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| Protein General Information |
Top |
| Full Name |
Mediator of DNA damage checkpoint protein 1 (MDC1)
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| UniProt ID |
MDC1_HUMAN
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| Gene Name |
MDC1
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| Gene ID |
9656
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| References |
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| REF 1 |
MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature. 2003 Feb 27;421(6926):961-6.
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| REF 2 |
Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention. EMBO J. 2004 Jul 7;23(13):2674-83.
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| REF 3 |
The direct interaction between 53BP1 and MDC1 is required for the recruitment of 53BP1 to sites of damage. J Biol Chem. 2009 Jan 2;284(1):426-35.
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