonyms Interleukin-17A; IL-17A; IL-17; Cytotoxic T-lymphocyte-associated antigen 8; Cytotoxic T lymphocyte-associated antigen 8; CTLA8; CTLA-8
Target Type Successful Target
Gene Name IL17A
Biochemical Class Cytokine: interleukin
UniProt ID
Q16552
The microRNAs (miRNAs) Regulating This Target  Top
miRNA Mature ID hsa-miR-155-3p miRNA Info
miRNA Mature AC
MIMAT0004658
Sequence cuccuacauauuagcauuaaca
miRNA Species Homo sapiens
Evidence Score (E-score) 2 +
1 qRT-PCR [1]
2 Western Blot; qRT-PCR; Immunofluorescence; Microscopy [2]
Representative Target(s) Regulated by This miRNA Cellular tumor antigen p53 (TP53) Target Info
P53_HUMAN
Erbb2 tyrosine kinase receptor (HER2) Target Info
ERBB2_HUMAN
miRNA Mature ID hsa-miR-16-1-3p miRNA Info
miRNA Mature AC
MIMAT0004489
Sequence ccaguauuaacugugcugcuga
miRNA Species Homo sapiens
Evidence Score (E-score) 1 +
1 qRT-PCR; Western Blot [3]
Representative Target(s) Regulated by This miRNA Apoptosis regulator Bcl-2 (BCL-2) Target Info
BCL2_HUMAN
G1/S-specific cyclin-D1 (CCND1) Target Info
CCND1_HUMAN
References  Top
REF 1 MicroRNA-155 regulates host immune response to postviral bacterial pneumonia via IL-23/IL-17 pathway. Am J Physiol Lung Cell Mol Physiol. 2016 Mar 1;310(5):L465-75.
REF 2 Association of microRNA-155, interleukin 17A, and proteinuria in preeclampsia. Medicine (Baltimore). 2017 May;96(18):e6509.
REF 3 MiR-15a/16 regulates the growth of myeloma cells, angiogenesis and antitumor immunity by inhibiting Bcl-2, VEGF-A and IL-17 expression in multiple myeloma. Leuk Res. 2016 Oct;49:73-9.

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