Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- CDK4 | 4-[(3-Hydroxy-4-pyridin-3-yl-benzylamino)-methylene]-6-iodo-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | [4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-(4-fluoro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | N-[4-(2-Methyl-imidazo[1,2-a]pyridin-3-yl)-pyrimidin-2-yl]-acetamide | Drug Info |
| CDK2 --- CDK4 | 4-[2-(4-Fluoro-phenylamino)-pyrimidin-4-yl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid amide | Drug Info |
| CDK2 --- CDK4 | N-(3-(oxazol-4-yl)phenyl)-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | (2,3-Dihydro-benzo[1,4]dioxin-6-yl)-[4-(6-methyl-pyrazolo[1,5-b]pyridazin-3-yl)-pyrimidin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | 1-{4-[4-(2-Bromo-phenylamino)-pyrimidin-2-ylamino]-phenoxy}-3-dimethylamino-propan-2-ol | Drug Info |
| CDK2 --- CDK4 | 4-(4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)benzonitrile | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-5-methyl-7-oxo-2-(4-piperazin-1-yl-phenylamino)-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester | Drug Info |
| CDK2 --- CDK4 | N-cyclopropyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | 1-(dimethylamino)-3-(4-(4-(6-morpholinopyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-ylamino)phenoxy)propan-2-ol | Drug Info |
| CDK2 --- CDK4 | CHEMBL101119 | Drug Info |
| CDK2 --- CDK4 | CHEMBL99948 | Drug Info |
| CDK2 --- CDK4 | CHEMBL322019 | Drug Info |
| CDK2 --- CDK4 | GW806290X | Drug Info |
| CDK2 --- CDK4 | 4-(4-(4-methyl-2-(methylamino)thiazol-5-yl)pyrimidin-2-ylamino)phenol | Drug Info |
| CDK2 --- CDK4 | 4-(6-isopropoxypyrazolo[1,5-b]pyridazin-3-yl)-N-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine | Drug Info |
| CDK2 --- CDK4 | (8-Isopropyl-7-methoxy-quinazolin-2-yl)-(4-piperidin-1-yl-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | [4-(2,4-Dimethyl-5-nitro-1H-pyrrol-3-yl)-pyrimidin-2-yl]-(4-fluoro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL103355 | Drug Info |
| CDK2 --- CDK4 | CHEMBL100979 | Drug Info |
| CDK2 --- CDK4 | CHEMBL101311 | Drug Info |
| CDK2 --- CDK4 | ((2-chloro-5-methylphenyl)(6-(4-(3-(dimethylamino)-2-hydroxypropoxy)phenylamino)pyrimidin-4-yl)amino)acetonitrile | Drug Info |
| CDK2 --- CDK4 | (4Z)-4-{[(3-Hydroxy-4-methoxybenzyl)amino]methylene}isoquinoline-1,3(2H,4H)-dione | Drug Info |
| CDK2 --- CDK4 | (3-Chloro-phenyl)-[4-(2,4-dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | 4-[2-(4-Hydroxy-phenylamino)-pyrimidin-4-yl]-3,5-dimethyl-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | (8-Cyclopentyl-7-methoxy-quinazolin-2-yl)-(4-piperidin-1-yl-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | N*4*-[4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-N*1*,N*1*-dimethyl-2-nitro-benzene-1,4-diamine | Drug Info |
| CDK2 --- CDK4 | GW778894X | Drug Info |
| CDK2 --- CDK4 | [4-(6-Methoxy-pyrazolo[1,5-b]pyridazin-3-yl)-pyrimidin-2-yl]-(4-nitro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | GW801372X | Drug Info |
| CDK2 --- CDK4 | CHEMBL101468 | Drug Info |
| CDK2 --- CDK4 | 3-[4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-ylamino]-benzonitrile | Drug Info |
| CDK2 --- CDK4 | 3,5-Dimethyl-4-[2-(3-nitro-phenylamino)-pyrimidin-4-yl]-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | (3-Bromo-5-trifluoromethyl-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | (4Z)-6-Fluoro-4-{[(3-hydroxy-4-methoxybenzyl)amino]methylene}-isoquinoline-1,3(2H,4H)-dione | Drug Info |
| CDK2 --- CDK4 | (4-Chloro-3-trifluoromethyl-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | [4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-[5-((R)-3-methyl-piperazin-1-ylmethyl)-pyridin-2-yl]-amine | Drug Info |
| CDK2 --- CDK4 | (4Z)-4-{[(4-Amino-3-hydroxybenzyl)amino]methylene}-6-bromoisoquinoline-1,3(2H,4H)-dione | Drug Info |
| CDK2 --- CDK4 | [4-(2-Allylamino-4-methyl-thiazol-5-yl)-pyrimidin-2-yl]-(3-nitro-phenyl)-amine | Drug Info |
| CDK2 --- CDK4 | CHEMBL457888 | Drug Info |
| CDK2 --- CDK4 | 8-Cyclopentyl-6-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one | Drug Info |
| CDK2 --- CDK4 | 4-[(3-Hydroxy-4-methoxy-benzylamino)-methylene]-6-methoxy-4H-isoquinoline-1,3-dione | Drug Info |
| CDK2 --- CDK4 | 4-(4-(2-amino-4-methylthiazol-5-yl)pyrimidin-2-ylamino)phenol | Drug Info |
| CDK2 --- CDK4 | (3,5-Dichloro-phenyl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
| CDK2 --- CDK4 | (4Z)-6-Bromo-4-({[(2-oxo-1,2-dihydropyridin-4-yl)methyl]amino}methylene) isoquinoline-1,3(2H,4H)-dione | Drug Info |
| CDK2 --- CDK4 | 3,5-Dimethyl-4-[2-(4-methyl-3-nitro-phenylamino)-pyrimidin-4-yl]-1H-pyrrole-2-carbonitrile | Drug Info |
| CDK2 --- CDK4 | CHEMBL515839 | Drug Info |
| CDK2 --- CDK4 | N,4-dimethyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)thiazol-2-amine | Drug Info |
| CDK2 --- CDK4 | (3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-(4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-yl)-amine | Drug Info |
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