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Protein General Information |
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Full Name |
Transcriptional repressor p66-alpha (GATAD2A)
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UniProt ID |
P66A_HUMAN
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Gene Name |
GATAD2A
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Gene ID |
54815
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Interacting TTD Target Information |
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Interacting Successful Target(s) |
Histone deacetylase 1 (HDAC1) |
Target Info
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PPI Info
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[1] |
Interacting Clinical trial Target(s) |
Histone deacetylase 2 (HDAC2) |
Target Info
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PPI Info
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[2] |
Interacting Literature-reported Target(s) |
Transcription factor SOX-2 (SOX2) |
Target Info
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PPI Info
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[3] |
References |
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REF 1 |
SUMO modification enhances p66-mediated transcriptional repression of the Mi-2/NuRD complex. Mol Cell Biol. 2006 Jun;26(12):4519-28.
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REF 2 |
Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol. 2011 Mar;29(3):255-65.
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REF 3 |
Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes. Nat Genet. 2011 Jun;43(6):607-11.
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