Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| EGFR3 --- HER2 | N-[4-(3-Chloro-4-fluoro-phenylamino)-7-(4-morpholin-4-yl-but-1-enyl)-pyrido[3,2-d]pyrimidin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | CANERTINIB DIHYDROCHLORIDE | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(naphthalen-1-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | 7-(4-(3-chloro-4-fluorophenylamino)-6-methoxyquinazolin-7-yloxy)-N-hydroxyheptanamide | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-cyclohexylmethoxy-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-5-((4-((dimethylamino)methyl)phenyl)ethynyl)-6-methylpyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-fluorobenzyloxy)-3-(trifluoromethyl)phenyl)-6-(5-((2-(1-methyl-1H-imidazol-2-ylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl 2-(methylsulfonyl)ethylcarbamate | Drug Info |
| EGFR3 --- HER2 | N1-(4-(3-chloro-4-fluorophenylamino)pyrido[3,4-d]pyrimidin-6-yl)-N4-(3-morpholinopropyl)fumaramide | Drug Info |
| EGFR3 --- HER2 | 4-(2,6-Dimethyl-piperidin-1-yl)-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-ol | Drug Info |
| EGFR3 --- HER2 | 1-(2-chloroethyl)-1-nitroso-3-{[4-(3-bromophenyl)amino]quinazolin-6-yl}urea | Drug Info |
| EGFR3 --- HER2 | SID170464951 | Drug Info |
| EGFR3 --- HER2 | 1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea | Drug Info |
| EGFR3 --- HER2 | 2-[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzylsulfanyl]-benzoic acid anion | Drug Info |
| EGFR3 --- HER2 | N-[4-(4-Benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-2-morpholin-4-ylmethyl-acrylamide | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-benzyl oxime | Drug Info |
| EGFR3 --- HER2 | {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid cis-4-amino-4-methylcyclohexyl ester | Drug Info |
| EGFR3 --- HER2 | 2-(4-Hydroxy-3-methoxy-5-phenylsulfanylmethyl-benzylidene)-malononitrile | Drug Info |
| EGFR3 --- HER2 | 4-(3-bromo-2-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | 3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-phenyl)-2-(3,4-dihydroxy-benzoyl)-acrylonitrile | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(pyridin-2-yloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(2-methoxy-benzyloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | (R)-7-(4-(1-(4-Chlorophenyl)ethylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-hydroxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(3-cyano-benzyloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | 4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-[3-(2,4,5-trifluorophenylacetamido)phenoxy]pyrimidine | Drug Info |
| EGFR3 --- HER2 | 2-(5-(4-Chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | ethyl (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-ylcarbamate | Drug Info |
| EGFR3 --- HER2 | 4-amino-6-(4-(benzyloxy)-3-chlorophenylamino)-N'-(3-morpholinopropanoyl)pyrimidine-5-carbohydrazide | Drug Info |
| EGFR3 --- HER2 | CHEMBL3302055 | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-phenoxybenzylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-(4-(morpholinomethyl)styryl)pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-methylpyrimidine-5-carbaldehyde O-3-morpholinopropyl oxime | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)-1H-indol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-methyl oxime | Drug Info |
| EGFR3 --- HER2 | 2-(5-(4-Methoxyphenyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-isobutyl oxime | Drug Info |
| EGFR3 --- HER2 | 1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-bromophenyl)amino]quinazolin-6-yl}urea | Drug Info |
| EGFR3 --- HER2 | 2-(2-(4-Methylbenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(1-benzyl-1H-indol-5-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-bromophenylamino)-3-cyanoquinolin-6-yl)but-2-enamide | Drug Info |
| EGFR3 --- HER2 | 5-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxypentanamide | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-bromophenylamino)-3-cyanoquinolin-6-yl)-4-thiomorpholinobut-2-ynamide | Drug Info |
| EGFR3 --- HER2 | (E)-4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-[3-(3,4-dimethoxycinnamamido)phenoxy]pyrimidine | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-2-propynamide | Drug Info |
| EGFR3 --- HER2 | (4-Benzyloxy-phenyl)-{6-[2-(2-methanesulfonyl-ethylamino)-thiazol-4-yl]-quinazolin-4-yl}-amine | Drug Info |
| EGFR3 --- HER2 | 4-Azetidin-1-yl-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | 2-(2-(4-Nitrobenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 7-(4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ylthio)-N-hydroxyheptanamide | Drug Info |
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