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| Target General Information |
Top |
| Target ID |
T77009 |
Target Info
|
| Target Name |
Thioredoxin reductase (PRDX5) |
| Synonyms |
Thioredoxin peroxidase PMP20; TPx type VI; SBBI10; PrxV; Prx-V; Peroxisomal antioxidant enzyme; Peroxiredoxin5, mitochondrial; Peroxiredoxin-5, mitochondrial; Peroxiredoxin V; PLP; Liver tissue 2Dpage spot 71B; Liver tissue 2D-page spot 71B; Antioxidant enzyme B166; Alu corepressor 1; AOEB166; ACR1 |
| Target Type |
Successful Target |
| Gene Name |
PRDX5 |
| Biochemical Class |
Peroxide acceptor oxidoreductase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Oxidoreductases |
[+] 1 Oxidoreductases |
+ |
| Interacting Target Name |
Superoxide dismutase Cu-Zn (SOD Cu-Zn) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Superoxide dismutase 1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase; hSod1 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Co-fractionation |
[2] |
| References |
Top |
| REF 1 |
A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-B Signaling. Cell Syst. 2017 Dec 27;5(6):564-577.e12.
|
| REF 2 |
Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
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