Target Regulator(s) Information (MicroRNA)

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Target General Information
The microRNAs (miRNAs) Regulating This Target
References
Target General Information  Top
Target ID T82146 Target Info
Target Name Retinoic acid receptor gamma (RARG)
Synonyms RAR-gamma; Nuclear receptor subfamily 1 group B member 3; NR1B3
Target Type Successful Target
Gene Name RARG
Biochemical Class Nuclear hormone receptor
UniProt ID
P13631
The microRNAs (miRNAs) Regulating This Target  Top
miRNA Mature ID hsa-miR-182-5p miRNA Info
miRNA Mature AC
MIMAT0000259
Sequence uuuggcaaugguagaacucacacu
miRNA Species Homo sapiens
Regulation Mechanism The overexpression of miR-182-5p by mature miRNA mimics tranfection resulted in the decreased protein level of target RARG. [1]
Evidence Score (E-score) 1 +
1 Luciferase Reporter Assay; Western Blot [1]
Representative Target(s) Regulated by This miRNA Apoptosis regulator Bcl-2 (BCL-2) Target Info
BCL2_HUMAN
Brain-derived neurotrophic factor (BDNF) Target Info
BDNF_HUMAN
miRNA Mature ID hsa-miR-34c-5p miRNA Info
miRNA Mature AC
MIMAT0000686
Sequence aggcaguguaguuagcugauugc
miRNA Species Homo sapiens
Evidence Score (E-score) 1 +
1 Luciferase Reporter Assay [2]
Representative Target(s) Regulated by This miRNA Apoptosis regulator Bcl-2 (BCL-2) Target Info
BCL2_HUMAN
Cyclin-dependent kinase 4 (CDK4) Target Info
CDK4_HUMAN
References  Top
REF 1 Alterations in microRNA expression in stress-induced cellular senescence. Mech Ageing Dev. 2009 Nov-Dec;130(11-12):731-41.
REF 2 MIR-34c regulates mouse embryonic stem cells differentiation into male germ-like cells through RARg. Cell Biochem Funct. 2012 Dec;30(8):623-32.

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