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| Protein General Information (TTD Target) |
Top |
| Full Name |
Vitamin D3 up-regulated protein 1 (VDUP1)
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Literature-reported
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Target Info
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| UniProt ID |
TXNIP_HUMAN
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| Gene Name |
TXNIP
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| Gene ID |
10628
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| References |
Top |
| REF 1 |
VDUP1 upregulated by TGF-beta1 and 1,25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression. Oncogene. 2003 Jun 26;22(26):4035-46.
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| REF 2 |
Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP. Biochem J. 2016 Jan 15;473(2):179-87.
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| REF 3 |
Thioredoxin regulates adipogenesis through thioredoxin-interacting protein (Txnip) protein stability. J Biol Chem. 2011 Aug 19;286(33):29139-45.
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| REF 4 |
The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation. J Biol Chem. 2010 Mar 19;285(12):8869-79.
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