Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-phenylpyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(furan-2-yl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 4-(2-bromophenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | (E)-4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-(3-cinnamamidophenoxy)pyrimidine | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(4-benzyloxy-3-cyano-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | N-[4-(4-Benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-3-(2-dimethylamino-phenyl)-acrylamide | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(5-methylisoxazol-3-yloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | 4-amino-6-(4-(benzyloxy)-3-chlorophenylamino)pyrimidine-5-carbaldehyde O-methyl oxime | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-2-methoxybenzyl oxime | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-chloro-4-(4-phenylthiazol-2-ylthio)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-4-(bis-(1-methylethyl)amino)-2-butynamide | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-2-heptynamide | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-(diethylamino)-2-butynamide | Drug Info |
| EGFR3 --- HER2 | 4-(3-Dimethylamino-phenylamino)-6,7-dimethoxy-quinoline-3-carbonitrile hydrochloride | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-N-(2-(diethylamino)ethyl)-3-methyl-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide | Drug Info |
| EGFR3 --- HER2 | 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)-N-tosylacetamide | Drug Info |
| EGFR3 --- HER2 | (E)-4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-(3-p-fluorocinnamamidophenoxy)pyrimidine | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | (5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)furan-2-yl)methanol | Drug Info |
| EGFR3 --- HER2 | N1-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl)-N8-hydroxyoctanediamide | Drug Info |
| EGFR3 --- HER2 | 4-(4,4-Dihydroxy-piperidin-1-yl)-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(5-(pyridin-2-yloxy)naphthalen-2-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-chlorophenyl)acrylate | Drug Info |
| EGFR3 --- HER2 | 5-[4-(3-Chloro-4-fluoro-phenylamino)-7-methyl-6-oxo-6,7-dihydro-pyrrolo[2,3-d]pyrimidin-(5Z)-ylidenemethyl]-4-methyl-1H-pyrrole-2-carboxylic acid (2-morpholin-4-yl-ethyl)-amide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-((4-(pyrrolidin-1-ylmethyl)phenyl)ethynyl)pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 6,7-Dimethoxy-4-(3-methylsulfanyl-phenylamino)-quinoline-3-carbonitrile hydrochloride | Drug Info |
| EGFR3 --- HER2 | (R)-1-(2-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-1-yl)ethanone | Drug Info |
| EGFR3 --- HER2 | (R)-1-morpholino-2-(4-(1-(thiazol-2-ylmethyl)-1H-indazol-5-ylamino)quinazolin-5-yloxy)propan-1-one | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(1-benzyl-1H-indol-5-ylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | SID506627 | Drug Info |
| EGFR3 --- HER2 | methyl 4-amino-6-(4-(benzyloxy)-3-chlorophenylamino)pyrimidine-5-carboxylate | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-2-hexynamide | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-(trifluoromethoxy)quinolin-6-yl)-4-(dimethylamino)but-2-enamide | Drug Info |
| EGFR3 --- HER2 | 1-(5-Bromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(1-benzenesulfonyl-1H-indol-5-ylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(4-benzylamino-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | [4-(3-fluoro-benzyloxy)-3-trifluoromethyl-phenyl]-{6-[5-(1-oxo-1lambda*4*-thiomorpholin-4-ylmethyl)-furan-2-yl]-quinazolin-4-yl}-amine | Drug Info |
| EGFR3 --- HER2 | 1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(2,4-difluoro-benzyloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-bromophenyl)acrylate | Drug Info |
| EGFR3 --- HER2 | tyrphostin AG-825 | Drug Info |
| EGFR3 --- HER2 | N-(4-(4-(3-chlorobenzyloxy)-3-chlorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide | Drug Info |
| EGFR3 --- HER2 | N-[1-(3-Fluoro-benzyl)-1H-indazol-5-yl]-5-{[4-methoxy-phenylimino]-methyl}-pyrimidine-4,6-diamine | Drug Info |
| EGFR3 --- HER2 | CHEMBL429760 | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-imidazol-1-yl-phenylamino)-3-cyano-7-methoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | 4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-[3-(2-ethoxycarbonylethylamino)phenoxy]pyrimidine | Drug Info |
| EGFR3 --- HER2 | 1-(5-Chloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea | Drug Info |
| EGFR3 --- HER2 | [3-Chloro-4-(pyridin-2-ylmethoxy)-phenyl]-[7-methoxy-5-(4-methyl-piperidin-1-yloxy)-quinazolin-4-yl]-amine | Drug Info |
| EGFR3 --- HER2 | 2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-quinazolin-6-yl]-acetamide | Drug Info |
| EGFR3 --- HER2 | N4-(3-methylphenyl)-4,6-quinazolinediamine | Drug Info |
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