Target Interacting Proteins |
Top |
Acyltransferases |
[+] 1 Acyltransferases |
+ |
Interacting Protein Name |
E3 ubiquitin-protein ligase CHIP (STUB1) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
CHIP; HSPABP2; NY.CO.7; SCAR16; SDCCAG7; UBOX1 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[1] |
2 |
Reconstituted Complex |
[2] |
Adapter proteins |
[+] 2 Adapter proteins |
+ |
Interacting Protein Name |
Growth factor receptor-bound protein 2 (GRB2) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
SH2/SH3 adapter GRB2; Protein Ash; Growth factor receptor-bound protein 2; ASH; Adapter protein GRB2 |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[3] |
2 |
Affinity Capture-Western |
[4] |
3 |
Protein-peptide |
[5] |
4 |
Reconstituted Complex |
[6] |
Interacting Protein Name |
Erbin (ERBIN) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
ERBIN; HEL.S.78; LAP2 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[7] |
2 |
Yeast two hybrid |
[8] |
Cytokine receptors |
[+] 1 Cytokine receptors |
+ |
Interacting Target Name |
Oncostatin-M-specific receptor beta (OSMR) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
OSMRB; Oncostatin-M-specific receptor subunit beta; Interleukin-31 receptor subunit beta; IL-31R-beta; IL-31RB; IL-31R subunit beta; IL-31 receptor subunit beta |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[9] |
2 |
Co-localization |
[10] |
Ester hydrolases |
[+] 1 Ester hydrolases |
+ |
Interacting Target Name |
Protein-tyrosine phosphatase SHP-2 (PTPN11) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Tyrosine-protein phosphatase non-receptor type 11; SH-PTP3; SH-PTP2; SHPTP2; SHP-2; SHP2; PTP-2C; PTP2C; PTP-1D; Protein-tyrosine phosphatase SHP2; Protein-tyrosine phosphatase 2C; Protein-tyrosine phosphatase 1D |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[3] |
2 |
Affinity Capture-Western |
[11] |
3 |
Protein-peptide |
[5] |
4 |
Yeast two hybrid |
[12] |
Heat shock proteins |
[+] 1 Heat shock proteins |
+ |
Interacting Target Name |
Heat shock protein 90 alpha (HSP90A) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Renal carcinoma antigen NY-REN-38; LPS-associated protein 2; Lipopolysaccharide-associated protein 2; LAP-2; HSPCA; HSPC1; HSP90A; HSP86; HSP 86; Heat shock protein HSP 90-alpha; Heat shock 86 kDa |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Luminescence |
[13] |
2 |
Affinity Capture-Western |
[14] |
Kinases |
[+] 9 Kinases |
+ |
Interacting Target Name |
Epidermal growth factor receptor (EGFR) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Epidermal growth factor receptor variant III; Proto-oncogene c-ErbB-1 variant III; Receptor tyrosine-protein kinase erbB-1 variant III; EGFR variant III; ERBB variant III; ERBB1 variant III; HER1 variant III |
Evidence Score (E-score) |
3 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[15] |
2 |
Affinity Capture-Western |
[16] |
3 |
Co-localization |
[17] |
Interacting Target Name |
Tyrosine-protein kinase ABL1 (ABL) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Proto-oncogene tyrosine-protein kinase ABL1; Proto-oncogene c-Abl; p150; JTK7; C-ABL; Abl; Abelson tyrosine-protein kinase 1; Abelson murine leukemia viral oncogene homolog 1 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Protein-peptide |
[5] |
2 |
Reconstituted Complex |
[18] |
Interacting Target Name |
Proto-oncogene c-Src (SRC) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Tyrosine kinase (pp60(src)); SRC1; Src tyrosine kinase; Proto-oncogene tyrosine-protein kinase Src; pp60c-src; Pp60(src); P60-Src; C-src TK; C-Src |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[6] |
2 |
Reconstituted Complex |
[19] |
Interacting Target Name |
Erbb3 tyrosine kinase receptor (Erbb-3) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Tyrosine kinase-type cell surface receptor HER3; Receptor tyrosine-protein kinase erbB-3; Proto-oncogene-like protein c-ErbB-3; HER3; C-erbB-3 protein; C-erbB3 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[20] |
