| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T33754 | ||||
| Target Name | CGMP-inhibited 3',5'-cyclic phosphodiesterase | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | Amrinone | Drug Info | IC50 = 16700 nM | [552676] | |
| Enoximone | Drug Info | IC50 = 5000 nM | |||
| References | |||||
| Ref 552676 | Re-discovering PDE3 inhibitors--new opportunities for a long neglected target. Curr Top Med Chem. 2007;7(4):421-36. | ||||
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