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Protein General Information (TTD Target) |
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Full Name |
Protein kinase C alpha (PRKCA)
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Successful
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Target Info
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UniProt ID |
KPCA_HUMAN
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Gene Name |
PRKCA
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Gene ID |
5578
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References |
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REF 1 |
Protein kinase Calpha negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor. Biochem Biophys Res Commun. 2003 Aug 8;307(4):839-46.
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REF 2 |
PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and -catenin. EMBO J. 2011 Sep 27;30(23):4838-49.
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REF 3 |
Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit. Elife. 2017 Mar 7;6. pii: e19594.
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REF 4 |
The mRNA-stabilizing factor HuR protein is targeted by -TrCP protein for degradation in response to glycolysis inhibition. J Biol Chem. 2012 Dec 21;287(52):43639-50.
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