Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| EGFR3 --- HER2 | 2-(2-(3,5-Dibromo-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-((4-(morpholinomethyl)phenyl)ethynyl)pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-((5-(pyrrolidin-1-ylmethyl)furan-2-yl)ethynyl)pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid piperidin-2-ylmethyl ester | Drug Info |
| EGFR3 --- HER2 | SID124349849 | Drug Info |
| EGFR3 --- HER2 | 5-((4-aminopiperidin-1-yl)methyl)-N-(3,5-dichlorophenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| EGFR3 --- HER2 | N-(4-(benzyloxy)-3-bromophenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine | Drug Info |
| EGFR3 --- HER2 | 4-amino-6-(4-(benzyloxy)-3-chlorophenylamino)pyrimidine-5-carbonitrile | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl carbamate | Drug Info |
| EGFR3 --- HER2 | 3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-methylpyrimidin-5-yl)propiolaldehyde O-2-morpholinoethyl oxime | Drug Info |
| EGFR3 --- HER2 | 2-{2-Chloro-4-[3-cyano-6-(4-dimethylamino-but-2-enoylamino)-7-methoxy-quinolin-4-ylamino]-phenylsulfanyl}-1-methyl-3H-imidazol-1-ium | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Bromo-4-fluoro-phenylamino)-pyrido[3,2-d]pyrimidin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | 1-(2-chloroethyl)-3-{[4-(3-bromophenyl)amino]quinazolin-6-yl}urea | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-5-(5-(4-ethylpiperazin-1-yl)pent-1-ynyl)-6-methylpyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 2-[5-((E)-2-Carbamoyl-2-cyano-vinyl)-2-hydroxy-3-methoxy-benzylsulfanyl]-benzoic acid anion | Drug Info |
| EGFR3 --- HER2 | Pentanedioic acid 4-methoxy-phenyl ester 4-((E)-2-nitro-vinyl)-phenyl ester | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-5-((3-((dimethylamino)methyl)phenyl)ethynyl)-6-methylpyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | N4-(3-bromophenyl)quinazoline-4,6-diamine | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(3-fluorophenylthio)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | 8-(3-bromophenylamino)-[1,3]dioxolo[4,5-g]quinoline-7-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(3-methyl-benzyloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-3-yl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | N-[4-(4-Benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-3-(1H-imidazol-4-yl)-acrylamide | Drug Info |
| EGFR3 --- HER2 | 5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-methoxyphenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| EGFR3 --- HER2 | 1-(5-Chloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl ethyl carbonate | Drug Info |
| EGFR3 --- HER2 | 1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea | Drug Info |
| EGFR3 --- HER2 | (2-Benzyl-1H-benzoimidazol-5-yl)-(1,3,8a,9-tetraaza-fluoren-4-yl)-amine | Drug Info |
| EGFR3 --- HER2 | 4-(2-Methoxymethyl-pyrrolidin-1-yl)-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-bromophenylamino)-3-cyanoquinolin-6-yl)-4-(2-(methoxymethyl)pyrrolidin-1-yl)but-2-ynamide | Drug Info |
| EGFR3 --- HER2 | 4-(3-acetylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | {4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid 2-(piperazin-1-yl)ethyl ester | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(1-(3-fluorophenylsulfonyl)-1H-indazol-5-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | N-[4-(4-Benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-2-dimethylaminomethyl-acrylamide | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Chloro-4-fluoro-phenylamino)-quinazolin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | 4-(3-bromophenylamino)-6,7-dihydroxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-methylpyrimidin-5-yl)-2-fluoro-N-(2-(pyrrolidin-1-yl)ethyl)acrylamide | Drug Info |
| EGFR3 --- HER2 | N-(4-(o-tolylamino)quinazolin-6-yl)acrylamide | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(6-fluoroquinolin-4-yloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | CHEMBL258282 | Drug Info |
| EGFR3 --- HER2 | SID85267487 | Drug Info |
| EGFR3 --- HER2 | N4-(3-bromophenyl)-N6-methylquinazoline-4,6-diamine | Drug Info |
| EGFR3 --- HER2 | 4-(3-hydroxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | CHEMBL271705 | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-methylphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl pyrrolidine-1-carboxylate | Drug Info |
| EGFR3 --- HER2 | SID124350107 | Drug Info |
| EGFR3 --- HER2 | N-[1-(3-Fluoro-benzyl)-1H-indazol-5-yl]-5-[morpholin-4-yliminomethyl]-pyrimidine-4,6-diamine | Drug Info |
| EGFR3 --- HER2 | N-[4-(4-Benzyloxy-phenylamino)-quinazolin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | 4-Diisopropylamino-but-2-ynoic acid [4-(3-bromo-phenylamino)-3-cyano-quinolin-6-yl]-amide | Drug Info |
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