| References |
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Identification of proteins associated with ligand-activated estrogen receptor in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS. Proteomics. 2011 Jan;11(1):172-9.
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| REF 2 |
Regulation of the HIF-1alpha stability by histone deacetylases. Oncol Rep. 2007 Mar;17(3):647-51.
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| REF 3 |
HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene. 2005 Apr 28;24(19):3110-20.
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| REF 4 |
Chrysin inhibits expression of hypoxia-inducible factor-1alpha through reducing hypoxia-inducible factor-1alpha stability and inhibiting its protein synthesis. Mol Cancer Ther. 2007 Jan;6(1):220-6.
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| REF 5 |
Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha. FEBS J. 2009 Jul;276(13):3470-80.
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A cross-talk between hypoxia and TGF-beta orchestrates erythropoietin gene regulation through SP1 and Smads. J Mol Biol. 2004 Feb 6;336(1):9-24.
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| REF 7 |
FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev. 2001 Oct 15;15(20):2675-86.
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| REF 8 |
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1 to promote cell-cycle progression. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3325-34.
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| REF 9 |
Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha. Cancer Res. 2006 Sep 1;66(17):8814-21.
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| REF 10 |
Inhibition of SIRT1 impairs the accumulation and transcriptional activity of HIF-1 protein under hypoxic conditions. PLoS One. 2012;7(3):e33433.
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| REF 11 |
NQO1 inhibits proteasome-mediated degradation of HIF-1. Nat Commun. 2016 Dec 14;7:13593.
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| REF 12 |
Hypoxia induced E-cadherin involving regulators of Hippo pathway due to HIF-1 stabilization/nuclear translocation in bone metastasis from breast carcinoma. Exp Cell Res. 2015 Jan 15;330(2):287-99.
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| REF 13 |
Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function. J Biol Chem. 2003 Apr 18;278(16):13595-8.
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| REF 14 |
CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016 Jan 1;129(1):191-205.
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| REF 15 |
The zinc chelator, N,N,N',N'-tetrakis (2-pyridylmethyl) ethylenediamine, increases the level of nonfunctional HIF-1alpha protein in normoxic cells. Biochem Biophys Res Commun. 2006 May 19;343(4):1002-8.
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| REF 16 |
COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70. PLoS One. 2009 Oct 5;4(10):e7332.
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| REF 17 |
The TIP60 Complex Is a Conserved Coactivator of HIF1A. Cell Rep. 2016 Jun 28;16(1):37-47.
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| REF 18 |
Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways. J Biol Chem. 2002 Nov 15;277(46):43799-808.
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| REF 19 |
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 1999 May 20;399(6733):271-5.
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| REF 20 |
SIRT2 regulates tumour hypoxia response by promoting HIF-1 hydroxylation. Oncogene. 2015 Mar 12;34(11):1354-62.
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Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha. Mol Cell. 2010 Jun 25;38(6):864-78.
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| REF 22 |
HIF-1alpha induces cell cycle arrest by functionally counteracting Myc. EMBO J. 2004 May 5;23(9):1949-56.
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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. Science. 2002 Feb 1;295(5556):858-61.
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| REF 24 |
HIF1-Induced by Lysophosphatidic Acid Is Stabilized via Interaction with MIF and CSN5. PLoS One. 2015 Sep 9;10(9):e0137513.
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TRAF6 upregulates expression of HIF-1 and promotes tumor angiogenesis. Cancer Res. 2013 Aug 1;73(15):4950-9.
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A unique SUMO-2-interacting motif within LANA is essential for KSHV latency. PLoS Pathog. 2013;9(11):e1003750.
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MCM proteins are negative regulators of hypoxia-inducible factor 1. Mol Cell. 2011 Jun 10;42(5):700-12.
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Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1. EMBO J. 2006 Mar 22;25(6):1231-41.
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| REF 29 |
The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1alpha (HIF-1alpha ) and inhibits HIF-1-mediated transcription. J Biol Chem. 2001 Jul 27;276(30):28421-9.
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