| References |
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| REF 1 |
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src. Mol Cell. 1999 Dec;4(6):1041-9.
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| REF 2 |
TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction. J Biol Chem. 1999 Oct 15;274(42):30202-8.
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Role of growth arrest and DNA damage-inducible in Akt phosphorylation and ubiquitination after mechanical stress-induced vascular injury. Am J Respir Crit Care Med. 2011 Nov 1;184(9):1030-40.
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| REF 4 |
RanBPM interacts with TRI, TRAF6 and curbs TGF induced nuclear accumulation of TRI. Cell Signal. 2014 Jan;26(1):162-72.
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HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. PLoS One. 2010 Jun 30;5(6):e11380.
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Association between Presenilin-1 and TRAF6 modulates regulated intramembrane proteolysis of the p75NTR neurotrophin receptor. J Neurochem. 2009 Jan;108(1):216-30.
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K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5. Nat Immunol. 2014 Mar;15(3):231-8.
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Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks. Mol Cell Proteomics. 2012 Jul;11(7):M111.016162.
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TRAF6 upregulates expression of HIF-1 and promotes tumor angiogenesis. Cancer Res. 2013 Aug 1;73(15):4950-9.
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| REF 10 |
The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. Nat Immunol. 2010 Sep;11(9):836-45.
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| REF 11 |
Caspase-8 regulation by direct interaction with TRAF6 in T cell receptor-induced NF-kappaB activation. Curr Biol. 2006 Aug 22;16(16):1666-71.
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| REF 12 |
Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne. Nat Struct Mol Biol. 2010 Aug;17(8):939-47.
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| REF 13 |
IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B. J Biol Chem. 2001 Nov 9;276(45):41661-7.
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| REF 14 |
FOSL1 Inhibits Type I Interferon Responses to Malaria and Viral Infections by Blocking TBK1 and TRAF3/TRIF Interactions. MBio. 2017 Jan 3;8(1). pii: e02161-16.
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A20-binding inhibitor of NF-B (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein activation and protects from inflammatory disease. Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):E998-1006.
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| REF 16 |
Interaction of Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and Vav3 in the Receptor Activator of Nuclear Factor B (RANK) Signaling Complex Enhances Osteoclastogenesis. J Biol Chem. 2016 Sep 23;291(39):20643-60.
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| REF 17 |
Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3533-8.
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| REF 18 |
Cytokine-induced activation of mixed lineage kinase 3 requires TRAF2 and TRAF6. Cell Signal. 2009 Nov;21(11):1620-5.
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| REF 19 |
PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation. J Biol Chem. 2010 Jan 15;285(3):2077-89.
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Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway. Mol Cell Biol. 2001 Apr;21(7):2475-84.
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| REF 21 |
The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway. EMBO J. 2000 Apr 3;19(7):1576-86.
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| REF 22 |
ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction. J Biol Chem. 2000 Oct 20;275(42):32747-52.
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| REF 23 |
Direct activation of protein kinases by unanchored polyubiquitin chains. Nature. 2009 Sep 3;461(7260):114-9.
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| REF 24 |
USP2a positively regulates TCR-induced NF-B activation by bridging MALT1-TRAF6. Protein Cell. 2013 Jan;4(1):62-70.
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Expression of the nuclear factor-B inhibitor A20 is altered in the cystic fibrosis epithelium. Eur Respir J. 2013 Jun;41(6):1315-23.
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| REF 26 |
Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6. Mol Cell Biol. 2002 Feb;22(4):992-1000.
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