2 |
Co-localization |
[10] |
Interacting Target Name |
Focal adhesion kinase 1 (FAK) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Protein-tyrosine kinase 2; Protein phosphatase 1 regulatory subunit 71; PPP1R71; pp125FAK; p125FAK; FRNK; Focal adhesion kinase-related nonkinase; FAK1; FADK 1; FADK |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[21] |
2 |
Co-localization |
[10] |
Interacting Target Name |
Focal adhesion kinase 2 (PTK2B) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Related adhesion focal tyrosine kinase; RAFTK; PYK2; Protein-tyrosine kinase 2-beta; Proline-rich tyrosine kinase 2; FAK2; FADK 2; Cell adhesion kinase beta; Calcium-regulated non-receptor proline-rich tyrosine kinase; Calcium-dependent tyrosine kinase; CAK-beta; CAKB; CADTK |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[22] |
2 |
Co-localization |
[10] |
Interacting Target Name |
Tyrosine-protein kinase ABL2 (ABL2) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Tyrosine-protein kinase ARG; ARG; ABLL; Abelson-related gene protein; Abelson tyrosine-protein kinase 2; Abelson murine leukemia viral oncogene homolog 2 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Far Western |
[18] |
2 |
Protein-peptide |
[5] |
Interacting Protein Name |
Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
AGM7; GRB1; IMD36; p85; p85.ALPHA |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[11] |
2 |
Protein-peptide |
[5] |
Interacting Protein Name |
DNA-directed RNA polymerase I subunit RPA2 (POLR1B) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
RPA135; RPA2; Rpo1.2 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[23] |
2 |
Affinity Capture-Western |
[24] |
Transcription regulators |
[+] 1 Transcription regulators |
+ |
Interacting Target Name |
Signal transducer and activator of transcription 3 (STAT3) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Transcription factor STAT3; Stat3; Signal transducer and activator of transcription 3; APRF; Acute-phase response factor |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[19] |
2 |
Protein-peptide |
[5] |
Other proteins |
[+] 4 Other proteins |
+ |
Interacting Target Name |
Beta-catenin (CTNNB1) |
Successful Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Wnt/beta-catenin signaling pathway; PRO2286; OK/SW-cl.35; CTNNB; Catenin beta-1 |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[25] |
2 |
Co-localization |
[25] |
3 |
Far Western |
[26] |
4 |
Reconstituted Complex |
[26] |
Interacting Protein Name |
SHC-transforming protein 1 (SHC1) |
Interacting Protein |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
SHC; SHCA |
Evidence Score (E-score) |
4 Experimental Evidences |
+ |
1 |
Affinity Capture-MS |
[3] |
2 |
Affinity Capture-Western |
[4] |
3 |
Protein-peptide |
[5] |
4 |
Yeast two hybrid |
[12] |
Interacting Target Name |
Mucin-1 (MUC1) |
Clinical trial Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Tumour-associated antigen mucin 1; Tumor-associated mucin; Tumor-associated epithelial membraneantigen; Tumor-associated epithelial membrane antigen; PUM; Polymorphic epithelial mucin; PEMT; PEM; Peanut-reactive urinary mucin; Mucin-1; MUC-1; Krebs von den Lungen-6; KL-6; H23AG; Episialin; EMA; CD227 antigen; CD227; Carcinoma-associated mucin; Cancer antigen 15-3; CA 15-3; Breast carcinoma-associated antigen DF3 |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Affinity Capture-Western |
[27] |
2 |
Co-localization |
[27] |
Interacting Target Name |
Junction plakoglobin (JUP) |
Literature-reported Target |
Interacting Protein Info
|
UniProt ID |
|
Synonyms |
Plakoglobin; DP3; Desmoplakin-3; Desmoplakin III; CTNNG; Catenin gamma |
Evidence Score (E-score) |
2 Experimental Evidences |
+ |
1 |
Co-localization |
[10] |
2 |
Far Western |
[26] |