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| Protein General Information |
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| Full Name |
Breast cancer metastasis-suppressor 1 (BRMS1)
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| UniProt ID |
BRMS1_HUMAN
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| Gene Name |
BRMS1
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| Gene ID |
25855
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| Interacting TTD Target Information |
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| Interacting Successful Target(s) |
Histone deacetylase 1 (HDAC1) |
Target Info
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PPI Info
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[1] |
| Interacting Clinical trial Target(s) |
Histone deacetylase 2 (HDAC2) |
Target Info
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PPI Info
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[2] |
| References |
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| REF 1 |
Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. Mol Cell Biol. 2006 Dec;26(23):8683-96.
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| REF 2 |
Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription. J Biol Chem. 2004 Jan 9;279(2):1562-9.
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