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| Protein General Information (TTD Target) |
Top |
| Full Name |
C-X-C chemokine receptor type 4 (CXCR4)
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Successful
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Target Info
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| UniProt ID |
CXCR4_HUMAN
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| Gene Name |
CXCR4
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| Interacting TTD Target Information |
Top |
| Interacting Clinical trial Target(s) |
Stromal cell-derived factor 1 (CXCL12) |
Target Info
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PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
E3 ubiquitin protein ligase Itchy (ITCH) |
Target Info
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PPI Info
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[2] |
| References |
Top |
| REF 1 |
High-Mobility Group Box-1 Modulates the Expression of Inflammatory and Angiogenic Signaling Pathways in Diabetic Retina. Curr Eye Res. 2015;40(11):1141-52.
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| REF 2 |
The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction. Mol Biol Cell. 2009 Mar;20(5):1324-39.
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